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Unbound Medicine.
(Cancer screening and prevention)
50,337 results
  • Awareness of the Adult Population Toward Colorectal Cancer in Qassim Region, Saudi Arabia. [Journal Article]
    Cureus. 2023 Jan; 15(1):e33477.Alsaigh S, Almuhaimeed FA, … Al-Mutairi HS
  • Introduction Colon and rectal cancer are usually grouped together as they share similar features. They are the third most common cancer in the world and the second most common cancer in the Kingdom of Saudi Arabia (KSA). Awareness and preventive screening programs play a vital role in early diagnosis and improving the survival rate of such patients. This study aimed to assess the awareness and kn…
  • Targeting Cbl-b in cancer immunotherapy. [Review]
    J Immunother Cancer. 2023 Feb; 11(2)Augustin RC, Bao R, Luke JJ
  • Cancer immunotherapy with immune-checkpoint blockade has improved the outcomes of patients with various malignancies, yet a majority do not benefit or develop resistance. To address this unmet need, efforts across the field are targeting additional coinhibitory receptors, costimulatory proteins, and intracellular mediators that could prevent or bypass anti-PD1 resistance mechanisms. The CD28 cost…
  • Variability Among Breast Cancer Risk Classification Models When Applied at the Level of the Individual Woman. [Journal Article]
    J Gen Intern Med. 2023 Feb 07 [Online ahead of print]Paige JS, Lee CI, … Elmore JG
  • CONCLUSIONS: Breast cancer risk estimates for individual women vary substantially, depending on which risk assessment model is used. The choice of cutoff used to define high risk can lead to adverse effects for screening, preventive care, and quality of life for misidentified individuals. Clinicians need to be aware of the high false-positive and false-negative rates and variation between models when talking with patients.
  • Scoping review protocol on the impact of antimicrobial resistance on cancer management and outcomes. [Journal Article]
    BMJ Open. 2023 Feb 06; 13(2):e068122.Bratti VF, Wilson BE, … Rodin D
  • Antimicrobial resistance (AMR) is a growing global public health concern and is becoming a significant challenge in the management of patients with cancer. Due to the immunosuppressive nature of cancer treatment, infection is a common complication and the necessary high usage of antibiotics increases the risk of AMR. Failure to adequately prevent and treat infection in patients with cancer as a r…
  • [Pancreatic cancer screening in a clinical practice setting: it is the moment of Prevention]. [Journal Article]
    Rev Gastroenterol Peru. 2022 Oct-Dec; 42(4):234-241.Adán-Merino L, Mora-Soler A, … Ponferrada-Diaz Á
  • Pancreatic cancer surveillance can improve outcomes in high-risk individuals. However, little is known about its applicability and findings in routine clinical practice. Our aim was to evaluate findings on screening tests in high-risk individuals in a clinical practice setting and to analyze factors associated with the presence of relevant pancreatic lesions. We developed a prospective observatio…
  • Early cervical cancer screening: The influence of culture and religion. [Journal Article]
    Afr J Prim Health Care Fam Med. 2023 Jan 25; 15(1):e1-e6.Gutusa F, Roets L
  • CONCLUSIONS: According to the study findings, culture and religion constitute impediments to early cervical cancer screening for rural women. Interventions that encourage screening, such as targeted health education and health promotion materials, must consider cultural and religious views if behaviour change in diverse groups is to be accomplished.Contribution: The study has the potential to inform Zimbabwean health policy and contribute to prospective interventions or health education that encourage women to attend early cancer screening.
  • Cervical HPV infection in Guangzhou, China: an epidemiological study of 198,111 women from 2015 to 2021. [Journal Article]
    Emerg Microbes Infect. 2023 Feb 06 [Online ahead of print]Yang X, Li Y, … Luo M
  • Persistent high-risk human papillomavirus (HPV) infection is the pivotal cause of cervical carcinogenesis. HPV types distribution varies greatly by region, and its long-term changes of prevalence remain to be fully characterized in China. Here, the largest population of 198,111 consecutive women who underwent routine cervical screening were investigated from 2015 to 2021 in Guangzhou, south China…
  • Significant outcomes associated with high-risk human papillomavirus negative Papanicolaou tests. [Journal Article]
    J Am Soc Cytopathol. 2023 Jan 11 [Online ahead of print]Karaaslan S, Dilcher TL, … Goyal A
  • CONCLUSIONS: With widespread adoption of risk-based approach to management, the role of cytology, by itself, will likely diminish in the detection of HPV-associated lesions. Additional data regarding the role of cytology in the screening of patients with no/unknown/limited history and in the detection/management of HPV-independent lesions may be helpful for designing future screening guidelines.
  • Screening Chest CT Prior to Allogenic Hematopoietic Stem Cell Transplantation. [Journal Article]
    Transplant Cell Ther. 2023 Feb 02 [Online ahead of print]Alhomoud M, Chokr N, … Van Besien K
  • Pulmonary complications constitute a major cause of morbidity and mortality in the post-allogenic hematopoietic stem cell transplant (alloHSCT) period. While Chest X-ray (CXR) is customarily used for screening, we have utilized chest computed tomography (CT). To characterize the prevalence of abnormalities and explore their impact on alloHSCT eligibility and outcomes post-transplant, we conducted…
  • Knowledge and awareness of colorectal cancer among a predominantly Indigenous Caribbean community. [Journal Article]
    BMC Public Health. 2023 Feb 04; 23(1):243.Warner ZC, Gilbert-Gard K, … Warner EL
  • CONCLUSIONS: Despite limited familiarity with CRC screening, participants broadly believed CRC screening to be important. Health education research is needed to develop patient-centered, culturally appropriate materials about CRC screening and prevention. Future work facilitating productive community partnerships and incorporating prevailing community traditions may align cancer prevention and education initiatives with community priorities.
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