- Many diagnostic tools for appendicitis: a scoping review. [Review]Surg Endosc. 2023 Feb 03 [Online ahead of print]SE
- CONCLUSIONS: We identified 82 diagnostic tools that most frequently were based on symptoms and physical examinations. Most diagnostic tools relied on a medical doctor/surgeon with access to laboratory values. The accuracy was high across the diagnostic tools.
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- Patrinoside and Patrinoside A from Patrinia scabiosaefolia Improve Insulin Resistance by Inhibiting NF-κB, MAPK Pathways and Oxidative Stress in RAW264.7 and 3 T3-L1 Cells. [Journal Article]Oxid Med Cell Longev. 2023; 2023:9069645.OM
- Patrinia scabiosaefolia, as traditional food and medicine plant, was used to treat appendicitis, enteritis, and hepatitis for thousand years in China. Patrinoside and patrinoside A isolated from P. scabiosaefolia could significantly improve insulin resistance (IR) by activating PI-3 K/AKT signaling pathway in our previous study. Since IR is closely related to inflammation, their anti-inflammatory…
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- [Small Bowel Obstruction Due to Internal Hernia Caused by the Vermiform Appendix, Mesentery of the Small Intestines, and Greater Omentum in a Patient with No History of Abdominal Surgery]. [Journal Article]Gan To Kagaku Ryoho. 2022 Dec; 49(13):1556-1558.GT
- Our patient was a 69-year-old man being treated for hyperlipidemia. He was admitted to our hospital with the chief complaint of vomiting and abdominal pain. Abdominal computed tomography(CT)showed dilation of the distal small intestines, a small amount of ascites in the small intestines near the right pelvis, and a closed loop of the small intestine. Enhanced abdominal CT was performed to evaluat…
- [A Case of Low-Grade Appendiceal Mucinous Neoplasm with Extra-Appendiceal Mucin Extrusion Successfully Treated with Laparoscopic Surgery]. [Journal Article]Gan To Kagaku Ryoho. 2022 Dec; 49(13):1458-1460.GT
- A 49-year-old male patient, who presented with abdominal pain, was suspected of having acute appendicitis. Abdominal computed tomography revealed a swollen appendix, accompanied by a 40 mm low-density mass located behind the appendix. He was diagnosed with an appendiceal mucinous neoplasm, and laparoscopic ileocecal resection was performed. A soft tumor was found proximal to the swollen appendix …
- Failure to Rescue and Mortality Differences After Appendectomy in a Low-Middle-Income Country and the United States. [Journal Article]Anesth Analg. 2022 Dec 26 [Online ahead of print]A&A
- CONCLUSIONS: Despite lower rates of postoperative complications, in-hospital mortality after appendectomy was higher in Colombia than in the United States. This difference may be explained by higher rates of failure to rescue in the low-to-middle-income country (ie, decreased ability of Colombian hospitals to rescue patients from complications).
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- Impact of visceral obesity on the short-term outcomes after laparoscopic appendectomy. [Journal Article]Scand J Gastroenterol. 2023 Feb 02 [Online ahead of print]SJ
- CONCLUSIONS: Visceral obesity is one of the independent risk factors for incisional infection after LA, and can be used as one of the reference indicators for prognostic assessment of short-term outcomes after LA.
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- Smoking, Alcohol consumption, and 24 Gastrointestinal Diseases: Mendelian Randomization Analysis. [Journal Article]Elife. 2023 Feb 02; 12E
- Background: Whether the positive associations of smoking and alcohol consumption with gastrointestinal diseases are causal is uncertain. We conducted this Mendelian randomization (MR) to comprehensively examine associations of smoking and alcohol consumption with common gastrointestinal diseases.
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- Appendicitis Inflammatory Response Score in Acute Appendicitis: A Study at a Tertiary Care Center in North India. [Journal Article]
- CONCLUSIONS: AIR score has a high sensitivity and positive predictive value in the diagnosis of acute appendicitis. It is a quick and convenient system for clinical evaluation of patients in primary care or peripheral hospitals where advanced facilities such as USG scan or CT scan are not available all the time. The application of this scoring system definitely improves diagnostic accuracy and reduces negative appendectomy rate.
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- Maternal Smoking During Pregnancy and Risk of Appendicitis in the Offspring. [Journal Article]Epidemiology. 2023 Mar 01; 34(2):293-301.E
- CONCLUSIONS: Maternal smoking during pregnancy and appendicitis in the offspring may be associated.
