- The rapid anxiety screening study-pilot data. [Journal Article]J Investig Med. 2023 Feb 08 [Online ahead of print]JI
- Anxiety disorders are the most common mental health condition in the United States. Medical providers often have many active issues when treating a patient, and do not always have time for a thorough psychiatric evaluation. The Patient Health Questionnaire 2, a two-question binary (yes/no) screening tool, has been developed to address these issues in the identification of unipolar depression. No …
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- Cognitive performance and brain structural connectome alterations in major depressive disorder. [Journal Article]Psychol Med. 2023 Feb 08 [Online ahead of print]PM
- CONCLUSIONS: Our study is the first to identify cognition-related structural brain networks in MDD patients, thereby revealing associations between cognitive deficits, depressive symptoms, and reduced structural connectivity. This supports the hypothesis that structural connectome alterations may mediate the association of cognitive deficits and depression severity.
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- [Depressive Disorders in Adolescence: Current State of Studies Concerning the Microbiota-Gut-Brain Axis]. [Review]Z Kinder Jugendpsychiatr Psychother. 2023 Feb 08 [Online ahead of print]ZK
- Depressive Disorders in Adolescence: Current State of Studies Concerning the Microbiota-Gut-Brain Axis Abstract. Depressive disorders increase during adolescence and often lead to significant impairment in affected individuals - despite treatment. Current research efforts aim to further investigate the pathophysiology of depression, considering the influence of gut microbiota on the gut-brain axi…
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- Loneliness-a clinical primer. [Journal Article]Br Med Bull. 2023 Feb 07 [Online ahead of print]BM
- CONCLUSIONS: due to increased individualization and incidence of infectious diseases, loneliness is likely to become even more prevalent.more research is needed to further elucidate the health impacts of loneliness as well as to find evidence-based interventions to prevent and mitigate loneliness that could then be implemented by policy-makers and clinicians.
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- Prediabetes and the risk of type 2 diabetes: investigating the roles of depressive and anxiety symptoms in the Lifelines Cohort Study. [Journal Article]Diabet Med. 2023 Feb 08 [Online ahead of print]DM
- CONCLUSIONS: Individuals with elevated depressive, and to some extent anxiety, symptoms in combination with prediabetes may represent a high-risk subgroup for type 2 diabetes.
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- Baseline characteristics of the North American prodromal Synucleinopathy cohort. [Journal Article]Ann Clin Transl Neurol. 2023 Feb 08 [Online ahead of print]AC
- CONCLUSIONS: These RBD participants, assessed with extensive history, demographic, cognitive, motor, sensory, and autonomic function demonstrated a lack of sex differences and high frequency of concomitant neurological abnormalities. These participants will be valuable for future longitudinal study and neuroprotective clinical trials.
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- Which type of female urinary incontinence has more impact on pelvic floor and sexual function in addition to anxiety and depression symptoms: A questionnaire-based study. [Journal Article]Neurourol Urodyn. 2023 Feb 07 [Online ahead of print]NU
- CONCLUSIONS: The sexual dysfunction and psychological symptoms were found to be similar in the patients according to UI type. The MUI patients were seen to have more incontinence symptoms compared to the other types and experienced more pelvic floor dysfunction than patients with UUI.
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- Physical and mental health status of former smokers and non-smokers patients with bipolar disorder. [Journal Article]Acta Psychiatr Scand. 2023 Feb 07 [Online ahead of print]AP
- CONCLUSIONS: Tobacco smoking was associated with high morbidity level. Strikingly, as in the general population, quitting smoking seemed associated with their return to the never-smokers' levels. Our findings strongly highlight the need to spread strategies to treat tobacco addiction in the BD population.
