- The efficacy of intra-articular triamcinolone acetonide 10 mg vs. 40 mg in patients with knee osteoarthritis: a non-inferiority, randomized, controlled, double-blind, multicenter study. [Journal Article]BMC Musculoskelet Disord. 2023 Feb 03; 24(1):92.BM
- CONCLUSIONS: The 10 mg of TA is non-inferior to 40 mg TA in improving pain in patients with symptomatic knee OA. Both 10 mg and 40 mg of TA significantly improved pain and quality of life in patients with symptomatic knee OA.
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- A Rare Symptom of Secondary Infection After Facial Thread Lift and Its Treatment. [Journal Article]J Craniofac Surg. 2023 Feb 03 [Online ahead of print]JC
- Facial esthetics is concerned with the harmonious beauty of the face. The skin, soft tissues, and bone tissues of the face degenerate as people age. Facial thread lift is a new minimally invasive esthetic technique that uses threads embedded within different tissue layers to reposition and support lax tissues. The authors report a 35-year-old female patient who developed an infection after underg…
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- Surgical demonstration of pressure differential through an optic disc pit. [Journal Article]Retin Cases Brief Rep. 2022 Nov 16 [Online ahead of print]RC
- CONCLUSIONS: Communication between the vitreous cavity and the perineural space of the optic nerve is described histologically. Our case demonstrated dynamic flow through the optic disc pit with intraoperative fluctuation of intraocular pressure.
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- Extracorporeal shock wave therapy versus corticosteroid local injection in shoulder impingement syndrome: a three-arm randomized controlled trial. [Journal Article]Am J Phys Med Rehabil. 2022 Nov 30 [Online ahead of print]AJ
- CONCLUSIONS: The addition of ESWT to CPT induced more noticeable intermediate-term effects than CPT plus LCI or CPT alone.
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- Comparison of statins with steroids and botulinum toxin A in the prevention of benign strictures after esophageal endoscopic submucosal dissection: a retrospective cohort study. [Journal Article]Surg Endosc. 2023 Feb 02 [Online ahead of print]SE
- CONCLUSIONS: Statins may be a potential treatment to prevent esophageal strictures after extensive ESD; however, clinical trials should be conducted to validate this.
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- Refractory Keratolimbal Allograft Rejection in Autoimmune Polyglandular Syndrome-Associated Keratopathy Treated With Intravenous Immunoglobulin. [Journal Article]Cornea. 2023 Jan 11 [Online ahead of print]C
- CONCLUSIONS: Treatment with prolonged IVIG showed better improvement in a case of acute rejection refractory to traditional treatments, especially in the setting of HLA antibodies. The case demonstrates that close follow-up with a corneal specialist and collaboration with a transplant specialist is important to monitor for postoperative KLAL rejection.
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- Injection Therapy for Digital Mucous Cysts. [Letter]J Cutan Med Surg. 2023 Jan 31 [Online ahead of print]JC
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- Intralesional injection of platelet-rich plasma versus steroid in the treatment of oral lichen planus. [Journal Article]J Cosmet Dermatol. 2023 Jan 31 [Online ahead of print]JC
- CONCLUSIONS: Intralesional PRP is a good and safe modality for treatment of OLP and intralesional TA. However, there were some side effects and recurrence of disease after follow-up for three months in patients treated by PRP more than those treated by TA.
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- Granulomatosis with polyangiitis-associated sclerokeratitis in a case of ocular adnexal B-cell lymphoma. [Journal Article]Orbit. 2023 Jan 30 [Online ahead of print]O
- We describe the first reported case of granulomatosis polyangiitis (GPA)-associated sclerokeratitis in a patient with treated ocular adnexal lymphoma (OAL). The patient presented with pain and decreased vision in the left eye over several weeks. Past medical history was significant for recent bilateral relapsing OAL that was treated successfully with radiotherapy. Examination of the eyes revealed…
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- Suprachoroidal injection of triamcinolone acetonide plus intravitreal bevacizumab in diabetic macular edema: a randomized pilot trial. [Randomized Controlled Trial]
- CONCLUSIONS: Significant improvements in BCVA and retinal anatomical outcomes demonstrated the additive effects of SCTA to those of anti-vascular endothelial growth factors with no short-term side effects and this combination appears to be a promising option in the management of patients with CI-DME.
