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(Arthritis, general)
14,801 results
  • TBK1/IKKE blockade inhibits mutant STING mediated inflammatory response in patient cells. [Journal Article]
  • ARArthritis Rheumatol 2017 Apr 20
  • Frémond ML, Uggenti C, … Rodero MP
  • CONCLUSIONS: Our findings demonstrate the effect of BX795 on reducing type I IFN production and IFN signaling in cells from patients with gain-of-function mutations in STING. A combined inhibition of TBK1 and IKKΕ therefore holds potential for the treatment of STING-mutated patients, and may also be relevant in other type I interferonopathies. This article is protected by copyright. All rights reserved.
  • Pilot survey of the health of Massachusetts dentists. [Journal Article]
  • JIJ Investig Clin Dent 2017 Apr 16
  • Nalliah RP, Budd A, Allareddy V
  • CONCLUSIONS: This pilot study highlights several health issues where dentists seem to have a lower incidence than the general population: asthma, depression, diabetes, hearing loss, obesity, smoking, sleep apnea, and thyroid disease. However, there are some health issues where dentists have a higher incidence than the general population: taking at least one prescription medication, gastroesophageal reflux disease, some form of cancer, back pain, neck pain, headache, osteoarthritis, rheumatic arthritis, psoriatic arthritis, and alcohol abuse.
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