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- Death-associated protein kinase 1 is associated with cognitive dysfunction in major depressive disorder. [Journal Article]Neural Regen Res. 2023 Aug; 18(8):1795-1801.NR
- We previously showed that death-associated protein kinase 1 (DAPK1) expression is increased in hippocampal tissue in a mouse model of major depressive disorde and is related to cognitive dysfunction in Alzheimer's disease. In addition, depression is a risk factor for developing Alzheimer's disease, as well as an early clinical manifestation of Alzheimer's disease. Meanwhile, cognitive dysfunction…
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- Splenectomy does not affect mouse behaviors. [Journal Article]Neural Regen Res. 2023 Aug; 18(8):1789-1794.NR
- The spleen is critical for immunity. It is the largest immune organ and immune center in the peripheral system. While the relationship between behavior and immunity has been demonstrated in physiology and diseases, the role of the spleen in behavior is not clear. To investigate the effects of the spleen on behaviors, we performed a refined splenectomy procedure on C57BL/6J mice and performed an o…
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- Sphingosine 1-phosphate receptor 1 regulates blood-brain barrier permeability in epileptic mice. [Journal Article]Neural Regen Res. 2023 Aug; 18(8):1763-1769.NR
- Destruction of the blood-brain barrier is a critical component of epilepsy pathology. Several studies have demonstrated that sphingosine 1-phosphate receptor 1 contributes to the modulation of vascular integrity. However, its effect on blood-brain barrier permeability in epileptic mice remains unclear. In this study, we prepared pilocarpine-induced status epilepticus models and pentylenetetrazol-…
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- Individuals' Coping Styles and Levels of Depression, Anxiety, and Stress During the COVID-19 Pandemic in Turkey: A Web-Based Cross-Sectional Study. [Journal Article]Sage Open. 2023 Jan-Mar; 13(1):21582440221148628.SO
- This cross-sectional study aimed to determine the correlation between the coping styles and depression, anxiety, and stress levels of individuals living in Turkey during the COVID-19 pandemic. The study was conducted using an online questionnaire (Socio-demographic Form; Depression, Anxiety, and Stress Scale-21; Coping Styles Scale) and it included 483 individuals. Descriptive statistics, ANOVA, …
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- Establishment and verification of a nomogram model for predicting the risk of post-stroke depression. [Journal Article]PeerJ. 2023; 11:e14822.P
- CONCLUSIONS: This novel nomogram, which combines patients' work style, number of children, time from onset to hospitalization, history of hyperlipidemia, stroke area, and NIHSS score, can help clinicians to assess the risk of depression in patients with acute stroke much earlier in the timeline of the disease, and to implement early intervention treatment so as to reduce the incidence of PSD.
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- Three-dimensional quantitative analysis of temporal region morphology in Chinese young adult. [Journal Article]PeerJ. 2023; 11:e14226.P
- CONCLUSIONS: The method has high overlap and good repeatability and minimizes the influence of subjective aesthetics on morphological judgment. TDV has a certain reference value for clinical temporal region evaluation.
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- Mental-Health Trajectories of U.S. Parents With Young Children During the COVID-19 Pandemic: A Universal Introduction of Risk. [Journal Article]Clin Psychol Sci. 2023 Jan; 11(1):183-196.CP
- Parents of young children were a subgroup of the population identified early in the pandemic as experiencing significant mental-health symptoms. Using a longitudinal sample of 3,085 parents from across the United States who had a child or children age 0 to 5, in the present study, we identified parental mental-health trajectories from April to November 2020 predicted by pre-COVID-19 cumulative ri…
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- Improved lifestyle is associated with improved depression, anxiety and well-being over time in UK healthcare professionals during the COVID-19 pandemic: insights from the CoPE-HCP cohort study. [Journal Article]Gen Psychiatr. 2023; 36(1):e100908.GP
- CONCLUSIONS: Improved lifestyle over time is associated with improved mental health and mental well-being in HCPs during the pandemic. Improving lifestyle could be a recommended intervention for HCPs to help mitigate the mental health impact during the current and future pandemics.