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- Prospective study of laparoscopic management of appendicitis during the COVID pandemic in a single paediatric centre. [Journal Article]Afr J Paediatr Surg. 2023 Jan-Mar; 20(1):40-45.AJ
- CONCLUSIONS: Despite a delayed presentation to hospital, there was no rise in the incidence of complicated appendicitis, complications of surgery or length of stay during the COVID-19 pandemic. Laparoscopic appendicectomy was also shown to be a safe and effective standard for the management of appendicitis during the pandemic.
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- Are only a few hours adequate for hospitalisation following mini-incision open appendectomy in paediatric patients? [Journal Article]Afr J Paediatr Surg. 2023 Jan-Mar; 20(1):28-33.AJ
- CONCLUSIONS: The idea of immediate discharge within 3 h seems to be feasible for children with acute simple appendicitis who were treated with open appendectomy. We believe that the practice will be widely acknowledged and proceed to reduce the resources and the expenses in the hospital.
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- Clinical practice selectively follows acute appendicitis guidelines. [Journal Article]
- CONCLUSIONS: The observed diagnostic and treatment practices of the participating institutions displayed variability in compliance with key recommendations from existing guidelines. In general, practice was congruent with recommendations for preoperative antibiotic surgical site infection prophylaxis administration, time to surgery, and operative approach. However, there remains opportunities for improvement in the choice of diagnostic imaging modality, postoperative antibiotic stewardship to timely discontinue prophylactic antibiotics, and the implementation of ambulatory treatment pathways for uncomplicated appendicitis in the healthy young adult.
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- Acute Appendicitis in Infants - A Report of Two Cases. [Case Reports]
- Acute appendicitis is the most common surgical emergency in children. However, it is uncommon in neonates and infants. Often it can be challenging to diagnose acute appendicitis in children due to atypical clinical presentation and nonspecific symptoms. This is particularly true in neonates and infants. A high level of clinical suspicion is needed to diagnose infantile appendicitis. Delayed diagn…
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- Subhepatic Appendicitis Presenting With Recurrent Abdominal Pain. [Case Reports]
- Gut malrotation may result in failure of descent of the cecum to the right iliac fossa, resulting in the anomaly where the cecum and appendix are situated in the subhepatic/gallbladder region. Although the true incidence of subhepatic cecum or appendix is not known, there is a handful of case reports in the literature describing the diagnosis and management of subhepatic appendicitis and associat…
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- Large Mucocele of the Appendix Discovered in a 48-Year-Old Male Presenting With Appendicitis: A Case Report. [Case Reports]
- The appendix is a vermiform-like organ that extends from the cecum and has been thought of as having a rudimentary immunologic function. However, the appendix can become distended and mucus-filled, classifying it as a mucocele appendix. Mucoceles can be found in various locations in the body, including the colon and the appendix, and have malignancy potential. We report a case of a 48-year-old ma…
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- Comparison of Alvarado score, appendicitis inflammatory response score (AIR) and Raja Isteri Pengiran Anak Saleha appendicitis (RIPASA) score in predicting acute appendicitis. [Journal Article]
- CONCLUSIONS: RIPASA score is an overall better scoring system in diagnosing acute appendicitis in compared to Alvarado and AIR score.
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- The incidence of new mental health disorders after acute pancreatitis: A large, propensity-matched, observational study. [Journal Article]Pancreatology. 2023 Jan 18 [Online ahead of print]P
- CONCLUSIONS: Compared with controls, patients with AP had significantly higher rates of new MHDs and their associated pharmacotherapies at one-year, suggesting that a single episode of AP may independently place patients at risk for developing MHDs irrespective of whether they go on to develop CP.
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- Risk factors for postoperative morbidity, prolonged length of stay and hospital readmission after appendectomy for acute appendicitis. [Journal Article]Eur J Trauma Emerg Surg. 2023 Jan 28 [Online ahead of print]EJ
- CONCLUSIONS: Among patients undergoing appendectomy for acute appendicitis, there are relevant risk factors predicting postoperative complications, prolonged hospital stays and readmission. Patients with the presence of the identified risk factors should receive special attention in the postoperative course and may benefit from a more individualized therapy.
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- Is it possible to predict the severity of acute appendicitis? Reliability of predictive models based on easily available blood variables. [Journal Article]
- CONCLUSIONS: Low lymphocyte count and high CRP/Albumin ratio combined into a predictive model may have a role in the selection of patients who deserve appendicectomy instead of non-operative management of acute appendicitis.
