- Invasive electrophysiological testing to predict and guide permanent pacemaker implantation after transcatheter aortic valve implantation: A meta-analysis. [Journal Article]Heart Rhythm O2. 2023 Jan; 4(1):24-33.HR
- CONCLUSIONS: Selective EPS testing may assist in the risk stratification of post-TAVI HG-AVB and in the guidance of PPM implantation, especially in patients with equivocal PPM indications post-TAVI.
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- Case report: Left ventricular perforation caused by right ventricular pacemaker lead. [Case Reports]Front Cardiovasc Med. 2022; 9:1089694.FC
- Perforation of the interventricular septum and left ventricular (LV) free wall by a right ventricular (RV) lead is an extremely rare and potentially life-threatening complication. In this case report, we discussed the diagnosis and management of a very unusual complication of pacemaker (PM) implantation, i.e., LV perforation brought on by an RV pacing lead.
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- Conduction mapping during complex congenital heart surgery: Creating a predictive model of conduction anatomy. [Journal Article]J Thorac Cardiovasc Surg. 2022 Dec 13 [Online ahead of print]JT
- CONCLUSIONS: The precise anatomic location of the conduction system in patients with complex congenital heart defects can be difficult for the surgeon to accurately predict. Intraoperative conduction mapping enables localization of the His bundle and adds to our understanding of the anatomic factors associated with conduction location. Predictive modeling of conduction anatomy may build on what is already known about the conduction system and help surgeons to better anticipate conduction location preoperatively and intraoperatively.
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- The anatomical basis of third-degree atrioventricular block in dogs with atrioventricular valve endocardiosis. [Journal Article]J Comp Pathol. 2023 Jan 27; 201:63-69.JC
- The cardiac conduction system was examined histologically in 13 canine cases of atrioventricular (AV) valve endocardiosis with third-degree AV block. In all cases, gross examination revealed marked thickening and distortion of the base of the central fibrous body (CFB) and varying degrees of endocardial thickening of the upper portion of the ventricular septum (VS) as well as marked thickening of…
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- Reduction in Junctophilin 2 Expression in Cardiac Nodal Tissue Results in Intracellular Calcium-Driven Increase in Nodal Cell Automaticity. [Journal Article]Circ Arrhythm Electrophysiol. 2023 Jan 27 [Online ahead of print]CA
- CONCLUSIONS: Nodal-specific Jph2 knockdown causes increased nodal automaticity through increased Ca2+ leak from intracellular stores. Dysregulated intracellular Ca2+ underlies nodal arrhythmogenesis in this mouse model.
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- Ventriculoatrial Block and His-His Changes During Supraventricular Tachycardia: Diagnostic and Mechanistic Implications. [Case Reports]
- Supraventricular tachycardia (SVT) with ventriculoatrial (VA) block can represent a diagnostic challenge. We present a case of SVT where His-His interval shortening was repeatedly observed during episodes of VA block. This novel observation is more diagnostically suggestive of atrioventricular nodal re-entrant tachycardia, as opposed to orthodromic re-entry using a nodofascicular or nodoventricul…
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- Cardiac Resynchronization Therapy Improves Outcomes in Patients With Intraventricular Conduction Delay But Not Right Bundle Branch Block: A Patient-Level Meta-Analysis of Randomized Controlled Trials. [Journal Article]Circulation. 2023 Jan 26 [Online ahead of print]Circ
- CONCLUSIONS: CRT is associated with reduced HFH or death in patients with QRS ≥150 ms and LBBB or IVCD, but not for those with RBBB. Aggregating RBBB and IVCD into a single "non-LBBB" category when selecting patients for CRT should be reconsidered.
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- Increased reliance on coronary perfusion for cardiorespiratory performance in seawater-acclimated rainbow trout. [Journal Article]J Exp Biol. 2023 Jan 26 [Online ahead of print]JE
- Salmonid ventricles are composed of spongy and compact myocardium, the latter being perfused via a coronary circulation. Rainbow trout (Oncorhynchus mykiss) acclimated to sea water have higher proportions of compact myocardium and display stroke volume-mediated elevations in resting cardiac output relative to freshwater-acclimated trout, likely to meet the higher metabolic needs of osmoregulatory…
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- The prognostic value of admission D-dimer level in patients with cardiogenic shock after acute myocardial infarction. [Journal Article]Front Cardiovasc Med. 2022; 9:1083881.FC
- CONCLUSIONS: Admission D-dimer level was independently associated with the short-term outcome in patients with CS complicating AMI and addition of D-dimer brought incremental risk prediction value to traditional risk prediction scores.
