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(Breast Cancer)
384,495 results
  • NCCN Guidelines Updates: Breast Cancer. [Journal Article]
  • JNJ Natl Compr Canc Netw 2019 May 01; 17(5.5):552-555
  • Telli ML, Gradishar WJ, Ward JH
  • Advances in molecular testing have ushered in the new era of precision medicine. The 2018 publication of the TAILORx trial helped refine the use of genetic expression assays, specifically the 21-gene…
  • Mitohormesis Primes Tumor Invasion and Metastasis. [Journal Article]
  • CRCell Rep 2019 May 21; 27(8):2292-2303.e6
  • Kenny TC, Craig AJ, … Germain D
  • Moderate mitochondrial stress can lead to persistent activation of cytoprotective mechanisms - a phenomenon termed mitohormesis. Here, we show that mitohormesis primes a subpopulation of cancer cells…
  • Reclassification of breast cancer: Towards improved diagnosis and outcome. [Journal Article]
  • PlosPLoS One 2019; 14(5):e0217036
  • Landry AP, Zador Z, … Cusimano MD
  • CONCLUSIONS: We have identified four distinct subgroups of breast cancer using LCA, including one unexpected group with good outcomes despite having the highest average histologic grade and rate of HR- tumours. Deeper understanding of subgroup characteristics can allow us to 1) identify actionable group properties relating to disease biology and patient features and 2) develop group-specific diagnostics and treatments.
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