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(Bernard puncture)
181 results
  • Effect of landiolol on sex-related transcriptomic changes in the myocardium during sepsis. [Journal Article]
    Intensive Care Med Exp 2019; 7(1):50Tran TT, Mathieu C, … Lalevée N
  • CONCLUSIONS: In males, landiolol reversed the expression of many genes that were deregulated in sepsis. Conversely, sepsis-induced deregulation of gene expression was less pronounced in females than in males, and was maintained in the landiolol-treated females. These findings highlight important sex-related differences and confirm previous observations on the important benefit of landiolol intake on cardiac function in male rats.
  • Quantitative Ultrasound in Ex Vivo Fibrotic Rabbit Livers. [Journal Article]
    Ultrasound Med Biol 2019; 45(7):1777-1786Franceschini E, Escoffre JM, … Basset O
  • Liver fibrosis is the common result of chronic liver disease. Diagnosis and grading liver fibrosis for patient management is mainly based on blood tests and hepatic puncture-biopsy, which is particularly invasive. Quantitative ultrasound (QUS) techniques provide insight into tissue microstructure and are based on the frequency-based analysis of the signals from biologic tissues. This study aims t…
  • CD89 Is a Potent Innate Receptor for Bacteria and Mediates Host Protection from Sepsis. [Journal Article]
    Cell Rep 2019; 27(3):762-775.e5de Tymowski C, Heming N, … Ben Mkaddem S
  • Direct bacterial recognition by innate receptors is crucial for bacterial clearance. Here, we show that the IgA receptor CD89 is a major innate receptor that directly binds bacteria independently of its cognate ligands IgA and c-reactive protein (CRP). This binding is only partially inhibited by serum IgA and induces bacterial phagocytosis by CD11c+ dendritic cells and monocytes and/or macrophage…
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