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422,912 results
  • Unicuspid Aortic Valve Repair using Geometric Ring Annuloplasty. [Journal Article]
    Ann Thorac Surg. 2020 Jun 30 [Online ahead of print]Si MS, Conte JV, … Turek JW
  • CONCLUSIONS: Aortic ring annuloplasty reduced annular diameter effectively, recruiting more leaflet to mid-line coaptation. Minor fusion commissurotomy and annular remodeling to 180° commissures converted UAV repair to a simple and reproducible procedure.
  • Coupling Neuropeptide Levels to Structural Plasticity in Drosophila Clock Neurons. [Journal Article]
    Curr Biol. 2020 Jun 29 [Online ahead of print]Herrero A, Yoshii T, … Ceriani MF
  • We have previously reported that pigment dispersing factor (PDF) neurons, which are essential in the control of rest-activity cycles in Drosophila, undergo circadian remodeling of their axonal projections, a phenomenon called circadian structural plasticity. Axonal arborizations display higher complexity during the day and become simpler at night, and this remodeling involves changes in the degre…
  • Thiosulfinate Tolerance Is a Virulence Strategy of an Atypical Bacterial Pathogen of Onion. [Journal Article]
    Curr Biol. 2020 Jun 26 [Online ahead of print]Stice SP, Thao KK, … Kvitko BH
  • Unlike most characterized bacterial plant pathogens, the broad-host-range plant pathogen Pantoea ananatis lacks both the virulence-associated type III and type II secretion systems. In the absence of these typical pathogenicity factors, P. ananatis induces necrotic symptoms and extensive cell death in onion tissue dependent on the HiVir proposed secondary metabolite synthesis gene cluster. Onion …
  • Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides. [Journal Article]
    Cell Chem Biol. 2020 Jun 30 [Online ahead of print]Keenan T, Parmeggiani F, … Fascione MA
  • Fluorinated sugar-1-phosphates are of emerging importance as intermediates in the chemical and biocatalytic synthesis of modified oligosaccharides, as well as probes for chemical biology. Here we present a systematic study of the activity of a wide range of anomeric sugar kinases (galacto- and N-acetylhexosamine kinases) against a panel of fluorinated monosaccharides, leading to the first example…
  • Conditional Survival after Surgery for Patients with Penile Cancer. [Journal Article]
    Andrology. 2020 Jul 03 [Online ahead of print]Liu W, Luo Y, … Wang X
  • CONCLUSIONS: The survival probability of SCCP patients increases with postoperative survival. Patients with aggressive disease at baseline ultimately benefit the most from event-free survivorship and may expect a better prognosis once they survive the critical few years after surgery. The recorded observations have crucial implications regarding patient counseling and follow-up.
  • Rhodium(iii)-catalyzed diamidation of olefins via amidorhodation and further amidation. [Journal Article]
    Chem Commun (Camb). 2020 Jul 03 [Online ahead of print]Wang J, Zheng G, Li X
  • Rh(iii)-catalyzed synthesis of vicinal diamides has been realized via elaboration of an authenticated Rh-C(sp3) species generated via initial intramolecular amidorhodation of olefins. The second amidation was achieved using both electrophilic and nucleophilic amidating reagents. The reactions proceeded under mild conditions with good yield, broad substrate scope, and excellent functional-group to…
  • GammaTile®: Surgically targeted radiation therapy for glioblastomas. [Journal Article]
    Future Oncol. 2020 Jul 03 [Online ahead of print]Gessler DJ, Ferreira C, … Chen CC
  • Glioblastoma is the most common primary malignant neoplasm of the central nervous system in adults. Standard of care is resection followed by chemo-radiation therapy. Despite this aggressive approach, >80% of glioblastomas recur in proximity to the resection cavity. Brachytherapy is an attractive strategy for improving local control. GammaTile® is a newly US FDA-cleared device which incorporates …
  • Rapid and Large-area Visualization of Grain Boundaries in MoS2 on SiO2 Using Vapor Hydrofluoric Acid. [Journal Article]
    ACS Appl Mater Interfaces. 2020 Jul 03 [Online ahead of print]Fan X, Siris R, … Niklaus F
  • Grain boundaries in 2D material layers are impacting their electrical, optoelectronic and mechanical properties. Therefore, the availability of simple large-area characterization approaches that can directly visualize grains and grain boundaries in 2D materials such as molybdenum disulfide (MoS2) is critical. Previous approaches for visualizing grains and grain boundaries in MoS2 are typically ba…
  • Automated Glycan Assembly of Plant Cell Wall Oligosaccharides. [Journal Article]
    Methods Mol Biol. 2020; 2149:503-512.Pfrengle F
  • Synthetic cell wall oligosaccharides are promising molecular tools for investigating the structure and function of plant cell walls. Their well-defined structure and high purity prevents misinterpretations of experimental data, and the possibility to introduce chemical handles provides means for easier localization and detection. Automated glycan assembly as emerged has a powerful new method for …
  • Synthesis of Various Size Gold Nanoparticles by Chemical Reduction Method with Different Solvent Polarity. [Journal Article]
    Nanoscale Res Lett. 2020 Jul 02; 15(1):140.Hussain MH, Abu Bakar NF, … Adam F
  • Complicated and strict protocols are followed to tune the size of gold nanoparticles (GNPs) in chemical synthesis methods. In this study, we address the polarity of solvents as a tool for tailoring the size of GNPs in the chemical reduction method. The effects of varying polarity index of the reaction medium on synthesizing gold nanoparticles by chemical reduction method have been investigated. E…
  • Near-infrared photothermal liposomal nanoantagonists for amplified cancer photodynamic therapy. [Journal Article]
    J Mater Chem B. 2020 Jul 03 [Online ahead of print]Sun H, Feng M, … Wang X
  • Photodynamic therapy (PDT) has been demonstrated to be a promising strategy for the treatment of cancer, while its therapeutic efficacy is often compromised due to excessive concentrations of glutathione (GSH) as a reactive oxygen species (ROS) scavenger in cancer cells. Herein, we report the development of near-infrared (NIR) photothermal liposomal nanoantagonists (PLNAs) for amplified PDT throu…
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