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(Arimidex)
2,058 results
  • Aromatase inhibitors (letrozole) for subfertile women with polycystic ovary syndrome. [Review]
  • CDCochrane Database Syst Rev 2018 05 24; 5:CD010287
  • Franik S, Eltrop SM, … Farquhar C
  • CONCLUSIONS: Letrozole appears to improve live birth and pregnancy rates in subfertile women with anovulatory polycystic ovary syndrome, compared to clomiphene citrate. There is high-quality evidence that OHSS rates are similar with letrozole or clomiphene citrate. There is high-quality evidence of no difference in miscarriage rates or multiple pregnancy rates. There is low-quality evidence of no difference in live birth and pregnancy rates between letrozole and laparoscopic ovarian drilling, although there were few relevant studies. For the 2018 update, we added good-quality trials, upgrading the quality of the evidence.
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