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3,352 results
  • Virilising ovarian tumors: a single center experience. [Journal Article]
  • ECEndocr Connect 2018 Nov 01
  • Sehemby MAS, Bansal PAK, … Shah N
  • CONCLUSIONS: Virilising ovarian tumors present with severe hyperandrogenism and hyperandrogenemia. Sertoli-Leydig cell tumor is the most common histological subtype. Surgery is the treatment of choice with good outcome.
  • Sertoli-Leydig cell tumors of ovary: A case series. [Journal Article]
  • MMedicine (Baltimore) 2018; 97(42):e12865
  • Xu Q, Zou Y, Zhang XF
  • CONCLUSIONS: The patients of SLCT can present with hormonal magnification and manifest high AFP, CA125, and T levels. SLCT is characterized by a solid or mixed solid-cystic mass on CT/MR scans, and shows marked or moderated heterogeneous and constantly enhancement upon postcontrast study. The clinical characteristics and imaging findings are features and appropriated imaging should be performed whenever an SLCT is suspected.
  • Ovarian tumors secreting androgens: an infrequent cause of hyperandrogenism. [Journal Article]
  • MGMinerva Ginecol 2018 Oct 02
  • Perez Lana MB, Demayo S, … Nolting M
  • CONCLUSIONS: Sex cord stromal tumors of the ovary are rare, and can be characterized by virilization for most patients. The majority of the tumors are benign, with few cases having low-grade malignancy. The suspicion and correct evaluation of these women will lead to an early diagnosis and improve their quality of life.
  • Results from a Monocentric Long-Term Analysis of 23 Patients with Ovarian Sertoli-Leydig Cell Tumors. [Journal Article]
  • OOncologist 2018 Sep 10
  • Gouy S, Arfi A, … Morice P
  • CONCLUSIONS: Conservative surgery was safe for patients with stage Ia ovarian SLCTs. The place of conservative surgery for stage Ic1 remains to be defined. The best chemotherapy regimen remains to be defined.For stage Ia disease, conservative surgery (in women of reproductive age) was safe and effective for treating ovarian Seroli-Leydig cell tumors. Adjuvant chemotherapy should be proposed for stage Ia when poor prognostic factors are present (poor differentiation, retiform pattern, or heterologous elements). For stage Ic1 and more severe stages, radical surgery and adjuvant chemotherapy should be considered. The combination of bleomycin, etoposide, and cisplatin was the most frequently used regimen, but the best chemotherapy regimen remains to be defined.
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