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404,198 results
  • Gold nanocubes embedded biocompatible hybrid hydrogels for electrochemical detection of H2O2. [Journal Article]
    Bioelectrochemistry 2019; 131:107373Manickam P, Vashist A, … Nair M
  • Smart electrochemical biosensors have emerged as a promising alternative analytical diagnostic tool in recent clinical practice. However, improvement in the biocompatibility and electrical conductivity of the biosensor matrix and the immobilization of various bioactive molecules such as enzymes still remain challenging. The present research reports the synthesis of a biocompatible hydrogel networ…
  • Genome engineering of E. coli for improved styrene production and polymerization. [Journal Article]
    Metab Eng 2019Liang L, Liu R, … Gill RT
  • Microbial production of exogenous organic compounds is challenging as biosynthetic pathways are often complex and produce metabolites that are toxic to the hosts. Biogenic styrene is an example of this problem, which if addressed could result in a more sustainable supply of this important component of the plastics industry. In this study, we engineered Escherichia coli for the production of styre…
  • Ciprofibrate attenuates airway remodeling in cigarette smoke-exposed rats. [Journal Article]
    Respir Physiol Neurobiol 2019; :103290Ke Q, Yang L, … He B
  • Airway remodeling is a key pathological lesion in chronic obstructive pulmonary disease (COPD), and it leads to poorly reversible airway obstruction. Current pharmacological interventions are ineffective at controlling airway remodeling. To address this issue, we queried the Connectivity Map (cMap) database to screen for drug candidates that had the potential to dilate the bronchus and inhibit ai…
  • New look for an old molecule - Solid/solid phase transition in cholesterol monolayers. [Journal Article]
    Chem Phys Lipids 2019; :104819Rodríguez JLF, Caseli L, … Dynarowicz-Latka P
  • Surface pressure (π) - molecular area (A) isotherms of cholesterol were precisely measured to get insight into the orientation of molecules in Langmuir monolayers, which allowed to obtain detailed information on their phase behaviour. This was possible from the detailed analysis of the interfacial compressibility modulus versus surface pressure (Cs-1- π) plots (obtained from the experimental surf…
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