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68,980 results
  • Catatonia in neurodevelopmental disorders: assessing catatonic deterioration from baseline. [Review]
    Lancet Psychiatry. 2023 Jan 25 [Online ahead of print]Hauptman AJ, Cohen D, … Ferrafiat V
  • Despite the inclusion of catatonia as a specifier of autism spectrum disorder in DSM-5, we-a team of child and adolescent neuropsychiatrists who specialise in paediatric catatonia and neurodevelopmental disorders-have identified a number of issues with the diagnosis and clinical management of catatonia in our patients. In this Personal View, we summarise the literature regarding catatonia in peop…
  • Autism spectrum disorder and personality disorders: How do clinicians carry out a differential diagnosis? [Journal Article]
    Autism. 2023 Jan 28 [Online ahead of print]Allely CS, Woodhouse E, Mukherjee RA
  • It is now recognised that autism spectrum disorder (ASD) and personality disorders (PDs) have a variety of factors in common. However, the exact nature of the relationship between ASD and the PDs remains unclear. The overlapping symptom profiles of ASD and PDs can lead to diagnostic uncertainty - features of ASD and PD can be misattributed and easily lead to misdiagnosis of ASD patients. Since di…
  • A Mixed Methods Study of Autistic Adults' Mental Health Therapy Experiences. [Journal Article]
    Clin Psychol Psychother. 2023 Jan 27 [Online ahead of print]Mazurek MO, Pappagianopoulos J, … Harkins C
  • Autistic adults are at high risk for co-occurring mental health problems and need access to effective and appropriate mental health treatment. However, the relative effectiveness or acceptability of specific mental health strategies among autistic adults has not been previously examined. The current study sought to gain a deeper understanding of autistic adults' experiences and preferences regard…
  • Influence of parental knowledge and attitudes on the oral and dental health status of autistic children: A systematic review. [Journal Article]
    Spec Care Dentist. 2023 Jan 27 [Online ahead of print]Salmeh A, Al-Saadi M, … Al-Rawi N
  • CONCLUSIONS: Autistic children are susceptible to oral diseases, necessitating parental attention. Current evidence regarding this topic is limited and conflicting. The present systematic review faces limitations: included studies were few and predominantly cross-sectional. Moreover, study samples were small, predominantly male, conveniently recruited, and geographically limited. This paper serves as a foundation to guide future research and inspire oral health education and wellness promotion programs.
  • Gene×environment interactions in autism spectrum disorders. [Journal Article]
    Curr Top Dev Biol. 2023; 152:221-284.Keil-Stietz K, Lein PJ
  • There is credible evidence that environmental factors influence individual risk and/or severity of autism spectrum disorders (hereafter referred to as autism). While it is likely that environmental chemicals contribute to the etiology of autism via multiple mechanisms, identifying specific environmental factors that confer risk for autism and understanding how they contribute to the etiology of a…
  • Visual processing of complex social scenes in 22q11.2 deletion syndrome: Relevance for negative symptoms. [Journal Article]
    Psychiatry Res. 2023 Jan 24; 321:115074.Dubourg L, Kojovic N, … Schneider M
  • Current explanatory models of negative symptoms in schizophrenia have suggested the role of social cognition in symptom formation and maintenance. This study examined a core aspect of social cognition, namely social perception, and its association with clinical manifestations in 22q11.2 deletion syndrome (22q11DS), a genetic model of schizophrenia. We used an eye-tracking device to analyze develo…
  • Evaluation of Chronic Constipation in Children With Autism Spectrum Disorder. [Journal Article]
    J Pediatr Gastroenterol Nutr. 2023 Feb 01; 76(2):154-159.Coe A, Ciricillo J, … Williams KC
  • CONCLUSIONS: Chronic constipation does not appear to be associated with a higher rate of abnormal colonic motility in children with ASD. Clinical information of disease duration and presence of soiling due to constipation show promise in identifying patients with ASD at a greater risk for abnormal colonic motility.
  • Factors predicting current and future use of video-modelling in teaching students with autism spectrum disorder (ASD): a Saudi Arabian perspective. [Journal Article]
    Disabil Rehabil Assist Technol. 2023 Jan 26 [Online ahead of print]Aldabas R, Alhossein A
  • CONCLUSIONS: Results show that video-modelling is still used as an assistive technology slightly in teaching students with ASD, suggesting that educators may find it challenging to use video-modelling in classrooms. Results indicate that using video-modelling in teaching students with ASD can be influenced by a variety of factors related to the Diffusion of Innovation Theory. This is evidence that educational and rehabilitation stakeholders need to cooperate in addressing these factors to close the research-practice gap, and improve the adoption of video-modelling in classrooms.IMPLICATIONS FOR REHABILITATIONFew studies have addressed how video-modelling as an assistive technology is being adopted in the classroom.The findings revealed that video-modelling was underutilized in the classrooms for students with ASD, indicating the need to investigate causes contributing to this lack of adoption and to increase video-modelling use.Perceived relative advantage, complexity, trialability, and observability predicted educators' current video-modelling use.Perceived relative advantage and trialability predicted educators' future video-modelling use.Support should be done via collaboration among special educators and other professionals (e.g., assistive technology specialists, occupational and physical therapists) to help in development of and use video-modelling more extensively.
  • Adaptive noise depression for functional brain network estimation. [Journal Article]
    Front Psychiatry. 2022; 13:1100266.Ma D, Peng L, Gao X
  • Autism spectrum disorder (ASD) is one common psychiatric illness that manifests in neurological and developmental disorders, which can last throughout a person's life and cause challenges in social interaction, communication, and behavior. Since the standard ASD diagnosis is highly based on the symptoms of the disease, it is difficult to make an early diagnosis to take the best cure opportunity. …
  • Development and validation of the Executive Functioning Scale. [Journal Article]
    Front Psychiatry. 2022; 13:1078211.Uljarević M, Cai RY, … Frazier TW
  • Executive functioning (EF) processes are essential for adaptive and flexible responding to the demands and complexities of everyday life. Conversely, if impaired, these processes are a key transdiagnostic risk factor that cuts across autism and a range of other neurodevelopmental (NDD) and neuropsychiatric (NPD) conditions. However, there are currently no freely available informant-report measure…
  • GRIN2B-related neurodevelopmental disorder: current understanding of pathophysiological mechanisms. [Review]
    Front Synaptic Neurosci. 2022; 14:1090865.Sabo SL, Lahr JM, … Sceniak MP
  • The GRIN2B-related neurodevelopmental disorder is a rare disease caused by mutations in the GRIN2B gene, which encodes the GluN2B subunit of NMDA receptors. Most individuals with GRIN2B-related neurodevelopmental disorder present with intellectual disability and developmental delay. Motor impairments, autism spectrum disorder, and epilepsy are also common. A large number of pathogenic de novo mut…
  • A Hypothalamic Perspective of Human Socioemotional Behavior. [Journal Article]
    Neuroscientist. 2023 Jan 26 [Online ahead of print]Caria A
  • Historical evidence from stimulation and lesion studies in animals and humans demonstrated a close association between the hypothalamus and typical and atypical socioemotional behavior. A central hypothalamic contribution to regulation of socioemotional responses was also provided indirectly by studies on oxytocin and arginine vasopressin. However, a limited number of studies have so far directly…
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