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(CD34)
34,713 results
  • Onset of Appearance and Potential Significance of Telocytes in the Developing Fetal Lung. [Journal Article]
    Microsc Microanal 2019; :1-11Awad M, Gaber W, Ibrahim D
  • CD34, vimentin, and vascular endothelial growth factor immunohistochemical analysis and electron microscopic tools were employed to record the initial appearance of telocytes (TCs) and stage-by-stage variations in TC localizations in the developing rabbit lung. TCs could not be identified in the primitive embryonic lung until day 18 of gestation. In the pseudoglandular lung, CD34+ TCs had been re…
  • Only minor stem cell mobilization in head and neck irradiated patients treated with hyperbaric oxygen. [Journal Article]
    Diving Hyperb Med 2019; 49(3):175-185Forner L, Berkowicz A, … Fischer-Nielsen A
  • CONCLUSIONS: We found a minor statistically significant mobilizing effect of HBO treatment on the bone marrow derived stem/progenitor cell content in peripheral blood after 15 treatments (n = 10 patients), but no effect after 30 treatments (n = 6 patients). However, because of the low number of patients we cannot confidentially prove or disprove the null hypothesis. The possibility that HBO treatment reduces the number of activated platelets could not be demonstrated nor excluded.
  • Towards a scalable purification protocol of GaLV-TR pseudotyped lentiviral vectors. [Journal Article]
    Hum Gene Ther Methods 2019Boudeffa D, Bertin B, … Merten OW
  • Lentiviral vectors (LV) that are used in research and development as well as in clinical trials are in majority VSVg-pseudotyped. The predominance of this pseudotype choice for clinical gene therapy studies is largely due to a lack of purification schemes for pseudotypes other than VSVg. Here we report for the first time the development of a new downstream process (DSP) protocol allowing high yie…
  • Histological Corneal Alterations in Keratoconus After Crosslinking-Expansion of Findings. [Journal Article]
    Cornea 2019Müller PL, Loeffler KU, … Herwig-Carl MC
  • CONCLUSIONS: CXL may cause permanent keratocyte loss or repopulation of altered keratocytes, resulting in clinical complications such as corneal opacification or perforation. Despite its good safety profile and high effectiveness in progressive keratoconus, CXL should be performed in accordance with current guidelines strictly adhering to protocol and safety standards.
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