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- The role of assessment of renal biopsy in electron microscopy in making a diagnosis of juvenile-onset systemic lupus erythematosus in a 16-year-old female patient with depression and proteinuria - a case report. [Case Reports]Cent Eur J Immunol. 2022; 47(2):175-178.CE
- The course of juvenile-onset systemic lupus erythematosus may vary, from rapid multiorgan involvement to insidious development mimicking different medical conditions. Depressive disorder in adolescents poses considerable diagnostic difficulties due to the natural tendency to lowered mood in this age group. However, it may also be the manifestation of a systemic disease. We present a case of a 16-…
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- Complex psychiatric comorbidities in Thai trans women: A case series. [Case Reports]F1000Res. 2022; 11:74.F
- Trans women (TW) have a high prevalence of poor mental health. Gender-affirming treatments could reduce distress regarding their gender incongruity. However, psychiatric comorbidities might complicate the management or even confirmation of being transgender. We reported three TW with complex mental illnesses, including anxiety disorder with cultural explanation, neurodevelopmental disorders with …
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- Long-Term Yogic Intervention Improves Symptomatic Scale and Quality of Life by Reducing Inflammatory Cytokines and Oxidative Stress in Breast Cancer Patients Undergoing Chemotherapy and/or Radiotherapy: A Randomized Control Study. [Journal Article]Cureus. 2023 Jan; 15(1):e33427.C
- CONCLUSIONS: These findings suggest that yoga may reduce levels of inflammatory cytokines and improve QoL and symptomatic scale in breast cancer patients receiving chemotherapy and/or radiotherapy. Yoga can be an important additional therapy during cancer treatments to cope with treatment side effects including fatigue, depression, and immunological profile, which directly affects the patient's quality of life.
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- Evaluation of Psychiatric Comorbidities and Quality of Life As Well As Brain-Derived Neurotrophic Factor (BDNF) Concentrations Among Patients Suffering From Acne Vulgaris: A Systematic Review and Meta-Analysis. [Review]Cureus. 2023 Jan; 15(1):e33357.C
- Acne vulgaris usually affects the dermal layer of the skin and is revealed frequently in young adulthood and adolescence. It has serious psychosocial comorbidities. We conducted the present systematic review and meta-analysis to elucidate the association of acne vulgaris with psychiatric comorbidities and quality of life as well as the brain-derived neurotrophic factor (BDNF) level. A systematic …
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- Age-related differences in social media use, online social support, and depressive symptoms in adolescents and emerging adults. [Journal Article]Child Adolesc Ment Health. 2023 Feb 07 [Online ahead of print]CA
- CONCLUSIONS: Results suggest overall developmental changes in social media use and that adolescents may be more susceptible than emerging adults to the beneficial effects of positive online interactions on mental health.
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- Quality of life and nurse-patient interaction among NH residents: Loneliness is detrimental, while nurse-patient interaction is fundamental. [Journal Article]J Clin Nurs. 2023 Feb 07 [Online ahead of print]JC
- CONCLUSIONS: This study suggests that loneliness is frequent as well as more detrimental to quality-of-life among nursing home residents compared to anxiety and depression. Furthermore, the present results show that the nurse-patient interaction represents an essential health-promoting resource for Quality-of-life in this population.
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- Acceptance and commitment therapy for people with acquired brain injury: Rationale and description of the BrainACT treatment. [Journal Article]Clin Rehabil. 2023 Feb 07 [Online ahead of print]CR
- CONCLUSIONS: Existing evidence-based protocols were adapted for the needs and potential cognitive deficits after brain injury. General alterations are the use of visual materials, summaries and repetition. Acceptance and commitment therapy-specific adaptions include the Bus of Life metaphor as a recurrent exercise, shorter mindfulness exercises, simplified explanations, a focus on experiential exercises and the monitoring of committed actions. The intervention consists of eight one-hour sessions with a psychologist, experienced in acceptance and commitment therapy and in working with people with acquired brain injury. The order of the sessions, metaphors and exercises can be tailored to the needs of the patients.Currently, the effectiveness and feasibility of the intervention is evaluated in a randomised controlled trial. The BrainACT intervention is expected to be a feasible and effective intervention for people with anxiety or depressive symptoms following acquired brain injury.
