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1,172 results
  • Trihexyphenidyl for dystonia in cerebral palsy. [Review]
  • CDCochrane Database Syst Rev 2018 May 15; 5:CD012430
  • Harvey AR, Baker LB, … Williams K
  • CONCLUSIONS: At present, there is insufficient evidence regarding the effectiveness of trihexyphenidyl for people with cerebral palsy for the outcomes of: change in dystonia, adverse effects, increased upper limb function and improved participation in activities of daily living. The study did not measure pain or quality of life. There is a need for larger randomised, controlled, multicentre trials that also examine the effect on pain and quality of life in order to determine the effectiveness of trihexyphenidyl for people with cerebral palsy.
  • Misuse of Trihexyphenidyl (Artane) on Réunion Island. [Journal Article]
  • JCJ Clin Psychopharmacol 2018; 38(3):250-253
  • Torrents R, Ferré JF, … Scerra S
  • CONCLUSIONS: This cohort describing the clinical characteristics of 69 patients is the largest cohort studied for THP addiction. Patients from the Centres for Addiction Prevention and Treatment were the youngest and most recently addicted, whereas general practice patients had been addicted for longer and were more socially integrated. This clinical description of THP addiction therefore enables us to identify the patients who are the most at risk, to set up an adapted care protocol.
  • Prescribing Pattern for Parkinson's Disease in Indian Community before Referral to Tertiary Center. [Journal Article]
  • CJCan J Neurol Sci 2017; 44(6):705-710
  • Surathi P, Kamble N, … Pal PK
  • CONCLUSIONS: Levodopa and trihexyphenidyl were the most commonly prescribed drugs in our patients. A higher use of trihexyphenidyl could be due to its easy availability, low cost, and better tolerability in our patients, who were relatively young at the time of onset of their disease. The choice of antiparkinsonian medications at the primary and secondary care levels in India may be inappropriate, and newer guidelines tailored to the Indian context are warranted.
  • Disabling tremor induced by long-term use of sodium valproate and lamotrigine: Case report. [Case Reports]
  • MMedicine (Baltimore) 2017; 96(47):e8711
  • He ZF, Chen J, … Wang XH
  • CONCLUSIONS: Considering the wide and long-term utilization of VPA and LTG, healthcare providers should be aware of them as a possible cause of tremor. When necessary, an attempt of discontinuing the suspected drugs should be made to confirm the diagnosis, instead of symptomatic treatment, especially when the adverse event was severe and fatal.
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