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- Recurring episodes of bundle branch reentry ventricular tachycardia due to aortitis preceded by SARS-CoV-2 infection: a case report. [Case Reports]
- CONCLUSIONS: We present a rare case of aortitis complicated with life-threatening ventricular tachycardia presided by Covid-19 infection without major respiratory symptoms. Given a known normal AV conduction prior to the COVID-19 infection, it seems likely that the ensuing aortitis in turn affected the septal myocardium, enabling the reentry tachycardia. Generally, bundle branch reentry tachycardia is best treated with radiofrequency ablation, but if it is due to aortitis with myocardial affection, long-term anti-inflammatory treatment is mandatory to prevent relapse and assure arrhythmia control. Our case highlights importance to recognize the existence of the multisystem inflammatory syndrome in adults (MIS-A) following COVID-19 infection in patients with alarming cardiovascular symptoms. The case shows that the early use of an CT-scan was crucial for both proper diagnosis and treatment option.
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- Bradyarrhythmia In A Marathonist: Cardiac Vagal Denervation As Alternative Treatment. [Journal Article]Rev Port Cardiol. 2023 Jan 21 [Online ahead of print]RP
- Although not routinely used, cardioneuroablation or modulation of the cardiac autonomic nervous system has been proposed as an alternative approach to treat young individuals with enhanced vagal tone and significant atrioventricular (AV) disturbances.We report the case of a 42-year-old athlete with prolonged ventricular pauses associated with sinus bradycardia and paroxysmal episodes of AV block …
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- Safety of Stress Cardiac Magnetic Resonance in Patients With Moderate to Severe Aortic Valve Stenosis. [Journal Article]J Cardiovasc Imaging. 2023 Jan; 31(1):26-38.JC
- CONCLUSIONS: Moderate to severe AS was not associated with complications during CMR stress test. The incidence of non-severe complications and minor symptoms was greater with dobutamine.
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- Evaluation of Arrhythmia Prevalence, Management, and Risk Factors in Patients with Transcatheter and Surgically Closed Secundum Atrial Septal Defects. [Journal Article]Turk Kardiyol Dern Ars. 2023 Jan; 51(1):50-55.TK
- CONCLUSIONS: The higher frequency of arrhythmia in adult studies compared to the pediatric age group once again demonstrates the importance of early diagnosis and treatment of ASD in childhood. The similar incidence of arrhythmia in both groups supports the safety and effectiveness of both closure methods in eligible patients.
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- Conduction Disturbances and Arrhythmia Risk After Septal Reduction Therapy with Alternative Agents: A Pilot Study with EVOH-DMSO and Systematic Review. [Journal Article]Turk Kardiyol Dern Ars. 2023 Jan; 51(1):40-49.TK
- CONCLUSIONS: EVOH-DMSO could cause conduction system problems more common than other non-alcohol agents but less than alcohol septal ablation.
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- Electrocardiographic changes in hospitalised children with COVID-19. [Journal Article]Cardiol Young. 2023 Jan 23 [Online ahead of print]CY
- CONCLUSIONS: The prevalence of arrhythmia in paediatric patients with COVID-19 was detected in 5.5% of the patients. While two-thirds of the electrocardiography abnormalities were sinus bradycardia, ST elevation was remarkable (1.4%). Clinicians should be aware of electrocardiographic abnormalities and consider electrocardiographic monitoring in paediatric patients with COVID-19 and multisystemic inflammatory syndrome in children.
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- The Serious Impact of Comorbidities on Methemoglobinemia: A Case Report. [Case Reports]
- Methemoglobinemia is a rare, life-threatening condition that occurs when the body is exposed to oxidative stress. We present the case of a 72-year-old female with a past medical history of hypertension, obesity, dyslipidemia, and heart failure who was admitted to the emergency department with altered mental status and respiratory failure. After admission, we also identified an atrioventricular bl…
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- Increased whole blood viscosity is associated with primary idiopathic complete atrioventricular block and poor clinical outcomes in these patients. [Journal Article]Clin Hemorheol Microcirc. 2023 Jan 20 [Online ahead of print]CH
- CONCLUSIONS: In this study, WBV was found to be an independent predictor for iCAVB, and in these patients WBV was associated with poor clinical outcomes.
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- Clinical and Echocardiographic Features of Patients with Infective Endocarditis and Bicuspid Aortic Valve According to Echocardiographic Definition of Valve Morphology. [Journal Article]J Am Soc Echocardiogr. 2023 Jan 19 [Online ahead of print]JA
- CONCLUSIONS: Clinical profile and echocardiographic features in BAVIE patients may differ according to valve morphology and patients with BAVIE appear to be referred late, even when BAV disease is previously known.
