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(Breast Cancer)
393,925 results
  • The Two Faces of Relaxin in Cancer: Antitumor or Protumor? [Journal Article]
    Hepatology 2019Rizvi S, Gores GJ
  • The liver is one of the most common sites of metastatic disease from a variety of primary tumors including colorectal cancer, pancreatic ductal adenocarcinoma (PDAC), melanoma, breast cancer, and lung cancer. Moreover, metastatic disease to the liver is a leading cause of death in patients with malignancy. The liver has ample unique features favoring metastatic colonization by cancer (e.g. high b…
  • Advances in Endocrine-Based Therapies for Estrogen Receptor-Positive Metastatic Breast Cancer. [Review]
    Drugs 2019Aggelis V, Johnston SRD
  • Approximately 70% of breast cancers are estrogen-receptor positive. Tamoxifen and aromatase inhibitors have been the mainstay of endocrine therapy and have improved breast cancer survival. However, a large number of patients experience disease recurrence either during or following completion of endocrine therapy. Recent improvements in our understanding of the various mechanisms underlying the de…
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