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- Role of Conservative Management in Stump Appendicitis: A Case Series. [Journal Article]
- Stump appendicitis is a rare, delayed complication of appendectomy. It is seen following both open and laparoscopic appendectomy and may occur weeks to years following the initial appendectomy. We report two cases of stump appendicitis seen at our hospital. Both cases were diagnosed based on radiological findings and successfully managed conservatively with antibiotics. Although the usually recom…
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- Omental torsion; an unusual case of acute abdomen. Case report. [Case Reports]
- CONCLUSIONS: It is important to consider omental torsion as another differential diagnosis of acute abdomen, which can be satisfactorily resolved via laparoscopy, thus avoiding the development of complications associated with its natural evolution.
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- A case of mesenteric venous thrombosis complicating appendiceal diverticulitis. [Journal Article]
- CONCLUSIONS: We report a successfully treated case of MVT complicating appendiceal diverticulitis by surgical intervention. This is the first case of MVT complicating appendiceal diverticulitis.
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- Alvarado or RIPASA? Which one do you use to diagnose acute appendicitis?: A cross-sectional study. [Journal Article]Health Sci Rep. 2023 Jan; 6(1):e1078.HS
- CONCLUSIONS: The RIPASA score system had higher sensitivity, PPV, NPV, and accuracy than the Alvarado one. It is recommended for the physician and surgeon to evaluate patients with RIF pain using the RIPASA score.
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- Value Added from Same-day Discharge after Appendectomy for Children with Simple Appendicitis. [Journal Article]Pediatr Qual Saf. 2023 Jan-Feb; 8(1):e629.PQ
- CONCLUSIONS: Using quality improvement methodology and care standardization, we significantly improved the rate of same-day discharge after appendectomy for simple appendicitis without impacting emergency department visits or readmissions. As a result, our health care system saved 140 hospital days over the first 21 months.
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- The impact of the COVID-19 outbreak on emergency general surgery in the first German "hotspot region" Aachen-Heinsberg-A multicentre retrospective cohort study. [Journal Article]PLoS One. 2023; 18(1):e0280867.Plos
- This study aimed to observe the impact of the COVID-19 outbreak on acute general surgery in the first German "hotspot" regions of Heinsberg and Aachen, during the first months of the pandemic. The incidence and severity of acute appendicitis, acute cholecystitis and mechanical bowel obstruction, were compared between March and May 2020 and a control period (same months of the previous three years…
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- Does the timing of appendectomy affect outcomes and postoperative complications? [Journal Article]Pediatr Surg Int. 2023 Jan 25; 39(1):90.PS
- CONCLUSIONS: These results show that in our institution time slot in which the appendectomy is performed has no consequences in postoperative outcomes and complications.
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- Techniques for mesoappendix transection and appendix resection: insights from the ESTES SnapAppy study. [Journal Article]Eur J Trauma Emerg Surg. 2023 Jan 24 [Online ahead of print]EJ
- CONCLUSIONS: Safe mesoappendix transection and appendix resection are accomplished using heterogeneous techniques. Technique selection for both mesoappendix transection and appendix resection correlates with AAST grade. Higher grade led to more ultrasonic tissue transection and stapled appendix resection. Higher AAST appendicitis grade also correlated with infection-related complication occurrence. Despite the overall well-tolerated heterogeneity of approaches to acute appendicitis, increasing disease acuity or complexity appears to encourage homogeneity of intraoperative surgical technique toward advanced adjuncts.
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- Acute appendicitis manifests as two microbiome state types with oral pathogens influencing severity. [Journal Article]
- Mounting evidence suggests that acute appendicitis (AA) is not one but two diseases: complicated appendicitis, which is associated with necrosis leading to perforation or periappendicular abscess, and uncomplicated appendicitis, which does not necessarily result in perforation. Even though AA is the most frequent cause of surgery from abdominal pain, little is known about the origins and etiopath…
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- Application value of high-frequency ultrasonography in endoscopic retrograde appendicitis therapy for pediatric acute appendicitis. [Journal Article]Surg Endosc. 2023 Jan 23 [Online ahead of print]SE
- CONCLUSIONS: Endoscopic intra-appendiceal irrigation under the guidance of high-frequency ultrasonography is a real-time and convenient method that is safe and effective in treating pediatric acute appendicitis.
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- Clinical analysis of 48 cases of acute complex appendicitis treated by appendectomy with double purse-bag method. [Letter]Asian J Surg. 2023 Jan 21 [Online ahead of print]AJ
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