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(Autoimmune thrombocytopenic purpura)
11,757 results
  • Hereditary thrombotic thrombocytopenic purpura acquired through liver transplantation: a case report. [Case Reports]
    Am J Transplant. 2022 Dec 30 [Online ahead of print]Martin KA, Zakarija A, … Stein R
  • A 62-year-old received orthotopic liver transplantation. Three weeks later, thrombotic microangiopathy developed. Testing revealed thrombotic thrombocytopenic purpura (TTP) characterized by low ADAMTS13 (A Disintegrin-like Metallopeptidase with ThromboSpondin type 1 motif 13) activity and no inhibitor of ADAMTS13 protein. Retrospective attainment of donor records revealed a TTP diagnosis, presuma…
  • Pseudo-thrombotic microangiopathy due to folate deficiency. [Case Reports]
    BMJ Case Rep. 2023 Jan 20; 16(1)Larkin E, Konkol S, Geraghty M
  • Classically, deficiencies of vitamin B12 and folate are associated with megaloblastic anaemia. Additionally, vitamin B12 is able to cause a haemolytic anaemia in the form of pseudo-thrombotic microangiopathy (pseudo-TMA). Here, we present a case of a middle-aged woman with a history of Roux-en-Y gastric bypass who presented with dyspnoea and fatigue and was found to have thrombocytopenia and a no…
  • Management of Helicobacter pylori infection. [Review]
    JGH Open. 2023 Jan; 7(1):3-15.Aumpan N, Mahachai V, Vilaichone RK
  • Helicobacter pylori infection exhibits a wide disease spectrum ranging from asymptomatic gastritis, peptic ulcer disease, to gastric cancer. H. pylori can induce dysbiosis of gastric microbiota in the pathway of carcinogenesis and successful eradication can restore gastric homeostasis. Diagnostic testing and treatment for H. pylori infection is recommended in patients with active or past history …
  • How we treat primary immune thrombocytopenia in adults. [Review]
    J Hematol Oncol. 2023 Jan 19; 16(1):4.Liu XG, Hou Y, Hou M
  • Primary immune thrombocytopenia (ITP) is an immune-mediated bleeding disorder characterized by decreased platelet counts and an increased risk of bleeding. Multiple humoral and cellular immune abnormalities result in accelerated platelet destruction and suppressed platelet production in ITP. The diagnosis remains a clinical exclusion of other causes of thrombocytopenia. Treatment is not required …
  • Thrombotic thrombocytopenic purpura with neurological impairment: A Review. [Case Reports]
    Medicine (Baltimore). 2022 Dec 09; 101(49):e31851.Zhu H, Liu JY
  • The last 2 decades have witnessed considerable advances in our understanding of thrombotic thrombocytopenic purpura (TTP). However, there is still some ambiguity regarding the precise nature of this disease, especially with respect to nervous system involvement and the correct nomenclature. This article seeks to summarize the clinical manifestations of TTP and the associated diseases. We describe…
  • Advances in management of pediatric chronic immune thrombocytopenia: a narrative review. [Journal Article]
    J Yeungnam Med Sci. 2023 Jan 09 [Online ahead of print]Lee JM
  • Immune thrombocytopenia (ITP) is a disease in which thrombocytopenia occurs because of immune-mediated platelet destruction and decreased platelet production. Although many pediatric patients with ITP experience spontaneous remission or reach remission within 12 months of first-line therapy, approximately 20% progress to chronic ITP. Patients who do not respond to first-line treatment or experien…
  • Prolonged Thrombocytopenia in a Case of MIS-C in a Vaccinated Child. [Case Reports]
    J Investig Med High Impact Case Rep. 2023 Jan-Dec; 11:23247096221145104.Demharter NS, Rao P, … Clarke S
  • Multisystem inflammatory syndrome in children (MIS-C) has been extensively described in patients following severe acute respiratory syndrome coronavirus 2 infection. There are now questions about what MIS-C may look like in vaccinated children. Multisystem inflammatory syndrome in children has many clinical and laboratory features in common with other inflammatory disorders including Kawasaki dis…
  • Pediatric refractory immune thrombocytopenia: A systematic review. [Review]
    Pediatr Blood Cancer. 2023 Mar; 70(3):e30173.Ibrahim L, Dong SX, … Lambert M
  • Pediatric immune thrombocytopenia (ITP) is an acquired disorder associated with autoimmune destruction and impairment of platelet production in children. Some children exhibit poor or transient response to ITP-directed treatments and are referred to as having refractory ITP (rITP). There is currently no consensus on the definition of rITP, nor evidence-based treatment guidelines for patients with…
  • Immune thrombocytopenic purpura secondary to COVID-19 vaccination: A systematic review. [Review]
    Eur J Haematol. 2022 Dec 23 [Online ahead of print]Bidari A, Asgarian S, … Naderkhani M
  • CONCLUSIONS: De novo ITP is a rare complication of COVID-19 vaccination, and corresponding reports belong to mRNA-based and adenovirus vector-based vaccines, in order of frequency. This frequency pattern may be related to the scale of administration of individual vaccines and their potency in inducing autoimmunity. The more the COVID-19 vaccine is potent to induce antigenic challenge, the shorter the lag time would be. Most patients had a benign course and responded to typical treatments of primary ITP.
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