- Biliary parascarosis in a foal. [Case Reports]Vet Med Sci. 2023 Feb 01 [Online ahead of print]VM
- Migration of Ascaris lumbricoides through the papilla of Vater in humans, and entry into the biliary tree, is well-recognised. Ascaris suum and Toxocara vitulorum have been recovered from the liver of swine and buffalo. We necropsied a Persian Kurdish filly at age 6 months, weighing ∼100 kg. Death evidently was caused by oleander (Nerium oleander) intoxication. An 8-cm adult male Parascaris was f…
- Publisher Full Text (DOI)
- Intestinal Parasitic Infection Among Rural Schoolchildren in Taiz, Yemen: School-based Assessment of The Prevalence and Associated Risk Factors. [Journal Article]
- Yemen is an underdeveloped country plagued by poverty, disease, and social conflicts. Furthermore, most of the population lives in rural areas and is vulnerable to intestinal parasite infections (IPI). School-based cross-sectional studies were conducted between 1 February and 31 March 2019 among schoolchildren in rural communities in the Sabir Almawadim and Almawasit districts of Taiz, southwest …
- PMC Free PDF
- Intestinal Parasitic Infections and Associated Risk Factors among Food Handlers of Food and Drinking Establishments in Woldia Town, North-East Ethiopia: A Cross-Sectional Study. [Journal Article]
- CONCLUSIONS: This study revealed a relatively high prevalence of intestinal parasites among food handlers in Woldia town. Strict and standard hygienic and sanitary practices should be implemented by food handlers. Moreover, food handlers should be screened for intestinal parasitic infection, and health education should be given periodically.
- PMC Free PDF
- Soil-Transmitted Helminth Infections among Antenatal Women in Primary Care Settings in Southern India: Prevalence, Associated Factors and Effect of Anti-Helminthic Treatment. [Journal Article]
- Community-based studies from India on prevalence of soil-transmitted helminth (STH) infections have reported estimates as high as 50% in children. However, prevalence estimates during pregnancy in India are lacking. We aimed to describe the burden, associated factors of STH and cure rate after deworming in primary care settings. Pregnant women were recruited from four urban and five rural centers…
- PMC Free PDF
- Mono-Parasitic and Poly-Parasitic Intestinal Infections among Children Aged 36-45 Months in East Nusa Tenggara, Indonesia. [Journal Article]
- The prevalence of intestinal parasitic infection remains high in developing countries, especially because of geographic and socio-demographic factors. This study aimed to evaluate intestinal parasitic infection, as well as its risk factors, among children aged 36-45 months in a rural area (North Kodi) and an urban area (Kupang) of East Nusa Tenggara, Indonesia. Anthropometry, socio-demographic fa…
- PMC Free PDF
- Helminth species-specific effects on IFN-γ producing T cells during active and latent tuberculosis. [Journal Article]
- CONCLUSIONS: We found a reduction in IFN-γ producing T cells by helminth coinfection which was restored following anti-helminthic treatment. This reduction was helminth species-dependent in an exploratory sub-analysis and correlated to increased disease severity.
- PMC Free PDF
- Ascaris induced acute pancreatitis in paediatric population - a case series. [Journal Article]J Pak Med Assoc. 2022 Oct; 72(10):2090-2092.JP
- The most common helminthic parasitic infection inhabiting human intestine is Ascaris lumbricoides (AL). Being the largest of the helminthic family, it infects almost one billion people worldwide, but any information about local population is unavailable especially in children. When patients present with abdominal pain, having ascaris induced pancreatitis never meets the differential diagnosis lis…
- Publisher Full Text (DOI)
- An Overview of Ascariasis Involvement in Gallbladder Disease: A Systematic Review of Case Reports. [Review]
- Ascaris lumbricoides is the most common type of helminth infection in humans. It affects more than one billion of the world's population. Children living in developing nations are prone to ascariasis, presenting with obstructive biliary illnesses. Migration of Ascaris worms through the major duodenal papilla to the hepatobiliary system leads to symptoms of biliary colic and complications along th…
- PMC Free PDF
- High Prevalence of Hookworm Species and Associated Factors among Soil-Transmitted Helminth-Infected Household Contacts in Burie Zuria District, Northwest Ethiopia: A Community-Based Cross-Sectional Study. [Journal Article]
- CONCLUSIONS: A high prevalence of hookworms was found in the study area, where the majority of the study participants were adults. This finding may provide a basis for revising the school-based deworming programs that exclude the adult population. Public health interventions like accessing latrines, health education, and deworming programs should be regularly implemented for all age groups in the areas.
- PMC Free PDF
- Gut Parasites of medical importance harboured by Musca domestica in Calabar, Nigeria. [Journal Article]
- CONCLUSIONS: This study has confirmed M. domestica in Calabar as a mechanical carrier of potential pathogenic gut parasites, especially in the insanitary areas, with E. histolytica/dispar being the most frequently encountered. Effective control of flies' population in the human and animal habitats and increased public awareness on their health hazards are recommended.
