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(Cohnheim Julius Friedrich)
34 results
  • Paul Ehrlich and the Early History of Granulocytes. [Historical Article]
    Microbiol Spectr 2016; 4(4)Kay AB
  • Paul Ehrlich's techniques, published between 1879 and 1880, for staining blood films using coal tar dyes, and his method of differential blood cell counting, ended years of speculation regarding the classification of white cells. Acidic and basic dyes had allowed him to recognize eosinophil and basophil granules, respectively, work that was a direct continuation of his discovery of the tissue mas…
  • Absolute and Relative Activity Values in Assessing the Effect of NADPH Oxidase Inhibitors. [Letter]
    Antioxid Redox Signal 2015; 23(15):1250-1Pick E
  • This Letter addresses the following publication: Hirano K, Chen, WS, Chueng ALW, Dunne AA, Seredenina T, Filippova T, Ramachandran S, Bridges A, Chaudry L, Pettman G, Allan C, Duncan S, Lee KC, Lim J, Ma MT, Ong AB, Ye NY, Nasir S, Mulyanidewi S, Aw CC, Oon PP, Liao S, Li D, Johns DG, Miller ND, Davies CH, Browne ER, Matsuoka Y, Chen DW, Jaquet V, and Rutter AR. Discovery of GSK2795039, a novel s…
  • Cell-free NADPH oxidase activation assays: "in vitro veritas". [Journal Article]
    Methods Mol Biol 2014; 1124:339-403Pick E
  • The superoxide (O2 (∙-))-generating NADPH oxidase complex of phagocytes comprises a membrane-imbedded heterodimeric flavocytochrome, known as cytochrome b 558 (consisting of Nox2 and p22 (phox)) and four cytosolic regulatory proteins, p47 (phox) , p67 (phox) , p40 (phox) , and the small GTPase Rac. Under physiological conditions, in the resting phagocyte, O2 (∙-) generation is initiated by engage…
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