- An Overview of Ascariasis Involvement in Gallbladder Disease: A Systematic Review of Case Reports. [Review]
- Ascaris lumbricoides is the most common type of helminth infection in humans. It affects more than one billion of the world's population. Children living in developing nations are prone to ascariasis, presenting with obstructive biliary illnesses. Migration of Ascaris worms through the major duodenal papilla to the hepatobiliary system leads to symptoms of biliary colic and complications along th…
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- Seroprevalence of Ascaris suum compared to milk spot prevalence at slaughter in Italian fattening pigs. [Journal Article]Vet Parasitol Reg Stud Reports. 2023 Jan; 37:100828.VP
- Ascaris suum is one of the most important parasites of pigs. Apart from liver condemnation due to lesions caused by migrating larvae ("milk spots"), A. suum infections can compromise weight gain, feed conversion efficacy, as well as meat quality. The true prevalence of infection depends on the diagnostic test used and is often underestimated. We compared liver inspection at slaughter with serolog…
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- Transcriptome profiling of male and female Ascaris lumbricoides reproductive tissues. [Journal Article]
- CONCLUSIONS: This study has provided comprehensive transcriptome profiles of discrete A. lumbricoides reproductive tissue samples, revealing the molecular basis of these functionally important tissues. The data generated from this study will provide fundamental knowledge on the reproductive biology of Ascaris and will inform future target identification for anti-ascariasis drugs and/or vaccines.
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- Successful Management of Biliary Ascariasis in a High-Endemic Zone and Low-Resource Setting in Ethiopia. [Case Reports]
- Ascariasis lumbricoides is a roundworm that causes one of the most common soil-transmitted helminth infections worldwide. Ascariasis is typically found in the jejunum and transmitted through the intake of Ascaris lumbricoides eggs through food and water. Initially, ascariasis can cause pulmonary symptoms during the first 6-8 weeks of ingestion and can progress to serious complications of intestin…
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- [Spatio-temporal distribution characteristics of soil-transmitted nematodiasis in Sichuan Province from 2016 to 2021]. [Journal Article]Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2022 Nov 14; 34(5):484-492.ZX
- CONCLUSIONS: The prevalence of soil-transmitted nematode infections appeared a tendency towards a decline in Sichuan Province from 2016 to 2021, which showed spatial clusters. The management of soil-transmitted nematodiasis requires to be reinforced in high-risk areas of Sichuan Province with adaptations to local epidemiological features.
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- An unusual presentation of diabetic ketoacidosis associated with ascariasis and fungal esophagitis: A case report. [Case Reports]
- CONCLUSIONS: In this case, despite the correction of metabolic acidosis, persistent nausea, vomiting and dysphagia can be a sign of esophagitis in patients with type 1 diabetes. Therefore, physicians should be aware of fungal infections associated with type 1 diabetes.
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- Intestinal Parasitic Infection and Nutritional Status in Children under Five Years Old: A Systematic Review. [Review]
- Intestinal parasitic infections are common infectious diseases causing many health problems and impaired growth and physical development.. Children under five years old are the most vulnerable to infections, due to their immature immunity and feeding and exploratory behaviours. This systematic review aimed to assess the relationship between intestinal parasitic infections and undernutrition among…
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- Effect of probiotics on the intestinal microbiota of patients with giardiasis and ascariasis. [Journal Article]
- Recently, many cases of mixed invasion by Giardia and ascarids have been registered. Gastrointestinal lesions in patients are often accompanied by dysbiotic changes. The aim was to study the effect of probiotics containing Saccharomyces bouvardias CNCM I-745 in the complex therapy of patients with giardiasis, ascariasis, and mixed invasion. 90 patients with giardiasis, ascariasis and mixed invasi…
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- Global prevalence of Ascaris infection in humans (2010-2021): a systematic review and meta-analysis. [Review]
- CONCLUSIONS: Our findings indicate that, despite a renewed commitment by some communities or authorities to control ascariasis, a substantial portion of the world's human population (> 0.7 billion) is infected with Ascaris. Despite the clinical and socioeconomic importance of ascariasis, many past routine surveys did not assess the intensity of Ascaris infection in people. We propose that the present findings might stimulate the development of customised strategies for the improved control and prevention of Ascaris infection worldwide.
