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Unbound Medicine.
(Biomedical technology)
181,763 results
  • Linking whole-body angular momentum and step placement during perturbed walking. [Journal Article]
    J Exp Biol. 2023 Feb 08 [Online ahead of print]Leestma JK, Golyski PR, … Young AJ
  • Human locomotion is remarkably robust to environmental disturbances. Previous studies have thoroughly investigated how perturbations influence body dynamics and what recovery strategies are used to regain balance. Fewer studies have attempted to establish formal links between balance and the recovery strategies that are executed to regain stability. We hypothesized that there would be a strong re…
  • Photoswitchable semiconducting polymer dots for pattern encoding and superresolution imaging. [Journal Article]
    Chem Commun (Camb). 2023 Feb 08 [Online ahead of print]Yao Z, Wang X, … Fang X
  • Two photoswitchable semiconducting polymers were synthesized by covalently incorporating photochromic dithienylethene (DTE) into the main chains. Small size polymer dots (Pdots) were prepared and showed dynamic photoswitching upon alternate light irradiation. By virtue of the tunable photoswitching properties, effective pattern encoding and superresolution imaging with a resolution of up to about…
  • Capillary responses to functional and pathological activations rely on the capillary states at rest. [Journal Article]
    J Cereb Blood Flow Metab. 2023 Feb 08 [Online ahead of print]Suzuki H, Takeda H, … Masamoto K
  • Brain capillaries play a crucial role in maintaining cellular viability and thus preventing neurodegeneration. The aim of this study was to characterize the brain capillary morphology at rest and during neural activation based on a big data analysis from three-dimensional microangiography. Neurovascular responses were measured using a genetic calcium sensor expressed in neurons and microangiograp…
  • Optical coherence tomography. [Journal Article]
    Nat Rev Methods Primers. 2022; 2Bouma BE, de Boer JF, … Wojtkowski M
  • Optical coherence tomography (OCT) is a non-contact method for imaging the topological and internal microstructure of samples in three dimensions. OCT can be configured as a conventional microscope, as an ophthalmic scanner, or using endoscopes and small diameter catheters for accessing internal biological organs. In this Primer, we describe the principles underpinning the different instrument co…
  • Shining the light on mesenchymal stem cell-derived exosomes in breast cancer. [Review]
    Stem Cell Res Ther. 2023 Feb 08; 14(1):21.Al-Awsi GRL, Alsaikhan F, … Siahmansouri H
  • In women, breast cancer (BC) is the second most frequently diagnosed cancer and the leading cause of cancer death. Mesenchymal stem cells (MSCs) are a subgroup of heterogeneous non-hematopoietic fibroblast-like cells that have the ability to differentiate into multiple cell types. Recent studies stated that MSCs can migrate into the tumor sites and exert various effect on tumor growth and develop…
  • Comparing 2D and 3D representations for face-based genetic syndrome diagnosis. [Journal Article]
    Eur J Hum Genet. 2023 Feb 07 [Online ahead of print]Bannister JJ, Wilms M, … Forkert ND
  • Human genetic syndromes are often challenging to diagnose clinically. Facial phenotype is a key diagnostic indicator for hundreds of genetic syndromes and computer-assisted facial phenotyping is a promising approach to assist diagnosis. Most previous approaches to automated face-based syndrome diagnosis have analyzed different datasets of either 2D images or surface mesh-based 3D facial represent…
  • The role of digital technology in surgical home hospital programs. [Review]
    NPJ Digit Med. 2023 Feb 07; 6(1):22.Pathak K, Marwaha JS, Tsai TC
  • Home hospital (HH), a care delivery model of providing hospital-grade care to patients in their homes, has become increasingly common in medical settings, though surgical uptake has been limited. HH programs have been shown to be safe and effective in a variety of medical contexts, with increased usage of this care pathway during the COVID-19 pandemic. Though surgical patients have unique clinica…
  • Global health and global governance of emerging biomedical technologies. [Journal Article]
    J Med Ethics. 2023 Feb 07 [Online ahead of print]Cwik B
  • Global governance of emerging, disruptive biomedical technologies presents a multitude of ethical problems. The recent paper by Shozi et al raises some of these problems in the context of a discussion of what could be the most disruptive (and most morally fraught) emerging biomedical technology-human germline genome editing. At the heart of their argument is the claim that, for something like gen…
  • Divergent sensory and immune gene evolution in sea turtles with contrasting demographic and life histories. [Journal Article]
    Proc Natl Acad Sci U S A. 2023 Feb 14; 120(7):e2201076120.Bentley BP, Carrasco-Valenzuela T, … Komoroske LM
  • Sea turtles represent an ancient lineage of marine vertebrates that evolved from terrestrial ancestors over 100 Mya. The genomic basis of the unique physiological and ecological traits enabling these species to thrive in diverse marine habitats remains largely unknown. Additionally, many populations have drastically declined due to anthropogenic activities over the past two centuries, and their r…
  • Development of a Slow-Degrading Polymerized Curcumin Coating for Intracortical Microelectrodes. [Journal Article]
    ACS Appl Bio Mater. 2023 Feb 07 [Online ahead of print]Ziemba AM, Woodson MCC, … Gilbert RJ
  • Intracortical microelectrodes are used with brain-computer interfaces to restore lost limb function following nervous system injury. While promising, recording ability of intracortical microelectrodes diminishes over time due, in part, to neuroinflammation. As curcumin has demonstrated neuroprotection through anti-inflammatory activity, we fabricated a 300 nm-thick intracortical microelectrode co…
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