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339,061 results
  • The gut-liver axis in liver disease: pathophysiological basis for therapy. [Review]
    J Hepatol 2019Albillos A, Gottardi A, Rescigno M
  • The gut-liver axis refers to the bidirectional relationship between the gut and its microbiota, and the liver, resulting from the integration of signals generated by dietary, genetic and environmental factors. This reciprocal interaction is established through the vascular route of the portal vein that carries gut-derived products directly to the liver, and the liver feed-back route of bile and a…
  • Architecture of population-differentiated polymorphisms in the human genome. [Journal Article]
    PLoS One 2019; 14(10):e0224089Bachtiar M, Jin Y, … Lee CGL
  • Population variation in disease and other phenotype are partly attributed to single nucleotide polymorphisms (SNPs) in the human genome. Due to selection pressure, two individuals from the same ancestral population have more genetic similarity compared to individuals from further geographic regions. Here, we elucidated the genomic population differentiation pattern, by interrogating >22,000,000 S…
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