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(Apo Lorazepam)
4,341 results
  • Pharmacological and neurosurgical interventions for managing dystonia in cerebral palsy: a systematic review. [Journal Article]
  • DMDev Med Child Neurol 2018 Feb 06
  • Fehlings D, Brown L, … Walters I
  • CONCLUSIONS: For dystonia reduction, ITB and DBS are possibly effective, whereas trihexyphenidyl was possibly ineffective. There is insufficient evidence to support oral medications or botulinum toxin to reduce dystonia. There is insufficient evidence for pharmacological and neurosurgical interventions to improve motor function, decrease pain, and ease caregiving. The majority of the pharmacological and neurosurgical management of dystonia in CP is based on clinical expert opinion.Intrathecal baclofen and deep brain stimulation are possibly effective in reducing dystonia. Current evidence does not support effectiveness of oral medications or botulinum toxin to reduce dystonia. Evidence is inadequate for pharmacological/neurosurgical interventions impact on improving motor function, pain/comfort, and easing caregiving. The majority of the care pathway rests on expert opinion.
  • Systematic review of catatonia treatment. [Review]
  • NDNeuropsychiatr Dis Treat 2018; 14:317-326
  • Pelzer AC, van der Heijden FM, den Boer E
  • CONCLUSIONS: Lorazepam and ECT are effective treatments for which clinical evidence is found in the literature. It is not possible to develop a treatment protocol because the evidence for catatonia management on the basis of the articles reviewed is limited. Stringent treatment studies on catatonia are warranted.
  • The curse of relieving pain. [Journal Article]
  • BCBMJ Case Rep 2018 Jan 24; 2018
  • Said A, Halalau A
  • A 39-year-old woman with a history of chronic back pain due to spinal haemangiomas, multiple malignancies and depression was brought by Emergency medical servicesS to the emergency centre (EC) after ...
  • Sedative Plasma Concentrations and Delirium Risk in Critical Illness. [Journal Article]
  • APAnn Pharmacother 2018 Jan 01; :1060028017753480
  • Stollings JL, Thompson JL, … Patel MB
  • CONCLUSIONS: In critically ill patients, higher lorazepam plasma concentrations were associated with delirium, whereas dexmedetomidine plasma concentrations were not. This implies that the reduced delirium risk seen in patients sedated with dexmedetomidine may be a result of avoidance of benzodiazepines, rather than a dose-dependent protective effect of dexmedetomidine.
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