- PMC Free PDF
- Prevalence and Associated Risk Factors of Soil-Transmitted Helminth Infections among Schoolchildren around Lake Tana, Northwest Ethiopia. [Journal Article]J Parasitol Res. 2022; 2022:4603638.JP
- CONCLUSIONS: The present study showed that STHs were common among schoolchildren around Lake Tana. Therefore, education on personal and environmental hygiene should be taken into account to reduce the prevalence of STH infection in the study area.
- PMC Free PDF
- Intestinal parasitic infections and risk factors among the population in Cambodia. [Journal Article]Trop Biomed. 2022 Dec 01; 39(4):539-546.TB
- Many species of helminths and protozoa caused intestinal parasitic infections (IPIs). It belongs to neglected tropical diseases (NTDs) and remains a major public health problem in several Southeast Asian countries. The present study aimed to investigate the prevalence of IPIs and associated risk factors among the population in Kratie Province in northeastern Cambodia and Phnom Penh is the capital…
- Publisher Full Text (DOI)
- Soil-transmitted helminthic vaccines: Where are we now? [Review]Acta Trop. 2022 Dec 29; 239:106796.AT
- It has been tested and proven that vaccination is still the best strategy to combat infectious diseases. However, to date, there are still no vaccines against human soil-transmitted helminthic diseases, despite their high prevalence globally, particularly in developing countries and rural areas with tropical climates and poor sanitation. The development of vaccines against helminths is riddled wi…
- Publisher Full Text (DOI)
- Precision and geographical prevalence mapping of schistosomiasis and soil-transmitted helminthiasis among school-aged children in selected districts of north-western Tanzania. [Journal Article]
- CONCLUSIONS: The data reported here show that schistosomiasis and STH are widely distributed around Lake Victoria. In most of the schools where schistosomiasis and STH occurred the transmission thresholds were low. These data are important and need to be taken into consideration when decisions are made on the implementation of the next round of mass chemotherapies for schistosomiasis and STH in Tanzania.
- PMC Free PDF
- Multiple overlapping risk factors for childhood wheeze among children in Benin. [Journal Article]
- CONCLUSIONS: Children infected with A. lumbricoides appear to be at elevated risk of wheeze. Deworming may be an important intervention to reduce these symptoms. Improving cooking methods to reduce household air pollution, modifying dietary habits to avoid overweight, and keeping animals out of the house are all additional measures that could also contribute to reducing childrens' risk of wheeze. Policymakers in LMIC should consider tailoring public health measures to reflect the importance of these different risk factors.
- PMC Free PDF
- Trends of intestinal parasites among the patients attended at Yabelo General Hospital, Borena Zone, Southern Ethiopia. [Journal Article]
- CONCLUSIONS: The prevalence of IPI was high among patients seen at Yabelo General Hospital. The analysis showed that the prevalence declined from 2019 to 2021. To sustain the decrease in prevalence, all intestinal parasite prevention measures should be continuously exercised in the area.
- PMC Free PDF
- Assessment of cetyl-trimethyl-ammonium bromide (CTAB) based method for the extraction of soil-transmitted helminth DNAs from stools for molecular dagnostic of soil-transmitted helminthiasis. [Journal Article]J Microbiol Methods. 2023 Jan; 204:106661.JM
- Although several protocols were developed to extract DNA for soil-transmitted helminthiasis diagnostic, amplifying these extracts remains challenging due to DNA polymerase inhibitors. This study aimed to assess a DNA extraction method for efficient detection of soil-transmitted helminth species by determining stool mass and the type of DNA polymerase that can be used for this extraction method. F…
- Publisher Full Text (DOI)
- The turkey ascarid, Ascaridia dissimilis, as a model genetic system. [Journal Article]Int J Parasitol. 2022 Dec 19 [Online ahead of print]IJ
- Parasitic nematodes cause significant effects on humans each year, with the most prevalent being Ascaris lumbricoides. Benzimidazoles (BZ) are the most widely used anthelmintic drug in humans, and although the biology of resistance to this drug class is understood in some species, resistance is poorly characterized in ascarids. Models such as Caenorhabditis elegans were essential in developing ou…
- Publisher Full Text (DOI)
- Transcriptome profiling of male and female Ascaris lumbricoides reproductive tissues. [Journal Article]
- CONCLUSIONS: This study has provided comprehensive transcriptome profiles of discrete A. lumbricoides reproductive tissue samples, revealing the molecular basis of these functionally important tissues. The data generated from this study will provide fundamental knowledge on the reproductive biology of Ascaris and will inform future target identification for anti-ascariasis drugs and/or vaccines.