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- Pars Plana Vitrectomy With Internal Limiting Membrane Peeling for the Treatment of Cystoid Macular Edema in a Patient With Syphilitic Uveitis and HIV Infection. [Case Reports]Cureus. 2022 Dec; 14(12):e32865.C
- We report a case of cystoid macular edema (CME) secondary to syphilitic uveitis that was successfully treated with pars plana vitrectomy with internal limiting membrane peeling. A 37-year-old male with a history of HIV developed a CME secondary to syphilitic panuveitis. His uveitis resolved following treatment with intravenous penicillin, yet his CME persisted and was refractory to four posterior…
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- Common Dermatologic Conditions in Skin of Color. [Journal Article]Am Fam Physician. 2023 Jan; 107(1):26-34.AF
- Individuals with skin of color represent a diverse population of racial and ethnic backgrounds, including but not limited to Black or African American, American Indian or Alaska Native, Asian American or Pacific Islander, Hispanic or Latino, and Middle Eastern or North African. Dermatologic health disparities exist in part because of systemic racism and are exacerbated by inadequate physician tra…
- Fabrication and Characterisation of 3D-Printed Triamcinolone Acetonide-Loaded Polycaprolactone-Based Ocular Implants. [Journal Article]
- Triamcinolone acetonide (TA) is a corticosteroid that has been used to treat posterior segment eye diseases. TA is injected intravitreally in the management of neovascular disorders; however, frequent intravitreal injections result in many potential side effects and poor patient compliance. In this work, a 3D bioprinter was used to prepare polycaprolactone (PCL) implants loaded with TA. Implants …
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- Photodynamic Therapy, Photobiomodulation and Acetonide Triamcinolone 0.1% in the Treatment of Oral Lichen Planus: A Randomized Clinical Trial. [Journal Article]
- CONCLUSIONS: Photodynamic therapy and photobiomodulation once a week for four weeks are safe and non-invasive treatment options, with the important advantage of lacking adverse effects. Further studies are needed to confirm it.
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- Intra-Articular Injection of Botulinum Toxin for the Treatment of Knee Osteoarthritis: A Systematic Review of Randomized Controlled Trials. [Review]
- The purpose of the present paper was to review the available evidence on intra-articular botulinum toxin (BTX) injection in the treatment of knee osteoarthritis and to compare it to other conservative treatment options. A systematic review of the literature was performed on the PubMed, Scopus, Cochrane Library, Web of Science, Pedro and Research Gate databases with the following inclusion criteri…
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- The Effectiveness of Facet Joint Injection with Steroid and Botulinum Toxin in Severe Lumbar Central Spinal Stenosis: A Randomized Controlled Trial. [Randomized Controlled Trial]
- Lumbar central spinal stenosis (LCSS) is a common disorder that causes disability and pain in the elderly. It causes pain in the radicular leg. Recently, transforaminal epidural steroid injection (TFESI) has been widely used to control radicular leg pain caused by LCSS. However, in cases of severe LCSS, drugs injected using TFESI cannot spread into the spinal canal and would have less therapeutic…
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- Intralesional corticosteroid administration in the treatment of keloids: a scoping review on injection methods. [Review]Dermatology. 2023 Jan 19 [Online ahead of print]D
- Background Intralesional corticosteroid administration (ICA) is a first-line treatment for keloids. However, its clinical results are still highly variable and often suboptimal. Treatment results may strongly be influenced by various operator dependent factors. The aim of this study is to map the details of ICA in keloids described in randomized controlled trials (RCTs), hence presenting the scie…
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- The effect of bevacizumab, 5-fluorouracil, and triamcinolone on the healing modulation of surgical wounds in rats. [Journal Article]Histol Histopathol. 2023 Jan 11 [Online ahead of print]HH
- In this study, we aimed to analyze the effect of 5-fluorouracil, triamcinolone, and bevacizumab on scar modulation in an experimental rat model of surgical lesions. Rats (Rattus norvegicus albinus) were divided into four groups: bevacizumab, 5-fluorouracil + triamcinolone, bevacizumab + 5-fluorouracil + triamcinolone, and control (received no medication) groups. A linear, dorsal incision was crea…
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- Drugs and Lactation Database (LactMed): Triamcinolone [BOOK]Drugs and Lactation Database (LactMed). National Library of Medicine (US): Bethesda (MD)BOOK
- Because no information is available on the use of oral or injectable triamcinolone during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. However, use of triamcinolone as a nasal spray or local injections, such as for tendinitis, would not be expected to cause any adverse effects in breastfed infants. Expert opinion considers inhaled and or…
- Transfer of Injected Triamcinolone into Human Milk of a Lactating Patient Suffering from Idiopathic Granulomatous Mastitis. [Case Reports]Breastfeed Med. 2023 Jan; 18(1):74-77.BM
