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Unbound Medicine.
(Arctium lappa)
421 results
  • The complete mitochondrial genome of Aucklandia lappa Decne. (Asteraceae, Aucklandia Falc.). [Journal Article]
    Mitochondrial DNA B Resour. 2021 May 19; 6(6):1691-1693.Song YY, Zhang TT, … Kang TG
  • The complete mitochondrial genome of Aucklandia lappa was sequenced for the first time. The mitochondrial genome length was 320,439 bp, with 45.05% GC contents. There were 67 genes annotated, including 31 known protein-coding genes, 25 tRNAs, and six rRNAs. The maximum likelihood method was used to establish the phylogenetic tree of 37 species. Results have shown that A. lappa and Arctium lappa w…
  • Discover Quality Control Ingredients in Burdock root by Combining Anti-tumor Effects and UHPLC-QqQ-MS/MS. [Journal Article]
    Biomed Chromatogr. 2021 Jun 01 [Online ahead of print]Zhang M, Wang YW, … Gu XL
  • Burdock root is the root of Arctium lappa L., a plant of the compositae family, which has the effects of dispersing wind and heat, detoxifying, and reducing swelling. In order to better control the quality of burdock root, a screening study of quality control indicators was carried out. The current research combines biological activity evaluation with chemical analysis to screen and identify the …
  • Derma-Hc, a New Developed Herbal Formula, Ameliorates Cutaneous Lichenification in Atopic Dermatitis. [Journal Article]
    Int J Mol Sci. 2021 Feb 26; 22(5)Nam YK, Kim MH, … Yang WM
  • Atopic dermatitis (AD) is a chronic cutaneous disorder that is characterized by severe eczematous inflammation, swelling, and lichenification. Activation of T helper (Th)-22 cells by allergens leads to epidermal hyperplasia with hyperkeratosis at the chronic phase of AD. Derma-Hc is composed of five natural herbs with anti-AD effects, such as Astragalus membranaceus BUNGE, Schizonepeta tenuifolia…
  • Arctigenin Triggers Apoptosis and Autophagy via PI3K/Akt/mTOR Inhibition in PC-3M Cells. [Journal Article]
    Chem Pharm Bull (Tokyo). 2021 May 01; 69(5):472-480.Sun BL, Cai EB, … Wang JY
  • Arctigenin (ARG), a natural lignans compound isolated from Arctium lappa L. In this study, the anti-tumor effect of ARG on prostate cancer cell PC-3M and the mechanism of apoptosis and autophagy induced by phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling pathway were discussed, and further confirmed by the joint treatment of ARG and PI3K inhibitor LY294002. …
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