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(Atypical squamous cells of undetermined significance Papanicolaou classification of)
97 results
  • [Precancerous lesions of the cervix and their treatment]. [Journal Article]
    Magy Onkol. 2022 Dec 31; 66(4):280-287.Sobel G
  • Global cervical cancer incidence and mortality rank fourth in women with malignant tumors, which have been reduced by population-based cervical cancer screening. The previously used Papanicolaou cytological testing of cervical smears was replaced by the Bethesda classification, which facilitated the early detection of the pre-cancerous lesions, used together with other methods such as colposcopy,…
  • Comparison of Aptima and hybrid capture-2 HPV tests and Pap test in the referral population in Japan. [Journal Article]
    J Med Virol. 2021 08; 93(8):5076-5083.Kuroki H, Sakamoto J, … Sasagawa T
  • The Aptima human papillomavirus (HPV) test (APTIMA) detects E6-E7 mRNA in abnormal cells in the uterine cervix. To investigate the accuracy of APTIMA for cervical cancer screening in Japan, 423 subjects, mostly referrals with abnormal cytology or being followed up for cervical intraepithelial neoplasia (CIN)1, were screened using two HPV tests, hybrid capture 2 (HC2) and APTIMA, and by the Pap te…
  • Prevalence of Anal Dysplasia in Patients With Inflammatory Bowel Disease. [Journal Article]
    Clin Gastroenterol Hepatol. 2015 Nov; 13(11):1955-61.e1.Shah SB, Pickham D, … Welton M
  • CONCLUSIONS: Although there was a trend toward abnormal anal Papanicolaou tests in IBD subjects compared with HC, there was no difference based on immunosuppression. The presence of HPV did not correlate with abnormal anal cytology. Risk factors associated with this increased trend include female CD subjects and those with a longer duration of CD. ClinicalTrials.gov number: NCT01860963; https://clinicaltrials.gov/ct2/show/NCT01860963.
  • Evaluation of the clinical significance of human papillomavirus (HPV) 53. [Multicenter Study]
    Eur J Obstet Gynecol Reprod Biol. 2015 Aug; 191:7-9.Padalko E, Ali-Risasi C, … Praet M
  • CONCLUSIONS: Our findings support very low to lacking carcinogenic potential of HPV53. Recognising extreme rarity in cervical cancer next to high prevalence in general population of HPV53, further studies investigating progression to high-grade lesions are needed to elucidate the oncogenic potential of pHR-HPV53.
  • Reprocessing unsatisfactory ThinPrep papanicolaou tests using a modified SurePath preparation technique. [Journal Article]
    Cancer Cytopathol. 2014 May; 122(5):343-8.Randolph ML, Wu HH, Crabtree WN
  • CONCLUSIONS: The modified SurePath processing technique was adept at handling nearly all of the challenges that biological and environmental conditions (blood, protein, lubricant, etc) present in liquid-based filter preparations. A total of 1093 (56%) of 1937 unsatisfactory ThinPrep Papanicolaou tests were converted to a satisfactory state, resulting in 116 abnormalities (10.6%) being diagnosed that otherwise would have gone undetected
  • Screening and risk factors for anal cancer precursors in men infected with HIV in Taiwan. [Journal Article]
    J Med Virol. 2014 Feb; 86(2):193-201.Cheng SH, Chu FY, … Hsueh YM
  • Homosexual men infected with human immunodeficiency virus (HIV) are at a greater risk of developing anal cancer. Men who are infected with HIV and visited the outpatient clinics in Taoyuan General Hospital were enrolled to this study. During March to December 2011, thin preparation anal Pap smear and human papillomavirus (HPV) genotyping were performed in 230 subjects, of which 69 subjects underw…
  • Improved abnormal Pap smear triage using cervical cancer biomarkers. [Journal Article]
    J Low Genit Tract Dis. 2014 Jan; 18(1):1-7.Killeen JL, Dye T, … Hiraoka M
  • CONCLUSIONS: The triage of abnormal Pap smears by p16/Ki-67 immunostaining shows comparable sensitivity, improved specificity, and significantly improved diagnostic performance when compared to hr-HPV. Immunostaining is of value in triaging LSIL and ASC-H Pap smears in addition to ASCUS. The widespread utilization of biomarker triage could result in significant health care cost savings without compromising the detection of significant cervical cancer precursors.
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