Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.
(Asplenia and infection risk)
241 results
  • [Splenic dysfunction in sickle cell disease: An update]. [Review]
    Rev Med Interne. 2023 Jan 27 [Online ahead of print]Tennenbaum J, Volle G, … Arlet JB
  • The spleen filters blood cells and contributes to the immune defense. The red pulp clears the blood from altered red blood cells via its unique microcirculatory network ; while the white pulp is a secondary lymphoid organ, directly connected to the bloodstream, whose specificity is the defense against encapsulated bacteria through the production of "natural" IgM in the marginal zone. Various heal…
  • StatPearls: Asplenia [BOOK]
    StatPearls. StatPearls Publishing: Treasure Island (FL)AshorobiDamilolaDNassau University Medical CenterFernandezRobertoRNassau University Medical CenterBOOK
  • Asplenia means the absence of a spleen. Asplenia can occur in a variety of clinical settings, and it can refer to an anatomic absence of the spleen or functional asplenia secondary to a variety of disease states. The spleen is one of the primary extramedullary lymphoid organs. It is located in the left upper quadrant of the abdomen. Normally, the spleen is not palpable on physical exam and measur…
  • Asplenia and spleen hypofunction. [Review]
    Nat Rev Dis Primers. 2022 11 03; 8(1):71.Lenti MV, Luu S, … Di Sabatino A
  • Asplenia (the congenital or acquired absence of the spleen) and hyposplenism (defective spleen function) are common causes of morbidity and mortality. The spleen is a secondary lymphoid organ that is responsible for the regulation of immune responses and blood filtration. Hence, asplenia or hyposplenism increases susceptibility to severe and invasive infections, especially those sustained by enca…
  • StatPearls: Secondary Thrombocytosis [BOOK]
    StatPearls. StatPearls Publishing: Treasure Island (FL)RokkamVenkata R.VRBanner UniversityKotagiriRajeshRBanner University Medical Center, TucsonBOOK
  • Platelets are a component of blood produced in the bone marrow that plays a vital role in the blood clotting process. The normal platelet count in adults and children is 150,000/microL to 450,000/microL (150 to 450 x 10/L), but the normal range may vary in different clinical laboratories. Thrombocytosis is a condition where the platelet count exceeds 450,000/μl.[1] It is also referred to as throm…
  • Fatal Babesiosis in an Immunocompetent Patient. [Case Reports]
    R I Med J (2013). 2022 08 01; 105(6):20-23.Selig T, Ilyas S, … Lee J
  • Human babesiosis is an emerging infectious disease with a progressively rising number of cases in the Northeast over the last few decades. We report a case of fatal babesiosis in a 48-year-old male without significant risk factors for a severe presentation. Clinicians should be aware that even in patients without the classic risk factors of asplenia, advanced age, and immunocompromised status for…
  • Capnocytophaga canimorsus Bloodstream Infection Associated with an Urticarial Exanthem. [Case Reports]
    Case Rep Infect Dis. 2021; 2021:9932170.Goetzinger JC, LaGrow AL, … Thind SK
  • Background. Capnocytophaga canimorsus is a fastidious, slow-growing, Gram-negative rod that is a commensal bacterium in normal gingival flora of canine and feline species. Infection with the organism may cause disease ranging from flu-like symptoms to disseminated intravascular coagulation (DIC), fulminant sepsis, meningitis, and endocarditis with an overall fatality rate of 6-26%. Risk factors f…
  • Pulmonary complications of sickle cell disease: a narrative clinical review. [Review]
    Adv Respir Med. 2021; 89(2):173-187.Pervaiz A, El-Baba F, … Soubani A
  • Sickle cell disease (SCD) is associated with vaso-occlusive episodes that affect different organs. Pulmonary involvement is a major cause of morbidity and mortality in this patient population. We performed a literature search in the PubMed database for articles addressing SCD and pulmonary diseases. Acute chest syndrome is defined as a new radiodensity on chest radiograph imaging with a history c…
  • A Review of Vaccinations in Adult Patients with Secondary Immunodeficiency. [Review]
    Infect Dis Ther. 2021 Jun; 10(2):637-661.Righi E, Gallo T, … Tacconelli E
  • Vaccine-preventable diseases and their related complications are associated with increased morbidity and mortality in patients with altered immunocompetence. Optimised immunisation in this patient population is challenging because of limited data from vaccine trials, suboptimal vaccine efficacy and safety concerns. Reliable efficacy data are lacking among patients with altered immunocompetence, a…
New Search Next