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(Coats disease)
2,103 results
  • Why do humans get acne? A hypothesis. [Journal Article]
    Med Hypotheses 2019; 134:109412Shannon JF
  • Acne is a disease unique to humans and is associated with sebaceous glands that are found at high density on the scalp, forehead and face. Despite being a near universal problem in adolescence, the reason why such troublesome sebaceous glands exist at all is not well understood. Some interesting theories have been postulated including roles for skin maintenance, immunological function and perhaps…
  • Autonomous early detection of eye disease in childhood photographs. [Journal Article]
    Sci Adv 2019; 5(10):eaax6363Munson MC, Plewman DL, … Shaw BF
  • The "red reflex test" is used to screen children for leukocoria ("white eye") in a standard pediatric examination, but is ineffective at detecting many eye disorders. Leukocoria also presents in casual photographs. The clinical utility of screening photographs for leukocoria is unreported. Here, a free smartphone application (CRADLE: ComputeR-Assisted Detector of LEukocoria) was engineered to det…
  • [Infant with intracranial calcifications and retinopathy]. [Case Reports]
    Rev Neurol 2019; 69(7):289-292Hidalgo-Sanz J, Perez-Delgado R, … Izquierdo-Alvarez S
  • CONCLUSIONS: Coats plus syndrome is an extraordinarily rare autosomal recessive disease, caused by mutations in the CTC1 gene, which involves the appearance of retinal telangiectasias, brain cysts, calcifications in deep nuclei and leukoencephalopathy, as well as other bone and gastrointestinal conditions. Treatment is symptomatic and the disease has a poor prognosis.
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