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- Cardiac arrhythmias and conduction abnormalities in patients with type 2 diabetes. [Journal Article]
- The association between type 2 diabetes (T2D) and the development of cardiac arrhythmias and conduction disturbances has not been extensively studied. Arrhythmia was defined as atrial fibrillation and flutter (AF/AFl), ventricular tachycardia (VT) and ventricular fibrillation (VF), and conduction abnormality as sinus node disease (SND), atrioventricular (AV) block or pacemaker implantation, and i…
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- CineECG illustrating the ventricular activation sequence in progressive AV-junctional conduction block. [Journal Article]J Electrocardiol. 2023 Jan 14; 78:1-4.JE
- We present the use of CineECG in visualizing abnormal ventricular activation in a case of a complex conduction disorder. CineECG combines the standard 12‑lead surface ECG with a 3D anatomical model of the heart. It projects the location and direction of the average ventricular activation and recovery on the heart model over time. In this case, CineECG was able to visualize the different type of f…
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- Prediction of conduction disturbances in patients undergoing transcatheter aortic valve replacement. [Journal Article]Clin Res Cardiol. 2023 Jan 21 [Online ahead of print]CR
- CONCLUSIONS: New-onset left BBB and diabetes mellitus independently predicted HAVB requiring PPM after TAVR and helped to identify patients at risk. Electrophysiologic study (EPS) of atrioventricular conduction was neither specific nor predictive of HAVB and can be skipped.
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- Leadless Pacemaker Implantation in the Emergency Bradyarrhythmia Setting: Results from a Multicenter European Registry. [Multicenter Study]
- Background. Data on leadless pacemaker (LPM) implantation in an emergency setting are currently lacking. Objective. We aimed to investigate the feasibility of LPM implantation for emergency bradyarrhythmia, in patients referred for urgent PM implantation, in a large, multicenter, real-world cohort of LPM recipients. Methods. Two cohorts of LPM patients, stratified according to the LPM implantatio…
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- Ablation of ectopic atrial foci for successful management of symptomatic bradycardia: A case series (Bradycardia and Ectopic Atrial Beats). [Case Reports]Pacing Clin Electrophysiol. 2023 Jan 20 [Online ahead of print]PC
- Atrial premature contractions (PACs) that block at the atrial ventricular (AV) nodal level and occurring in a bigeminal frequency are recognized as a cause of symptomatic bradycardia. Appropriate suppression of the PACs often results in restoration of a regular rhythm with resolution of bradycardia-related symptoms. We report a series of three patients with non-conducted bigeminal PACs arising fr…
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- Lifestyle habits associated with cardiac conduction disease. [Journal Article]Eur Heart J. 2023 Jan 20 [Online ahead of print]EH
- CONCLUSIONS: While some difficult to control comorbidities were associated with conduction disease as expected, a readily modifiable lifestyle factor, physical activity, was associated with a lower risk.
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- An Unexpected Cause of Severe Hypertension and Bradycardia: The Role of Hemodynamic Assessment by Echocardiography. [Case Reports]
- Severe hypertension has numerous etiologies. When accompanied by bradycardia, the spectrum of differential diagnoses is greatly narrowed and is commonly seen in patients with increased intracranial pressure. However, other etiologies such as bradycardia-induced hypertension are rarely mentioned. Here we report the case of a 73-year-old woman presenting with symptoms of heart failure, severe hyper…
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- [Clinical characteristics of Danon disease]. [Journal Article]Zhonghua Xin Xue Guan Bing Za Zhi. 2023 Jan 24; 51(1):51-57.ZX
- Objective: To review the clinical data of 7 patients with Danon disease and analyze their clinical characteristics. Methods: The medical records of 7 patients with Danon disease, who were hospitalized in Peking Union Medical College Hospital of Chinese Academy of Medical Sciences from April 2008 to July 2021, were reviewed and summarized, of which 6 cases were diagnosed as Danon disease by lysoso…
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- [FIP1L1::PDGFRA-positive chronic eosinophilic leukemia showing slowly progressive cardiac impairment]. [Case Reports]Rinsho Ketsueki. 2022; 63(12):1648-1652.RK
- This report describes a 69-year-old man with eosinophilia that was detected during a medical check-up. A review of his medical history revealed that his absolute eosinophil count was 990/µl at the age of 55 and increased to 5,380/µl at the age of 69. Electrocardiogram revealed first-degree atrioventricular block at the age of 58, followed by ST-segment depression and a negative T wave at the age …
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- [Surgical treatment for hypertrophic obstructive cardiomyopathy: a five-year single-center experience of 421 cases]. [Journal Article]Zhonghua Wai Ke Za Zhi. 2023 Jan 18; 61(3):201-208.ZW
- Objectives: To examine the short-term and mid-term effects of surgical treatment of obstructive hypertrophic cardiomyopathy (HCM) in one center. Methods: The perioperative data and short-term follow-up outcomes of 421 patients with obstructive HCM who received surgical treatment at Department of Cardiac Surgery, Zhongshan Hospital, Fudan University from January 2017 to December 2021 were analyzed…
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