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3,523 results
  • Drug-induced eosinophilic pneumonia: A review of 196 case reports. [Review]
  • MMedicine (Baltimore) 2018; 97(4):e9688
  • Bartal C, Sagy I, Barski L
  • CONCLUSIONS: AEP is a much more fulminant and severe disease than the gradual onset and slowly progressive nature of CEP. The pathogenesis of AEP and CEP remains unclear. However, there is significant clinical overlap among AEP and CEP that are associated with drug toxicity, suggesting the possibility that AEP and CEP are distinct clinical presentations that share a common pathogenic pathway.
  • Thiopurine Treatment in Ulcerative Colitis: A Critical Review of the Evidence for Current Clinical Practice. [Journal Article]
  • IBInflamm Bowel Dis 2017 Dec 19; 24(1):67-77
  • van Gennep S, de Boer NK, … Löwenberg M
  • CONCLUSIONS: All studies that investigated thiopurine treatment in UC had shortcomings, such as lack of sufficient power, no use of blinding, allowed concomitant treatment with steroids, and no endoscopy to confirm active disease at study entry or to evaluate therapeutic efficacy. Hence, current clinical practice of thiopurine treatment in UC is based on minimal and controversial evidence. This underscores the need for clinical studies with sufficient power and objective end points in order to determine efficacy of thiopurines in UC.
  • Interventions for treating collagenous colitis. [Review]
  • CDCochrane Database Syst Rev 2017 11 11; 11:CD003575
  • Kafil TS, Nguyen TM, … McDonald JW
  • CONCLUSIONS: Low quality evidence suggests that budesonide may be effective for inducing and maintaining clinical and histological response in patients with collagenous colitis. We are uncertain about the benefits and harms of therapy with bismuth subsalicylate, Boswellia serrata extract, mesalamine with or without cholestramine, prednisolone and probiotics. These agents and other therapies require further study.
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