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34,646 results
  • International evidence-based guidelines on hypertension and type 2 diabetes mellitus: A systematic review. [Review]
    J Public Health Res. 2023 Jan; 12(1):22799036221146913.Melichova J, Sivco P, … Majdan M
  • This systematic review provides a high-quality, comprehensive summary of recommendations on hypertension (HT) and type 2 diabetes mellitus (T2DM), accentuating patient blood pressure, HbA1c levels, patterns of drug treatment, management, and screening of these diseases. The overall objective of the review is to support adapting existing clinical practice guidelines in Indonesia, Vietnam, and Myan…
  • Targeting lipid metabolism in metastatic prostate cancer. [Review]
    Ther Adv Med Oncol. 2023; 15:17588359231152839.Scheinberg T, Mak B, … Horvath LG
  • Despite key advances in the treatment of prostate cancer (PCa), a proportion of men have de novo resistance, and all will develop resistance to current therapeutics over time. Aberrant lipid metabolism has long been associated with prostate carcinogenesis and progression, but more recently there has been an explosion of preclinical and clinical data which is informing new clinical trials. This re…
  • Endocrine disorders and fertility and pregnancy: An update. [Review]
    Front Endocrinol (Lausanne). 2022; 13:970439.Bendarska-Czerwińska A, Zmarzły N, … Grabarek BO
  • It is estimated that more and more couples suffer from fertility and pregnancy maintenance disorders. It is associated with impaired androgen secretion, which is influenced by many factors, ranging from genetic to environmental. It is also important to remember that fertility disorders can also result from abnormal anatomy of the reproductive male and female organ (congenital uterine anomalies - …
  • Obesity management: Attitudes and practice of Italian endocrinologists. [Journal Article]
    Front Endocrinol (Lausanne). 2022; 13:1061511.Chianelli M, Busetto L, … Nicolucci A
  • Obesity is a global pandemic and is cause of serious concern in all regions of the world. It is important to raise the attention of health care professionals in order to provide early treatment of patients with obesity. Obesity management, however, varies greatly amongst endocrinologists with respect to attitudes to diagnosis and treatment. Aim of this study was to identify practices and needs of…
  • Effects of Systemic Drugs on the Development and Progression of Age-Related Macular Degeneration. [Review]
    Surv Ophthalmol. 2023 Jan 30 [Online ahead of print]Grimes KR, Aloney A, … Chhablani J
  • Age-related macular degeneration (AMD) is the leading cause of severe loss of central vision among people over 50. The pathophysiology of the disease is multifactorial and can be attributed to genetics, aging, inflammation, environmental factors, and lifestyle factors including smoking, diet, obesity, and alcohol consumption. While there is no treatment for dry AMD, the current standard treatment…
  • Postop Complication With Euglycemic Diabetic Ketoacidosis in a Patient Receiving Empagliflozin. [Case Reports]
    Cureus. 2022 Dec; 14(12):e33161.Fustiga J, Fernandes M, … Rodrigues C
  • Euglycemic diabetic ketoacidosis (EDKA) is an uncommon diabetic complication with increasing prevalence and is associated with the use of sodium-glucose co-transporter 2 inhibitors (SGLT2i). We report the case of a 77-year-old female patient with type 2 diabetes mellitus, treated with metformin/linagliptin and empagliflozin, who initiated a slurred speech and altered level of consciousness in the…
  • AMPK Activation Restores Salivary Function Following Radiation Treatment. [Journal Article]
    J Dent Res. 2023 Feb 01 [Online ahead of print]Meyer RK, Gilman KE, … Limesand KH
  • Head and neck cancers represent a significant portion of cancer diagnoses, with head and neck cancer incidence increasing in some parts of the world. Typical treatment of early-stage head and neck cancers includes either surgery or radiotherapy; however, advanced cases often require surgery followed by radiation and chemotherapy. Salivary gland damage following radiotherapy leads to severe and ch…
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