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Unbound Medicine.
(Autonomic dysfunction)
48,440 results
  • Autonomic dysfunction and postural orthostatic tachycardia syndrome in post-acute COVID-19 syndrome. [Journal Article]
    Nat Rev Cardiol. 2023 Feb 02 [Online ahead of print]Fedorowski A, Sutton R
  • The post-acute sequelae of COVID-19 present major problems for many patients, their physicians and the health-care system. They are unrelated to the severity of the initial infection, are often highly symptomatic and can occur after vaccination. Many sequelae involve cardiovascular autonomic dysfunction, with postural orthostatic tachycardia syndrome in 30% of individuals. Prognosis is unknown, a…
  • Vagal cross-sectional area correlates with parasympathetic dysfunction in Parkinson's disease. [Journal Article]
    Brain Commun. 2023; 5(1):fcad006.Huckemann S, Mueller K, … Pitarokoili K
  • The aim of this prospective study was to investigate autonomic function in Parkinson's disease with a multidimensional approach including clinical evaluation tools, head-up tilt test and morphological studies of the vagus nerve. Head-up tilt test parameters including high frequency power of the heart frequency interval, the ratio of low frequency power of the distance between two consecutive R wa…
  • Phenotypes of Overdiagnosed Long QT Syndrome. [Journal Article]
    J Am Coll Cardiol. 2023 Feb 07; 81(5):477-486.Bains S, Neves R, … Ackerman MJ
  • CONCLUSIONS: Knowing the 5 main determinants of discordance between a previously rendered diagnosis of LQTS and full diagnostic reversal or removal (vasovagal syncope, "pseudo"-positive genetic test result in LQTS-causative genes, family history of SCD, transient QT prolongation, and misinterpretation of the QTc interval) increases awareness and provides critical guidance to reduce this burden of overdiagnosed LQTS.
  • Management of harlequin syndrome under ECPELLA support: A report of two cases and a proposed approach. [Case Reports]
    Ann Card Anaesth. 2023 Jan-Mar; 26(1):97-101.Giunta M, Recchia EG, … Brazzi L
  • The use of ECPELLA in patients with severe lung disease may result in an unfavorable phenomenon of differential hypoxia. The simultaneous evaluation of three arterial blood samples from different arterial line (right radial artery, left radial artery, ECMO arterial line) in patients at risk of Harlequin syndrome (also called differential hypoxemia (DH)) can localize the "mixing cloud" along the a…
  • [Risk factors associated with malignant vasovagal syncope in children]. [Journal Article]
    Zhonghua Er Ke Za Zhi. 2023 Feb 02; 61(2):131-135.Sun R, Kang YY, … Li XH
  • Objective: To analyze the clinical characteristics and risk factors of malignant vasovagal syncope (VVS) in children. Methods: This was a case-control study. The data of 368 VVS patients who were treated in the Department of Cardiology, Children's Hospital, Capital Institute of Pediatrics from June 2017 to December 2021 was collected and analyzed. They were divided into malignant VVS group and no…
  • [Gut microbiota in patients with relapsing-remitting multiple sclerosis]. [Review]
    Zh Nevrol Psikhiatr Im S S Korsakova. 2023; 123(1):8-15.Tardov MV, Talapbek S, … Suvorova NN
  • Microorganisms in human life play a huge role: in particular, those that coexist with the host organism, inhabiting the skin, upper respiratory tract, external genitalia and especially the digestive tract. The intestinal microbiota, including bacteriome, mycobiome and virome, not only takes part in the digestion process, but also provides the synthesis of a number of vitamins. The intestinal micr…
  • Postural orthostatic tachycardia syndrome: Recognition and treatment. [Journal Article]
    Nursing. 2023 Feb 01; 53(2):18-22.Czosek L
  • Postural orthostatic tachycardia syndrome (POTS) affects 3 million in the US and 11 million globally. Signs and symptoms can vary and greatly impact a patient's quality of life. This article focuses on the prevalence, clinical manifestations, diagnosis, treatment, and patient education surrounding POTS.
  • [Orthostatic hypotension: focus on a common pathology sometimes misknowned]. [Journal Article]
    Geriatr Psychol Neuropsychiatr Vieil. 2022 Dec 01; 20(4):421-428.Michon PL, Kahn JE, … Pepin M
  • Orthostatic hypotension is a frequent pathology especially in older adults and inhospital patients. Prevalence is increasing with age, and is about 30 % of patients older than 65 years. Orthostatic hypotension is defined as a fall in blood pressure of at least 20 mmHg systolic or 10 mmHg diastolic when standing or during head-up tilt testing. Orthostatic hypotension is significantly associated wi…
  • Anti-IgLON5 Disease with Isolated Hemichorea: A Case Report and Review of the Literature. [Review]
    Mov Disord Clin Pract. 2023 Jan; 10(1):115-119.Grossauer A, Hussl A, … Heim B
  • CONCLUSIONS: Our results support the diversity of clinical phenotypes in anti-IgLON5 disease, adding isolated hemichorea to the spectrum of presenting symptoms. As sleep-related disorders are often not the leading reason for consultation and only revealed by PSG examination, we suggest that screening for antibodies against IgLON5 should be considered in patients presenting with unexplained movement disorders, including isolated hemichorea.
  • Lessons of the month: Giant cell arteritis with Horner's syndrome and vertebral dissection. [Case Reports]
    Clin Med (Lond). 2023 Jan; 23(1):94-96.Vaidya K, Gor S, … Waheed A
  • We present a case of an 82-year-old woman presenting with left-sided Horner's syndrome and stroke. She also had a 6-week history of intermittent dizziness, reduced appetite, lethargy, muscle stiffness and weight loss. Examination revealed left temporal artery and left posterior auricular artery tenderness. Her ESR showed 62 mm/hr and imaging showed left vertebral artery dissection. Temporal arter…
  • Human pancreatic capillaries and nerve fibers persist in type 1 diabetes despite beta cell loss. [Journal Article]
    Am J Physiol Endocrinol Metab. 2023 Jan 25 [Online ahead of print]Richardson TM, Saunders DC, … Brissova M
  • The autonomic nervous system regulates pancreatic function. Islet capillaries are essential for the extension of axonal projections into islets, and both of these structures are important for appropriate islet hormone secretion. Because beta cells provide important paracrine cues for islet glucagon secretion and neurovascular development, we postulated that beta cell loss in type 1 diabetes (T1D)…
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