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36,436 results
  • Clinical and Molecular Recursive Partitioning Analysis of High-grade Glioma Treated With IMRT. [Journal Article]
  • AJAm J Clin Oncol 2018 Jun 14
  • Sutera P, Kalash R, … Heron DE
  • CONCLUSIONS: The RTOG-RPA retains partial prognostic significance, however, should be updated to reflect recent advancements. This series represents a large RPA analyzing both clinical and genetic factors and generated 7 distinct survival classes. Further assessment of patients with fully available genetic markers generated 5 distinct survival classes. These survival classifications need to be validated by a prospective data set and compared against the RTOG-RPA to determine whether they provide improved prognostic power.
  • Circulating serum oncologic miRNA in pediatric juvenile pilocytic astrocytoma patients predicts mural nodule volume. [Journal Article]
  • ANActa Neurochir (Wien) 2018 Jun 18
  • Bookland M, Tang-Schomer M, … Kolmakova A
  • CONCLUSIONS: In this small pilot study, pediatric juvenile pilocytic astrocytoma patients had significant elevations in serum miR-21, miR-15b, miR-23a, and miR-146b levels that do not appear to be driven by hydrocephalus or local distortion of the intracranial contents. These alterations correlate with solid tumor component volume and reverse with complete tumor resection, suggesting that this serum miRNA profile may delineate biomarkers for screening and tracking juvenile pilocytic astrocytoma patients. Additional studies, with a larger cohort, are needed to verify these results.
  • Endoscopy in Temporal lobe Glioma and Metastasis resection: Is there a Role? [Journal Article]
  • WNWorld Neurosurg 2018 Jun 11
  • Ma R, Coulter CA, … Plaha P
  • CONCLUSIONS: The endoscope has a role in temporal lobe intraparenchymal tumor surgery especially in three illustrative scenarios: 1) medial temporal, parahippocampal-gyrus low-grade non-enhancing gliomas, 2) subcortical high-grade glioma and metastases medial to the sagittal stratum and 3) recurrent gliomas with cystic resection cavity. The endoscope offers a safe and a useful adjunct to the surgeons' armamentarium in brain tumor surgery. A minimally invasive approach also reduces surgical morbidity and length of stay.
  • Age and surgical outcome of low-grade glioma in Sweden. [Journal Article]
  • ANActa Neurol Scand 2018 Jun 13
  • Corell A, Carstam L, … Jakola AS
  • CONCLUSIONS: In general, older patients with LGG have several unfavorable prognostic factors compared with younger patients but seem to tolerate surgery in a comparable fashion. However, more neurological deficits were observed following resections in elderly. Our data further support a cutoff at 50 years rather than 40 years for selection of high-risk patients.
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