- Background: Idiopathic granulomatous mastitis (IGM) is a chronic inflammatory condition of the mammary gland that presents as a painful mass, and it must be distinguished from both infectious mastitis and breast cancer. When diagnosed during lactation, it can result in significant distress and early weaning. Injection of triamcinolone has been used as a successful treatment method, but safety in …
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- Retinal arterial occlusive vasculitis after multiple intravitreal brolucizumab injections for diabetic macular edema. [Case Reports]
- CONCLUSIONS: Diagnosis and treatment at a relatively early stage after the onset of IOI prevented severe visual impairment in this case. Topical betamethasone eye drops reduced anterior chamber inflammation associated with IVBr; however, vascular sheathing worsened when topical drops alone was used. Occlusive retinal vasculitis, diagnosed with fluorescein angiography (FA) and OCTA, appeared to stabilize when subtenon triamcinolone injection was added to topical steroid administration. Because the central macula was not involved, severe vision loss was prevented. It is unknown if topical steroid administration would be adequate to prevent worsening of occlusive vasculitis in other cases. Although not used in this case, oral prednisone is one treatment option that may prevent severe vision loss. However, it requires monitoring of side effects, such as elevated blood glucose levels. PRP is also an option in cases where progression of proliferative changes is a concern, as was done in this case. With these considerations in mind, it is important to diagnose brolucizumab-associated IOI and subsequent retinal arterial occlusive vasculitis in DME patients early and initiate treatment to prevent severe visual impairment. Diagnosing new IOI and subsequent retinal arterial occlusive vasculitis is more difficult in DME than in neovascular age-related macular degeneration because of the inflammatory component often associated vascular occlusions. Therefore, early IOI diagnosis and follow-up using various instruments such as laser flare cell meter, wide-field color imaging, OCT/OCTA, and FA, in addition to usual comprehensive ophthalmologic examinations, is crucial.
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- Erratum: Retraction of Figure 1 in the Article "Immediate Hypersensitivity Reactions Induced by Triamcinolone in a Patient With Atopic Dermatitis". [Published Erratum]
- This corrects the article on p. e87 in vol. 33, PMID: 29542298.
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- Intraocular Pressure Elevation After Posterior Subtenon Triamcinolone Acetonide Injection in Pediatric Non-Infectious Uveitis. [Journal Article]
- CONCLUSIONS: In our study, an IOP elevation rate as high as 47% was found in pediatric non-infectious uveitis patients following only a single PSTA injection. Steroid-induced IOP elevation and resistant glaucoma can develop even after the first PSTA administration in pediatric uveitis. Filtration surgery and the excision of subtenon triamcinolone deposits, when present, are important in glaucoma management. The risk/benefit ratio must be carefully considered when administering steroid injections to children with uveitis.
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- Response of intra canal medicaments on viability and survival of SHEDs. [Journal Article]J Clin Pediatr Dent. 2022 Sep; 46(5):65-71.JC
- CONCLUSIONS: Potassium iodide and glutaraldehyde were the significantly less likely of all the medications examined to adversely affect the viability and survival of SHEDs.
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- EGCG inhibits hypertrophic scar formation in a rabbit ear model. [Journal Article]J Cosmet Dermatol. 2023 Jan 06 [Online ahead of print]JC
- CONCLUSIONS: EGCG may serve as a useful candidate therapeutic drug for hypertrophic scar via inhibiting fibrotic gene expression and suppressing angiogenesis.
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- Retinal Pigment Epithelial Detachment Associated with Immunoglobulin A Nephropathy: A Case Report. [Case Reports]Case Rep Ophthalmol. 2022 Sep-Dec; 13(3):834-841.CR
- Uveitis and scleritis are eye diseases associated with immunoglobulin A (IgA) nephropathy, but reports on retinal pigment epithelial detachment (PED) in relation to IgA nephropathy are scarce. We have experienced a case of PED associated with IgA nephropathy that was improved by pulse steroid treatment. A 68-year-old woman underwent examination for visual loss in the right eye. Her corrected visu…
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- Safety Profile of Lutein- Versus Triamcinolone Acetonide-Based Vitreous Staining. [Journal Article]
- CONCLUSIONS: LB-VD showed a better safety profile compared with all TA-based formulations, even when used in combination with PFD.
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- Comparison of Outcomes of Two Different Corticosteroid Injection Approaches for Primary Frozen Shoulder: A Randomized Controlled Study. [Randomized Controlled Trial]J Rehabil Med. 2023 Jan 03; 55:jrm00361.JR
- CONCLUSIONS: The anterior approach achieves more satisfactory results in pain control and offers better recovery of functional activity than posterior approach in the early period for primary frozen shoulder.
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