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(Autoimmune hemolytic anemia)
7,506 results
  • Acute Kidney Injury Caused by Evans Syndrome with Systemic Lupus Erythematosus and Systemic Sclerosis. [Journal Article]
    Intern Med. 2020 Oct 28 [Online ahead of print]Matsuoka N, Watanabe H, … Wada J
  • A 65-year-old woman with systemic sclerosis and systemic lupus erythematosus developed acute kidney injury (AKI), Coombs-positive autoimmune hemolytic anemia and autoimmune thrombocytopenia; therefore, she was diagnosed with Evans syndrome (ES). Intravascular hemolysis was suggested as the cause of AKI based on the presence of acute tubular injury and trace hemosiderin deposits on the renal biops…
  • A case of megaloblastic anemia simulating a cold autoimmune hemolytic anemia. [Journal Article]
    Immunohematology. 2020 Sep; 36(3):89-92.De La Puerta R, Carpio N, … Solves P
  • CONCLUSIONS: We report a case of pernicious anemia in which the first diagnosis suspicion was cold autoimmune hemolytic anemia (cAIHA) due to the presence of cold autoantibodies. A 47-year-old woman with a medical history of autoimmune thyroid disease came to the hospital with a clinical and serologic presentation of AIHA. However, because of determination of vitamin B12 (VB12) deficiency, she was finally diagnosed with megaloblastic anemia. In the acute period, the patient received short-term corticosteroid therapy and later VB12. The patient's hemoglobin level and general condition showed improvement.
  • Complement in secondary thrombotic microangiopathy. [Review]
    Kidney Int Rep. 2020 Oct 21 [Online ahead of print]Palma LMP, Sridharan M, Sethi S
  • Thrombotic microangiopathy (TMA) is a condition characterized by thrombocytopenia and microangiopathic hemolytic anemia (MAHA) with varying degrees of organ damage in the setting of normal International Normalized Ratio (INR) and activated Partial Thromboplastin Time (aPTT). Complement has been implicated in the etiology of TMA, which are classified as Primary TMA - when genetic and acquired defe…
  • Acute and fatal cephalosporin-induced autoimmune hemolytic anemia. [Journal Article]
    Br J Clin Pharmacol. 2020 Oct 19 [Online ahead of print]Boilève A, Gavaud A, … Jozwiak M
  • We report the case of an 82-year old male patient admitted in our medical intensive care unit for diffuse skin lesions, three days after the onset of ceftriaxone for bilateral pneumonia without microbiological documentation. The patient concomitantly exhibited diffuse skin lesions compatible with livedo and neurological and hemodynamic failure. Biological analysis revealed acute hemolytic anemia.…
  • The impact of autoimmune cytopenias on the clinical course and survival of Hodgkin lymphoma. [Journal Article]
    Int J Hematol. 2020 Oct 15 [Online ahead of print]Pinczés LI, Szabó R, … Illés Á
  • The characteristics of autoimmune cytopenias (AICP) associated with Hodgkin lymphoma (HL) are not thoroughly defined. We retrospectively assessed the clinical features of HL-associated AICPs in 563 HL patients diagnosed over a period of 28 years. We identified 8 cases of autoimmune hemolytic anemia (AIHA) and 8 cases of autoimmune thrombocytopenia among 14 patients altogether. Four (26%) AICPs we…
  • A Rare Case of Hemoglobin E/Beta-Thalassemia and Systemic Lupus Erythematosus. [Case Reports]
    Cureus. 2020 Sep 09; 12(9):e10332.Khamees I, Mohammad Obeidat I, … Yassin MA
  • Systemic lupus erythematosus (SLE) is a systemic autoimmune disease, with multisystemic involvement. Hemoglobin E/beta-thalassemia (HbE/beta-thalassemia) is the genotype responsible for approximately one-half of all severe beta-thalassemia worldwide. When beta-thalassemia and SLE coexist, SLE seems to have a more severe course. Here we report a 32-year-old female who presented with dizziness and …
  • Alectinib-induced Immune Hemolytic Anemia in a Patient with Lung Adenocarcinoma. [Journal Article]
    Intern Med. 2020 Sep 30 [Online ahead of print]Okumoto J, Sakamoto S, … Hattori N
  • Drug-induced immune hemolytic anemia (DIIHA) is a rare condition with an increasing incidence associated with the frequent use of certain drugs. An 85-year-old woman with lung adenocarcinoma prescribed alectinib complained of dyspnea on exertion at our hospital. Based on her laboratory tests results on admission, we focused on the clinical course of anemia and hemolysis progression after alectini…
  • Autoimmunity Following Allogeneic Hematopoietic Stem Cell Transplantation. [Review]
    Front Immunol. 2020; 11:2017.Buxbaum NP, Pavletic SZ
  • Autoimmune manifestations after allogeneic hematopoietic stem cell transplantation (AHSCT) are rare and poorly understood due to the complex interplay between the reconstituting immune system and transplant-associated factors. While autoimmune manifestations following AHSCT have been observed in children with graft-versus-host disease (GvHD), an alloimmune process, they are distinct from the latt…
  • [Autoimmune hemolytic anemia: Case review]. [Journal Article]
    An Pediatr (Barc). 2020 Sep 21 [Online ahead of print]Sánchez N, Zubicaray J, … Sevilla J
  • CONCLUSIONS: Our case series confirms that AIHA is a very rare disease in childhood. Most cases evolve favorably, although up to a quarter of them require second lines of treatment and, in exceptional cases, they need very aggressive treatments. These latter cases generally correspond to patients who present more than one cytopenia in the course of the disease.
