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24,741 results
  • Pediatricians lack knowledge for the diagnosis and management of functional constipation in children over 6 mo of age. [Journal Article]
  • WJWorld J Clin Pediatr 2018 Feb 08; 7(1):56-61
  • Widodo A, Hegar B, Vandenplas Y
  • CONCLUSIONS: These data provide an insight on the diagnosis and management of constipation in childhood in Indonesia. Although general pediatricians are aware of some important aspects of the diagnosis and mangement of constipation, overall knowledge is limited. Efforts should be made to improve the distribution of existing guidelines. These findings highlight and confirm the difficulties in spreading existing information from guidelines to general pediatricians.
  • Fecal markers of intestinal inflammation and intestinal permeability are elevated in Parkinson's disease. [Journal Article]
  • PRParkinsonism Relat Disord 2018 Feb 12
  • Schwiertz A, Spiegel J, … Unger MM
  • CONCLUSIONS: Fecal markers reflecting intestinal inflammation and increased intestinal permeability have been primarily investigated in inflammatory bowel disease so far. Our data indicate that calprotectin, alpha-1-antitrypsin and zonulin could be useful non-invasive markers in PD as well. Even though these markers are not disease-specific, they corroborate the hypothesis of an intestinal inflammation as contributing factor in the pathogenesis of PD. Further investigations are needed to determine whether calprotectin, alpha-1-antitrypsin and zonulin can be used to define PD subgroups and to monitor the effect of interventions in PD.
  • Parent-reported prevalence and persistence of 19 common child health conditions. [Journal Article]
  • ADArch Dis Child 2018 Feb 16
  • Liu T, Lingam R, … Wake M
  • CONCLUSIONS: Beyond infancy, most Australian children are experiencing at least one ongoing health condition at any given time. This study's age-specific estimates of prevalence and persistence should assist families and clinicians to plan care. Conditions showing little resolution (obesity, asthma, attention-deficit hyperactivity disorder) require long-term planning and management.
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