- PMC Free PDF
- Successful Management of Biliary Ascariasis in a High-Endemic Zone and Low-Resource Setting in Ethiopia. [Case Reports]
- Ascariasis lumbricoides is a roundworm that causes one of the most common soil-transmitted helminth infections worldwide. Ascariasis is typically found in the jejunum and transmitted through the intake of Ascaris lumbricoides eggs through food and water. Initially, ascariasis can cause pulmonary symptoms during the first 6-8 weeks of ingestion and can progress to serious complications of intestin…
- PMC Free PDF
- Anaemia and Nutritional Status during HIV and Helminth Coinfection among Adults in South Africa. [Journal Article]
- Sub-Saharan Africa is burdened with helminthiasis and HIV/AIDS, and there is a significant overlap between these infections. However, little is known about the extent of anaemia and malnutrition in HIV/AIDS and helminth coinfected adults. The study investigated the anaemia profiles and nutritional status of HIV and helminth coinfected adult South Africans. Stool samples were collected from partic…
- PMC Free PDF
- Prevalence and Associated Risk Factors of Intestinal Parasitic Infections among Patients Visiting a Referral Hospital in Tehran Province, Iran. [Journal Article]
- CONCLUSIONS: The prevalence of IPIs among the patients who are immunocompromised was significantly higher than immunocompetent patients (P< 0.05). Periodic stool examinations for screening of IPIs should be included as a part of routine medical check-up in these patients.
- PMC Free PDF
- The survey of soil-transmitted helminth species abundance in Slovakia with an emphasis on parameters important for their distribution. [Journal Article]
- Soil-transmitted helminths (STH) can be easily dispensable in socially disadvantaged groups. The Roma people represent the group most at risk in Slovakia. This study aimed to investigate the occurrence of STH infections in minorities living with animals under low hygienic conditions and on contaminated soil. Subsequently, we identified the risk assessment factors of the STH transmissions based on…
- PMC Free PDF
- [Spatio-temporal distribution characteristics of soil-transmitted nematodiasis in Sichuan Province from 2016 to 2021]. [Journal Article]Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2022 Nov 14; 34(5):484-492.ZX
- CONCLUSIONS: The prevalence of soil-transmitted nematode infections appeared a tendency towards a decline in Sichuan Province from 2016 to 2021, which showed spatial clusters. The management of soil-transmitted nematodiasis requires to be reinforced in high-risk areas of Sichuan Province with adaptations to local epidemiological features.
- Publisher Full Text (DOI)
- Intestinal Parasitic Infections, Treatment and Associated Factors among Pregnant Women in Sao Tome and Principe: A Cross-Sectional Study. [Journal Article]
- CONCLUSIONS: This study highlights the IPI burden, associated factors, and missing treatment opportunities among pregnant women with STP. This study is a useful tool for policymakers in STP to enhance the health of women and their unborn babies.
- PMC Free PDF
- Intestinal Parasite Infections and Associated Risk Factors among Pre-School Aged Children in Kibera Informal Settlement, Nairobi, Kenya. [Journal Article]
- CONCLUSIONS: The study found both helminth and protozoan parasites to be prevalent among pre-school aged children in Kibera. Intervention measures including education on the improvement of hygiene and health, socio-economic conditions, sanitation, and provision of safe drinking water could reduce the prevalence of these infections.
- PMC Free PDF
- Intestinal Helminth Infections in Ghanaian Children from the Ashanti Region between 2007 and 2008-A Retrospective Cross-Sectional Real-Time PCR-Based Assessment. [Journal Article]
- In spite of ongoing eradication programs, helminth infections are still a medical issue in Ghana. For follow-up assessments on the decline of regional helminth infections, historic baseline prevalence values obtained with standardized diagnostic procedures can be helpful. In this retrospective cross-sectional study, real-time PCR targeting the nematodes Ancylostoma spp. (ITS2), Ascaris lumbricoid…
- PMC Free PDF
- Intestinal Parasitic Infection and Nutritional Status in Children under Five Years Old: A Systematic Review. [Review]
- Intestinal parasitic infections are common infectious diseases causing many health problems and impaired growth and physical development.. Children under five years old are the most vulnerable to infections, due to their immature immunity and feeding and exploratory behaviours. This systematic review aimed to assess the relationship between intestinal parasitic infections and undernutrition among…
- PMC Free PDF
- A reverse vaccinology approach identifies putative vaccination targets in the zoonotic nematode Ascaris. [Journal Article]
- Ascariasis is the most prevalent helminthic disease affecting both humans and pigs and is caused by the roundworms Ascaris lumbricoides and Ascaris suum. While preventive chemotherapy continues to be the most common control method, recent reports of anthelminthic resistance highlight the need for development of a vaccine against ascariasis. The aim of this study was to use a reverse vaccinology a…
- PMC Free PDF
- Gut bacteriome and metabolome of Ascaris lumbricoides in patients. [Journal Article]
- The most frequent intestinal helminth infections in humans are attributed to Ascaris lumbricoides, and there are concerns over the anthelminthic resistance of this species. The gut microbiota has essential roles in host physiology. Therefore, discovering host-parasite-microbiota interactions could help develop alternative helminthiasis treatments. Additionally, these interactions are modulated by…
- PMC Free PDF