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3,301 results
  • Germ Cell Neoplasia in Situ and Preserved Fertility Despite Suppressed Gonadotropins in a Patient With Testotoxicosis. [Case Reports]
  • JCJ Clin Endocrinol Metab 2017 Dec 01; 102(12):4411-4416
  • Juel Mortensen L, Blomberg Jensen M, … Juul A
  • CONCLUSIONS: The case illustrates that absence of gonadotropins but high intratesticular testosterone concentration is sufficient for spermatogenesis and to allow fatherhood. Our study is also the first description, to our knowledge, of GCNIS in a patient with testotoxicosis. We recommend regular clinical examination and ultrasonic evaluation of the testes in these patients due to potential increased risk of malignancy.
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