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- Modulation of the porcine intestinal microbiota in the course of Ascaris suum infection. [Journal Article]
- CONCLUSIONS: These different patterns may have important implications regarding the comparability of experimental infections with natural scenarios characterized by continuous exposure, and should be confirmed by further studies.
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- A reverse vaccinology approach identifies putative vaccination targets in the zoonotic nematode Ascaris. [Journal Article]
- Ascariasis is the most prevalent helminthic disease affecting both humans and pigs and is caused by the roundworms Ascaris lumbricoides and Ascaris suum. While preventive chemotherapy continues to be the most common control method, recent reports of anthelminthic resistance highlight the need for development of a vaccine against ascariasis. The aim of this study was to use a reverse vaccinology a…
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- Fatal Undernutrition Due to Severe Gastrointestinal Ascariasis in an Adult. [Journal Article]Am J Forensic Med Pathol. 2022 12 01; 43(4):e101-e104.AJ
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- Gut bacteriome and metabolome of Ascaris lumbricoides in patients. [Journal Article]
- The most frequent intestinal helminth infections in humans are attributed to Ascaris lumbricoides, and there are concerns over the anthelminthic resistance of this species. The gut microbiota has essential roles in host physiology. Therefore, discovering host-parasite-microbiota interactions could help develop alternative helminthiasis treatments. Additionally, these interactions are modulated by…
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- Pharmacokinetics and therapeutic efficacy of levamisole in Ascaridia galli experimentally infected ducks. [Journal Article]Vet Parasitol. 2022 Dec; 312:109838.VP
- This study investigated the pharmacokinetics and therapeutic efficacy of levamisole (LVS) after intravenous (i.v.) and oral administrations to healthy and Ascaridia galli-infected ducks by developing an infection model. Twenty-four two-week old ducklings were experimentally infected with A. galli. The ducks were monitored for the development of infection and after 8 weeks they were administered w…
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- Aqueous extract of Parkia biglobosa (Jacq.) R. Br. (Fabaceae) exerts antiepileptogenic, anti-amnesic, and anxiolytic-like effects in mice via mechanisms involving antioxidant and anti-inflammatory pathways. [Journal Article]
- Parkia biglobosa (Jacq.) R. Br. (Fabaceae) is a widely distributed tree, used in traditional medicine to treat amebiasis, hookworm infection, ascariasis, asthma, sterility, dental pain, headaches, cardiac disorders, and epilepsy. To date, no study on the effect of an aqueous extract of P. biglobosa on epileptogenesis and associated neuropsychiatric disorders has been undertaken. Therefore, this s…
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- "Worm within worm": acute appendicitis containing an adult Ascaris lumbricoïdes. [Case Reports]
- Appendicitis is the first etiology for abdominal surgical emergency. Ascariasis is the most common helminth infection in tropical countries where it is endemic. The ability of intestinal helminths to wander through the digestive system means that it can end up in the appendix lumen and lead to appendicitis by luminal obstruction. However, this presentation is still rarely described in the literat…
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- Prevalence of Ascaris lumbricoides infections among elementary school children and associated risk factors from Southern Ethiopia. [Journal Article]
- Intestinal parasitic infections are distributed virtually throughout the world, with high prevalence rates in tropical and sub-tropical parts of the world as well as in Ethiopia. Children between age groups of 5-10 years are at the highest risk of infection. The intestinal nematode Ascaris lumbricoides infects approximately 25% of the world's population annually. Hence, this study was the first a…
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- Bioaccessibility and oral immunization efficacy of a chimeric protein vaccine against Ascaris suum. [Journal Article]Microbes Infect. 2022 Sep 06; 25(3):105042.MI
- Human ascariasis has been characterized as the most prevalent neglected tropical disease worldwide. There is an urgent need for search to alternative prevention and control methods for ascariasis. Here we aimed to establish a protocol of oral immunization with a previously described chimera protein capable of resist through digestion and induce mucous protection against Ascaris suum infection. Mi…
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- Schistosoma mansoni and soil-transmitted helminths among schoolchildren in An-Nadirah District, Ibb Governorate, Yemen after a decade of preventive chemotherapy. [Journal Article]
- The Ministry of Public Health in Yemen continues the implementation of school and community-based preventive chemotherapy with praziquantel and albendazole for the control and elimination of schistosomiasis and soil-transmitted helminths (STH). The latest remapping to update the distribution of schistosomiasis and STH was conducted seven years ago. This study aimed to estimate the prevalence, int…
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- StatPearls: Trichuris Trichiura [BOOK]StatPearls. StatPearls Publishing: Treasure Island (FL)BOOK
- Trichuris trichiura, also known as the human whipworm, is a roundworm that causes trichuriasis in humans. It is referred to as the whipworm because it looks like a whip with wide handles at the posterior end. The whipworm has a narrow anterior esophagus and a thick posterior anus. The worms are usually pink and attach to the host via the slender anterior end. The size of these worms varies from 3…
- Assessing the impact of Ascariasis and Trichuriasis on weight gain using a porcine model. [Journal Article]
- CONCLUSIONS: Overall this study has demonstrated a negative association between STH and weight gain in growing pigs but also that T. suis infection may be more detrimental that A. suum on growth.
