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2,577 results
  • Treatment of trichotillomania and subthreshold bipolar disorder with lithium. [Journal Article]
    Bipolar Disord 2019Sharma V
  • A 26-year old single, unemployed, mother of a nine year old boy was referred by her family physician for assessment of recurrent depression. She had been treated with duloxetine 30 mg-90 mg over the past five years. The medication was initially effective; however, in spite of its regular use she had continued to experience frequent episodes of depression of progressively increasing severity.
  • Prolonged acidosis is a feature of SGLT2i-induced euglycaemic diabetic ketoacidosis. [Journal Article]
    Endocrinol Diabetes Metab Case Rep 2019; 2019Rafey MF, Butt A, … Finucane FM
  • We describe two cases of SGLT2i-induced euglycaemic diabetic ketoacidosis, which took longer than we anticipated to treat despite initiation of our DKA protocol. Both patients had an unequivocal diagnosis of type 2 diabetes, had poor glycaemic control with a history of metformin intolerance and presented with relatively vague symptoms post-operatively. Neither patient had stopped their SGLT2i pre…
  • Pharmacological Treatment of Chemotherapy-Induced Neuropathic Pain: PPARγ Agonists as a Promising Tool. [Review]
    Front Neurosci 2019; 13:907Quintão NLM, Santin JR, … Costa R
  • Chemotherapy-induced neuropathic pain (CINP) is one of the most severe side effects of anticancer agents, such as platinum- and taxanes-derived drugs (oxaliplatin, cisplatin, carboplatin and paclitaxel). CINP may even be a factor of interruption of treatment and consequently increasing the risk of death. Besides that, it is important to take into consideration that the incidence of cancer is incr…
  • Nabilone for the Treatment of Post-Traumatic Stress Disorder: A Review of Clinical Effectiveness and Guidelines [BOOK]
    Canadian Agency for Drugs and Technologies in Health: Ottawa (ON) Cowling Tara T MacDougall Danielle D BOOK
  • Post-traumatic stress disorder (PTSD) is characterized by substantial psychological or physiological distress following exposure to trauma.1 According to the most recent Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), criteria for PTSD diagnosis includes either direct, or indirect (e.g., as a witness, or having learned that a close family member or friend has experie…
  • What do patients learn about psychotropic medications on the web? A natural language processing study. [Journal Article]
    J Affect Disord 2019; 260:366-371Hart KL, Perlis RH, McCoy TH
  • CONCLUSIONS: While these results provide a novel means of comparing medications, the present analyses cannot be linked to individual patient consumption of this information, or to its influence on their future clinical interactions.Overall, a subset of psychotropic medications were associated with significantly more negative sentiment. Characterizing these differences may allow clinicians to anticipate patient willingness to initiate or continue medications.
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