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(Arrhenoblastoma)
3,318 results
  • DICER1 hotspot mutations in ovarian gynandroblastoma. [Journal Article]
  • HHistopathology 2018 Apr 16
  • Wang Y, Karnezis AN, … Kommoss F
  • CONCLUSIONS: DICER1 hotspot mutation is the key-driving event in a subset of gynandroblastomas containing components of SLCT and jGCT. Gynandroblastomas composed of SLCT and jGCT may represent the morphological variants of SLCT. The molecular basis of gynandroblastoma containing a component of aGCT is different from pure aGCT. This article is protected by copyright. All rights reserved.
  • An ovarian Leydig cell tumor of ultrasound negative in a postmenopausal woman with hirsutism and hyperandrogenism: A case report. [Case Reports]
  • MMedicine (Baltimore) 2018; 97(10):e0093
  • Chen M, Zhou W, … Li C
  • CONCLUSIONS: It is common that postmenopausal androgen excess is a state of relative or absolute androgen excess originating from the adrenal gland and/or ovaries. In either case, doctors need to assess such patients and exclude relatively rare potential causes of tumors. Any woman who has hirsutism or frank evidence of markedly increased testosterone should exclude this kind of possibility of androgen producing tumors. It is possible to determine the origin of androgen hypersecretion with the severity of symptoms, the extent of androgen excess, and the relevant imaging studies. Since LCT are rare ovarian sex-cord stromal tumors, it can be beneficial for diagnosis with careful research of patient history of the defeminization followed by virilization, and a CT and MRI image.
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