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- Risk of acquiring Ascaris lumbricoides infection in an endemically infected rural community in Venezuela. [Journal Article]
- Soil-transmitted helminths, such as Ascaris lumbricoides, are the most prevalent parasites globally. Optimal anthelmintic treatment for A. lumbricoides in endemically infected communities is challenged by several host-related and environmental factors influencing infection acquisition. We assessed the risk of A. lumbricoides (re)infection after treatment in a Venezuelan rural community. Individua…
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- Efficacy of triple dose albendazole treatment for soil-transmitted helminth infections. [Journal Article]
- In Malaysia, soil-transmitted helminth (STH) infections still persist among indigenous communities. In the past, local studies have focused mostly on epidemiologic aspects of STH infections with a scarcity of information on the efficacy of deworming treatment. The present study consisted of 2 phases: a cross-sectional phase on current epidemiological status and risk factors of STH infections and …
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- Case Report: Laparoscopic Management of Acute Appendicitis Resulting from Ascaris lumbricoides. [Case Reports]
- Appendicitis is one of the most common conditions that leads to an acute abdomen. Surgical management is the gold standard for therapy. The main cause of appendicitis is an obstruction in the appendicular lumen. Intestinal ascariasis infection is undoubtedly one of the least frequent. We present a female patient with acute appendicitis resulting from Ascaris lumbricoides as an incidental intraope…
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- Risk Factors, Clinical Features, and Outcomes of Acute Pancreatitis in Children in Endemic Zone of Ascariasis in Eastern Bihar: A Hospital-Based Study. [Journal Article]
- Objective This study aims to describe the etiology, clinical features, and outcomes of acute pancreatitis (AP) in children in an endemic area of hepatobiliary ascariasis. Methods This retrospective observational study included acute pancreatitis (AP) patients in the age group of 2-15 years from January 2019 to January 2022. Demographic profile, risk factors, clinical features, laboratory imaging,…
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- StatPearls: Ascariasis [BOOK]StatPearls. StatPearls Publishing: Treasure Island (FL)BOOK
- Approximately one billion people worldwide are infected with Ascaris lumbricoides, and more than 60,000 people die from the disease annually. It affects mostly tropical and subtropical countries around the world, and it is frequently documented in Sub-Saharan Africa, Latin America, China, and East Asia. Unfortunately, it is a neglected tropical disease that causes an estimated loss of 1.2 to 1.5 …
- Genetic diversity and identity of Ascaris worms from human and pig hosts in Thailand. [Journal Article]Vet Parasitol Reg Stud Reports. 2022 08; 33:100752.VP
- Ascaris roundworms are of public health and socio-economic importance worldwide. They are conventionally attributed to two taxa - A. lumbricoides infecting principally human and A. suum infecting principally pig. Phylogenomic analysis has revealed that Ascaris worms from both human and pig are represented in Clades A and B. A recent study indicates that the Ascaris worms from human and pig in Tha…
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- [Ascaris lumbricoides-induced pancreatic lesion]. [Journal Article]Khirurgiia (Mosk). 2022K
- Ascaris lumbricoides is nematode localized in human small bowel in most cases. This nematode is capable for migration. Pancreatitis is one of the most common surgical diseases. One of the causes of this pancreatitis may be migration of Ascaris lumbricoides from small bowel through the major duodenal papilla to the pancreatic ducts. This migration is provided by complex of morphological and functi…
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