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Unbound Medicine.
(Avascular necrosis of bone)
24,232 results
  • Joint replacement and human immunodeficiency virus. [Review]
    World J Virol. 2023 Jan 25; 12(1):1-11.Salimi M, Mirghaderi P, … Salimi A
  • The incidence of human immunodeficiency virus (HIV)-infected cases that need total joint replacement (TJR) is generally rising. On the other hand, modern management of HIV-infected cases has enabled them to achieve longevity while increasing the need for arthroplasty procedures due to the augmented dege-nerative joint disease and fragility fractures, and the risk of osteonecrosis. Although initia…
  • Total Talus Replacements. [Review]
    Foot Ankle Orthop. 2023 Jan; 8(1):24730114221151068.Jennison T, Dalgleish J, … Goldberg A
  • CONCLUSIONS: Total talus replacements are a promising alternative to tibiotalocalcaneal fusion for patients with avascular necrosis of the talus; however, further studies are required to ensure reliable outcomes prior to widespread adoption of this technology.
  • Benign osteonecrosis of the external ear canal: case series. [Case Reports]
    J Surg Case Rep. 2023 Jan; 2023(1):rjad016.Chandler K, Hawthorne M, Georgolios A
  • Benign osteonecrosis of the external ear canal is a rare pathology that commonly gets misdiagnosed as cholesteatoma of the external ear canal, keratosis obturans and malignant otitis externa. Each pathology has characteristics that allow for differentiation between them. Careful analysis is required to diagnose properly and determine the best modality of management. This case series presents two …
  • Revision Amputation with Press-Fit Osseointegration for Transfemoral Amputees. [Journal Article]
    JBJS Essent Surg Tech. 2022 Apr-Jun; 12(2)Hoellwarth JS, Reif TJ, Rozbruch SR
  • Press-fit transfemoral osseointegration is the technique of inserting an intramedullary metal implant into the residual femur of an amputee; the implant is passed transcutaneously to attach to a standard prosthesis that includes a knee, tibia, ankle, and foot. This allows the prosthesis to be skeletally anchored, eliminating socket-related problems such as tissue compression that can provoke neur…
  • Surgical Trends for Managing Knee Osteonecrosis: a 2010 to 2020 United States Nationwide Study. [Journal Article]
    J Arthroplasty. 2023 Feb 02 [Online ahead of print]Ng MK, Gordon AM, … Mont MA
  • CONCLUSIONS: To our knowledge, this is the first study to characterize surgical trends in management of knee ON. Overall surgical volume for knee ON has continued to increase, outpacing population growth. Patients who have knee ON are most commonly managed with arthroplasty procedures, specifically TKA. Younger aged patients (<50 years) are more likely to undergo joint-preserving procedures, namely core decompression.
  • The influence of diagnoses on patient satisfaction during inpatient stays: A prospective study. [Journal Article]
    J Craniomaxillofac Surg. 2023 Jan 28 [Online ahead of print]Otto B, Borzikowsky C, … Hertrampf K
  • The aim of this study was to assess patient satisfaction relating to inpatient stays. In this prospective observational study, adult patients with oncological (oral cancer, medication-related osteonecrosis of the jaw) and non-oncological (mandibular fracture) diagnoses, and who had undergone surgery, were contacted 4 weeks after discharge. Two validated questionnaires were used: EORTC QLQ-C30 for…
  • Quantitative analysis of local microcirculation changes in early osteonecrosis of femoral head: DCE-MRI findings. [Journal Article]
    Front Surg. 2022; 9:1003879.Li P, Xie C, … Yu F
  • CONCLUSIONS: ONFH is a complex ischemic lesion caused by changes in local microcirculation. It mainly manifests as increased permeability of the vascular wall, blood stasis in the posterior circulation, high intraosseous pressure in the femoral head, and decreased arterial blood flow. The application of DCE-MRI scanning to quantitatively analyze the visual manifestations of microcirculation after early ONFH is an ideal method to study the microcirculation changes of necrotic femoral heads.
  • Effects of Technical Errors on the Outcomes of Operatively Managed Femoral Neck Fractures in Adults Less than 50 Years of Age. [Journal Article]
    J Orthop Trauma. 2023 Jan 05 [Online ahead of print]Collinge CA, Finlay A, … and Young Femoral Neck Fracture Working Group
  • CONCLUSIONS: TEs were found in half of all femoral neck fractures in young adults undergoing operative repair. Both the occurrence and number of TEs were associated with an increased risk for failure of treatment. preoperative planning for thoughtful and well-executed reduction and fixation techniques should lead to improved outcomes for young patients with femoral neck fractures. This study should also highlight the need for educational forums to address this subject.
  • Vertebral Body Osteonecrosis Mimicking Malignant Disease on 18F-FDG PET. [Case Reports]
    Clin Nucl Med. 2023 Mar 01; 48(3):e115-e117.Chaudhary K, Ngai S
  • We report a case of vertebral osteonecrosis after chemotherapy in a 24-year-old man with non-Hodgkin lymphoma, with transient avidity on 18F-FDG PET initially misinterpreted as recurrent extranodal disease. The patient demonstrated a partial metabolic response on midtreatment restaging PET; however, posttreatment PET showed an increase in uptake in T4 and T5 vertebrae, interpreted as recurrent ve…
  • The effect of drug holiday on preventing medication-related osteonecrosis of the jaw in osteoporotic rat model. [Journal Article]
    J Orthop Translat. 2023 Mar; 39:55-62.Zhu WY, Yang WF, … Su YX
  • CONCLUSIONS: Our data provided the first experimental evidence in the osteoporotic animal model that the implementation of a BP holiday in prior to dental extractions could partially recover osteoclastic activity, but could not alleviate the development of MRONJ-like lesion or exacerbate the osteoporotic condition in the femur. Longer-term drug holiday, or combination of drug holiday and other prophylaxes to prevent MRONJ in patients with osteoporosis could be worth exploring in future studies, to pave the way for clinical managements.
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