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2,695 results
  • Sudden anisocoria in a healing pediatric multitrauma patient. [Journal Article]
    JAAPA. 2023 Feb 01; 36(2):1-3.Harper DS, Bayless S
  • This article describes a teenager who developed anisocoria with no obvious neurologic deficits or decline after a motor vehicle accident. The condition resolved over several hours before reappearing in the opposite eye 2 days later. Again no clinical neurologic deficits were noted and the condition resolved after several hours. The patient's asymptomatic anisocoria was finally determined to be se…
  • StatPearls: Ipratropium [BOOK]
    StatPearls. StatPearls Publishing: Treasure Island (FL)SaabHussienHAboeedAyhamAKern Medical / UCLABOOK
  • Ipratropium maintenance therapy has well-established benefits for the treatment of chronic obstructive lung disease. Mortality in chronic obstructive lung disease is often due to complications, including hyperinflation, decreased exercise tolerance, pulmonary infections, and chronic obstructive lung disease exacerbations. Ipratropium has been extensively studied in clinical trials and proven to p…
  • Torasemide-induced Vascular Purpura in the Course of Eosinophilic Granulomatosis with Polyangiitis. [Case Reports]
    Acta Dermatovenerol Croat. 2022 Sep; 30(2):116-118.Frątczak A, Polak K, … Bergler-Czop B
  • Torasemide is a loop diuretic with a molecule that is chemically similar to the sulphonamides described as eosinophilic granulomatosis with polyangiitis (EGPA) triggering drugs. The presented case is probably the first description of torasemide-induced vascular purpura in the course of EGPA. Any diagnosis of vasculitis should be followed by an identification of drugs that may aggravate the diseas…
  • A case report of an 18-year-old receiving nebulized lidocaine for treatment of COVID-19 cough. [Case Reports]
    Heart Lung. 2023 Jan-Feb; 57:140-143.Welter KJ, Gordon S, … Martin B
  • An 18-year-old girl presenting with respiratory and gastrointestinal symptoms was found to have COVID-19 pneumonia and severe acute respiratory distress syndrome (ARDS). She was transferred to our pediatric intensive care unit (PICU) for ongoing mechanical ventilation and initiation of venovenous extracorporeal membrane oxygenation (VV-ECMO) for management of progressive hypoxic respiratory failu…
  • The Importance of Flexible Bronchoscopy in Difficult-to-treat Asthma from a Pediatric Pulmonology Perspective. [Journal Article]
    Turk Arch Pediatr. 2022 May; 57(3):310-315.Nayir Büyükşahin H, Emiralioğlu N, … Kiper N
  • CONCLUSIONS: To date, there is no prospective study evaluating the importance of flexible fiberoptic bronchoscopy in difficult-to-treat asthma in childhood. In our small cohort, persistent bacterial bronchitis, airway tracheomalacia and/or bronchomalacia, gastroesophageal reflux, and other anatomic anomalies were successfully diagnosed using flexible fiberoptic bronchoscopy and treated without any complications, suggesting that flexible fiberoptic bronchoscopy is an important diagnostic tool with a low complication rate in children with difficult-to-treat asthma.
  • Short-acting inhaled bronchodilators for cystic fibrosis. [Review]
    Cochrane Database Syst Rev. 2022 06 24; 6:CD013666.Smith S, Rowbotham NJ, Edwards CT
  • CONCLUSIONS: All included trials in this review are small and of a cross-over design. Most trials looked at very short-term effects of inhaled bronchodilators, and therefore did not measure longer-term outcomes. The certainty of evidence across all outcomes was very low, and therefore we have been unable to describe any effects with certainty.
  • Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease. [Review]
    Cochrane Database Syst Rev. 2022 05 26; 5:CD013506.Ni H, Aye SZ, Naing C
  • Chronic obstructive pulmonary disease (COPD) is a chronic and progressive disease, often punctuated by recurrent flare-ups or exacerbations. Magnesium sulfate, having a bronchodilatory effect, may have a potential role as an adjunct treatment in COPD exacerbations. However, comprehensive evidence of its effects is required to facilitate clinical decision-making.
  • Combined Pulmonary Fibrosis and Emphysema and Digital Clubbing. [Case Reports]
    Cureus. 2022 Apr; 14(4):e24231.Rasul TF, Bergholz DR, … Fonts E
  • Combined pulmonary fibrosis and emphysema (CPFE) is an underrecognized syndrome that involves simultaneous restrictive-obstructive lung disease. The prognosis is poor, and it frequently occurs with comorbidities. Heavy or former smoking is a major risk factor, and computed tomography (CT) typically shows lower zone fibrosis and upper zone emphysema. Chronic respiratory failure, pulmonary hyperten…
  • TGIF1 overexpression promotes glioma progression and worsens patient prognosis. [Journal Article]
    Cancer Med. 2022 12; 11(24):5113-5128.Wang B, Ma Q, … Li G
  • Transforming growth factor β-induced factor homeobox 1 (TGIF1) reportedly promotes the pathological processes of various malignant tumors. However, few studies have investigated the role of TGIF1 in gliomas. We aimed to explore the relationship between TGIF1 expression and the clinical characteristics of patients with glioma, including their overall survival. A total of thousands transcriptome da…
  • Mass spectrometry detection of inhaled drug in distal fibrotic lung. [Journal Article]
    Respir Res. 2022 May 11; 23(1):118.Mikolasch TA, Oballa E, … Porter JC
  • CONCLUSIONS: In this proof of concept study, using mass spectrometry, we demonstrate for the first-time that an inhaled drug can deposit in distal fibrotic lung parenchyma in patients with Interstitial Lung Disease. This suggests that drugs to treat pulmonary fibrosis could potentially be administered by the inhaled route. Trial registration A prospective clinical study approved by London Camden and Kings Cross Research Ethics Committee and registered on clinicaltrials.gov (NCT03136120).
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