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(Aspir Low)
73,016 results
  • Effect of colchicine and aspirin given together in patients with moderate COVID-19. [Journal Article]
    Contemp Clin Trials Commun. 2023 Jan 21 [Online ahead of print]Sunil Naik K, Andhalkar N, Pendse S
  • CONCLUSIONS: It was evident from CT scan scores that the treatment group has shown significant improvement in the reduction of inflammation and other COVID-19 symptoms as compared to the control group. The fall in Ferritin, Hs-CRP and D-Dimer level after treatment were indicative of improvement in internal inflammatory response of body in COVID-19 disease. As increased troponin levels indicate some degree of heart damage, the fall in troponin levels indicated that test treatment improved heart health in COVID-19 patients.
  • Pharmacokinetic and Pharmacodynamic Herb-Drug Interactions of Common Over-the-Counter Pain Medications. [Review]
    Biomed Chromatogr. 2023 Jan 29 [Online ahead of print]Sun CK, Tsai TH
  • Pain is one of the most common reasons for seeking medical intervention, and self-medication with over-the-counter medications and/or traditional herbal remedies has become increasingly popular. In this review, original articles on understanding possible herb-drug interaction between traditional herbs and four major pain medication: acetaminophen, aspirin, ibuprofen, and naproxen were compiled an…
  • Antithrombotic treatment after stroke due to intracerebral haemorrhage. [Review]
    Cochrane Database Syst Rev. 2023 Jan 26; 1:CD012144.Cochrane A, Chen C, … Al-Shahi Salman R
  • CONCLUSIONS: We did not identify beneficial or hazardous effects of short-term prophylactic dose parenteral anticoagulation and long-term oral antiplatelet therapy after ICH on important outcomes. Although there was a significant reduction in MACE and all major occlusive vascular events after long-term treatment with therapeutic dose oral anticoagulation for atrial fibrillation after ICH, the pooled estimates were imprecise, the certainty of evidence was only moderate, and effects on other important outcomes were uncertain. Large RCTs with a low risk of bias are required to resolve the ongoing dilemmas about antithrombotic treatment after ICH.
  • Thromboprophylaxis in Patients With Fontan Circulation. [Journal Article]
    J Am Coll Cardiol. 2023 Jan 31; 81(4):374-389.Van den Eynde J, Possner M, … Alsaied T
  • CONCLUSIONS: Aspirin, warfarin, and NOAC are associated with lower risk of thromboembolic events. Recognizing the limited number of patients and heterogeneity of studies using NOACs, the results support the safety and efficacy of NOACs in patients with a Fontan circulation.
  • Intravenous immunoglobulin for the treatment of Kawasaki disease. [Review]
    Cochrane Database Syst Rev. 2023 Jan 25; 1:CD014884.Broderick C, Kobayashi S, … Kobayashi T
  • CONCLUSIONS: The included RCTs investigated a variety of comparisons, and the small number of events observed during the study periods limited detection of effects. The certainty of the evidence ranged from moderate to very low due to concerns related to risk of bias, imprecision, and inconsistency. The available evidence indicated that high-dose IVIG regimens are probably associated with a reduced risk of CAA formation compared to ASA or medium- or low-dose IVIG regimens. There were no clinically significant differences in incidence of adverse effects, which suggests there is little concern about the safety of IVIG. Compared to ASA, high-dose IVIG probably reduced the duration of fever, but there was little or no difference detected in the need for additional treatment. Compared to medium- or low-dose IVIG, there may be reduced duration of fever and reduced need for additional treatment. We were unable to draw any conclusions regarding acute coronary syndromes, mortality, or length of hospital stay, or for the comparison IVIG versus prednisolone. Our findings are in keeping with current guideline recommendations and evidence from long-term epidemiology studies.
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