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(Apo Sulin)
2,001 results
  • Microsatellite Instability in Mouse Models of Colorectal Cancer. [Journal Article]
  • CJCan J Gastroenterol Hepatol 2018; 2018:6152928
  • Currey N, Daniel JJ, … Kohonen-Corish MRJ
  • Microsatellite instability (MSI) is caused by DNA mismatch repair deficiency and is an important prognostic and predictive biomarker in colorectal cancer but relatively few studies have exploited mou...
  • Oxazole and thiazole analogs of sulindac for cancer prevention. [Journal Article]
  • FMFuture Med Chem 2018 Apr 01; 10(7):743-753
  • Mathew B, Hobrath JV, … Reynolds RC
  • CONCLUSIONS: In general, replacement of the amide function of SSA analogs had a negative impact on the cell lines tested. A small number of hits incorporating rigid oxazole or thiazole groups in the sulindac scaffold in place of the amide linkage show comparable activity to our lead agent SSA.
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