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- Associations between changes in physical activity and perceived social exclusion and loneliness within middle-aged adults - longitudinal evidence from the German ageing survey. [Journal Article]BMC Public Health. 2023 Feb 07; 23(1):274.BP
- CONCLUSIONS: In middle-aged adults, longitudinal associations were found for physical activity and perceived social exclusion. Perceived social exclusion may be prevented by maintaining at least 150 min of moderate physical activities per week, which is the WHO physical activity recommendation. Future research should investigate moderators and mediators in the association between physical activity and social exclusion as well as loneliness.
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- Depressive symptoms and physical activity among community-dwelling perimenopausal women: a prospective longitudinal study. [Journal Article]BMC Psychiatry. 2023 Feb 07; 23(1):93.BP
- CONCLUSIONS: The cross-lagged panel model disclosed longitudinal bidirectional relationships between depressive symptoms and physical activity in perimenopausal women. Appropriate physical activity should be recommended for perimenopausal women to improve their mental well-being. Tailored physical activity duration and maintenance measures should be proposed based on different sociodemographic statuses.
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- Multi-omics data reveals the important role of glycerophospholipid metabolism in the crosstalk between gut and brain in depression. [Journal Article]J Transl Med. 2023 Feb 07; 21(1):93.JT
- CONCLUSIONS: Our results provided novel perceptions on the role of Gut-Liver-Brain axis in the onset of depression, and showed that GP metabolism might be the bridge between gut microbiota and depression. "Lachnospiraceae-GP metabolism-GABA" held the promise as a potential way between gut microbiota and brain functions in DM.
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- The effects of Digital Buddy programme on older adults' mental well-being: study protocol for a multi-centre, cluster randomized controlled trial. [Journal Article]Trials. 2023 Feb 07; 24(1):95.T
- Mental well-being is associated with many mental health symptoms, including depression and health-related quality of life. Digital divide could impact mental health, particularly during the COVID-19 pandemic. Information and communication technology (ICT)-based tools and interventions could effectively provide social support. Intergenerational mentoring between college students and older adults c…
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- Potential molecular mechanisms of chronic fatigue in long haul COVID and other viral diseases. [Review]Infect Agent Cancer. 2023 Feb 07; 18(1):7.IA
- Historically, COVID-19 emerges as one of the most devastating diseases of humankind, which creates an unmanageable health crisis worldwide. Until now, this disease costs millions of lives and continues to paralyze human civilization's economy and social growth, leaving an enduring damage that will take an exceptionally long time to repair. While a majority of infected patients survive after mild …
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- Emotional eating in relation to psychological stress during COVID-19 pandemic: a cross-sectional study in faculty of medicine, Tanta University, Egypt. [Journal Article]BMC Public Health. 2023 Feb 07; 23(1):277.BP
- CONCLUSIONS: COVID-19 pandemic, particularly during the period of lockdown, had a negative impact on individuals' psychological stress levels and levels of emotional eating behaviors.
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- Facilitators and barriers in the development and implementation of depression prevention and treatment policies in China: a qualitative study. [Journal Article]BMC Public Health. 2023 Feb 07; 23(1):276.BP
- CONCLUSIONS: Although the process of implementing a distinctive service programme for depression prevention and treatment in China has been long, the current policy is in line with current global efforts. Strategies to reduce Stigma and increase knowledge about depression are part of a national and international approach to reducing the burden of depression. Political commitment and the involvement of all stakeholders remain necessary. An adequate response to depression will require the involvement of society as a whole, with joint action to reduce the risk of exposure to adversity and enhance protective factors.
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