  • Lung diseases and autoimmune hemolytic anemia associted with IgG4 disease. [Journal Article]
    Vnitr Lek. 2020 Summer; 66(4):47-52.Doubková M, Matěj R, … Doubek M
  • IgG4 related disease (IgG4-RD) is a rare and relatively new group of systemic inflammatory diseases characterized by inflammatory, fibrotic or sclerotic involvement of one or more organs accompanied by increased IgG4plasma cells tissue infiltration andusually elevated serum IgG4(IgG4 > 1.35g/l, normal range 0.08-1.40 g/l) level. Histopathological findings are crucial for the diagnostics of this d…
  • Atypical Hemolytic Uremic Syndrome: New Challenges in the Complement Blockage Era. [Review]
    Nephron. 2020 Sep 18 [Online ahead of print]Avila Bernabeu AI, Cavero Escribano T, Cao Vilarino M
  • Atypical hemolytic uremic syndrome (aHUS) is a rare cause of thrombotic microangiopathy (TMA), characterized by microangiopathic hemolytic anemia, consumptive thrombocytopenia, and multisystem end organ involvement, most commonly affecting the kidney. Diagnosis is clinical, after exclusion of other TMA causes. Primary aHUS arises from genetic abnormalities, resulting in uncontrolled complement ac…
  • Prognostic significance of hemoglobin level and autoimmune hemolytic anemia in SARS-CoV-2 infection. [Journal Article]
    Ann Hematol. 2020 Sep 12 [Online ahead of print]Algassim AA, Elghazaly AA, … Aljurf MD
  • Higher levels of D-dimer, LDH, and ferritin, all have been associated with the poor prognosis of COVID-19. In a disease where there are acute inflammation and compromised oxygenation, we investigated the impact of initial hemoglobin (Hgb) levels at Emergency Department (ED) triage on the severity and the clinical course of COVID-19. We conducted a cross-sectional study on 601 COVID-19 patients in…
  • Biphasic Squamoid Alveolar Renal Cell Carcinoma of the Kidney Involved by Atypical CD5-Positive B-Cells. [Journal Article]
    Int J Surg Pathol. 2020 Sep 10 [Online ahead of print]Zhang X, Tretiakova M
  • Biphasic squamoid alveolar renal cell carcinoma (BSARCC) is a recently described kidney cancer entity with <60 published cases so far. Some unique features of BSARCC include distinct squamoid and alveolar morphology forming glomeruloid configurations and 2 types of tumor cells with different immunoprofiles. Although the mechanism is unknown, neutrophils and cellular materials engulfed by larger t…
  • Pembrolizumab-Induced Cold Agglutinin Disease. [Journal Article]
    Am J Case Rep. 2020 Sep 05; 21:e924283.Atiq O, Atiq SO, … Atiq OT
  • CONCLUSIONS: Our case shows a unique presentation of CAD, initially presumed to be myelosuppression secondary to chemotherapy. Instead, a peripheral smear revealed Pembrolizumab to be the cause of cold agglutinin disease. Due to the relatively unknown association between these 2 entities, patient care was delayed. Finally, after initiation of Rituximab therapy, the patient's CBC began to recover.
  • IgG4-related diseases with autoimmune hemolytic anemia: A case report. [Case Reports]
    Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2020 Jun 28; 45(6):739-744.Pend M, Yang L, Wu S
  • IgG4-related disease (IgG4-RD) is a rare autoimmune fibrosis disease characterized by elevated serum IgG4 and tissues as well as organs infiltrated with IgG4-positive cells, resulting in swelling and damage.It is currently treated as first-line treatment with glucocorticoids. Autoimmune hemolytic anemia (AIHA) is also a relatively rare disease that caused by autoreactive erythrocyte antibodies. A…
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