- Civilian Gunshot Wounds to the Head. Prognostic Factors affecting Mortality. Meta-Analysis of 1774 patients. [Journal Article]
- JNJ Neurotrauma 2018 Jun 07
- Civilian gunshot wounds to the head (cGSWH) are devastating, but there is no consensus regarding prognosis and management. Therefore, we conducted a meta-analysis to identify prognostic factors assoc...
Civilian gunshot wounds to the head (cGSWH) are devastating, but there is no consensus regarding prognosis and management. Therefore, we conducted a meta-analysis to identify prognostic factors associated with mortality. PubMed, EMBASE, Scopus, Web of Science and Cochrane Library were queried for retrospective cohort studies of isolated cGSWH reporting mortality prognostic factors. MOOSE guidelines were followed. Study quality was assessed using the Newcastle-Ottawa scale. Primary outcome was mortality. Pooled estimates of odds ratios and 95% confidence intervals were derived using random-effects models. 17 observational studies (1774 patients) were identified and included. Factors associated with mortality were: age >40 years (Odds Ratio 3.44; 95% Confidence Interval [1.71 to 6.91]), suicide attempt (5.78; [3.07 to 10.87]), GCS 3-8 compared with 9-15 (38.02; [21.98 to 65.77]), GCS 3-5 versus 6-8 (15.38; [6.72 to 35.23], bilateral fixed and dilated pupils versus normal (67.12; [16.67 to 270.22]), and versus unilateral fixed and dilated pupil (25.35; [5.82 to 110.41]), dural penetration (29.07; [4.30 to 196.53]), bihemispheric (4.23; [2.32 to 7.68]), and multilobar injuries (6.53; [1.99 to 21.42]). Selection for operative management, according to expert neurosurgical opinion, was protective (0.06; [0.01 to 0.22]). This is the first meta-analysis on cGSWH mortality prognostic factors. Increasing age, suicide attempt, lower GCS, bilateral mydriasis, dural penetration, bihemispheric and multilobar injury are associated with increased mortality. This study can serve as a guide to clinicians and will provide directions for future research to develop evidence-based management algorithms.
- Pupillary Responses to Robotic and Human Emotions: The Uncanny Valley and Media Equation Confirmed. [Journal Article]
- FPFront Psychol 2018; 9:774
- Physiological responses during human-robots interaction are useful alternatives to subjective measures of uncanny feelings for nearly humanlike robots (uncanny valley) and comparable emotional respon...
Physiological responses during human-robots interaction are useful alternatives to subjective measures of uncanny feelings for nearly humanlike robots (uncanny valley) and comparable emotional responses between humans and robots (media equation). However, no studies have employed the easily accessible measure of pupillometry to confirm the uncanny valley and media equation hypotheses, evidence in favor of the existence of these hypotheses in interaction with emotional robots is scarce, and previous studies have not controlled for low level image statistics across robot appearances. We therefore recorded pupil size of 40 participants that viewed and rated pictures of robotic and human faces that expressed a variety of basic emotions. The robotic faces varied along the dimension of human likeness from cartoonish to humanlike. We strictly controlled for confounding factors by removing backgrounds, hair, and color, and by equalizing low level image statistics. After the presentation phase, participants indicated to what extent the robots appeared uncanny and humanlike, and whether they could imagine social interaction with the robots in real life situations. The results show that robots rated as nearly humanlike scored higher on uncanniness, scored lower on imagined social interaction, evoked weaker pupil dilations, and their emotional expressions were more difficult to recognize. Pupils dilated most strongly to negative expressions and the pattern of pupil responses across emotions was highly similar between robot and human stimuli. These results highlight the usefulness of pupillometry in emotion studies and robot design by confirming the uncanny valley and media equation hypotheses.
- Quantifying the real-world cost saving from using surgical adjuncts to prevent complications during cataract surgery. [Journal Article]
- EEye (Lond) 2018 Jun 06
- CONCLUSIONS: Through simple scenario modelling, we have demonstrated the cost benefits provided by the use of precautionary surgical adjuncts during cataract surgery. VL costs significantly more in terms of complication management and follow-up. This supports the cataract surgeon's maxim-"if you think of it, use it".
- Iris anomalies and the incidence of ACTA2 mutation. [Journal Article]
- BJBr J Ophthalmol 2018 Jun 06
- CONCLUSIONS: In this series, ACTA2 mutation or copy number variation was not detected in children presenting for iris flocculi, whereas congenital mydriasis was associated with R179 mutation in both cases that tested positive for ACTA2 mutation. The case of congenital mydriasis without typical cardiac features of the R179 ACTA2 phenotype or intracranial vasculopathy was negative for ACTA2 mutation. While all children presenting with these iris anomalies should be offered a genetic evaluation, incidence data should inform genetic counselling, particularly in the absence of a family history of aneurysm or sudden death, or systemic signs of smooth muscle dysfunction.
- Bilateral acute angle-closure glaucoma induced by duloxetine. [Case Reports]
- ISIdeggyogy Sz 2017 Sep 30; 70(9-10):358-360
- Introduction - To present a rare case of bilateral acute angle-closure glaucoma secondary to duloxetine administered for the treatment of depression. Case presentation - A 46 year old woman developed...
Introduction - To present a rare case of bilateral acute angle-closure glaucoma secondary to duloxetine administered for the treatment of depression. Case presentation - A 46 year old woman developed bilateral closed angle glaucoma after 15 days of duloxetine usage. Intraocular pressures (IOP) were 52 and 55 mm Hg in right and left eyes respectively, with shallow anterior chamber and angle closure on gonioscopy. Discontinuing duloxetine treatment, initiation of antiglaucomatous treatment and bilateral Nd:YAG Laser iridotomy obtained normalized IOP and anterior chamber depth. Conclusion - Duloxetine, used in the treatment of depression can be responsible for acute angle-closure glaucoma by leading to mydriasis and ciliary effusion.
- Bilateral rhegmatogenous retinal detachment due to unusual retinal degeneration in Down syndrome: A case report. [Case Reports]
- MMedicine (Baltimore) 2018; 97(22):e10896
- CONCLUSIONS: In this case, the retinal degeneration was morphologically different from retinal lattice degeneration, thus suggesting that it might be involved in the onset of DS-related bilateral RD.
- Ocular involvement in neurolymphomatosis. [Journal Article]
- AJAm J Ophthalmol Case Rep 2018; 10:148-151
- CONCLUSIONS: Our patient is only the second histological demonstration of ciliary nerve involvement by NL, and the first, to our knowledge, of primary NL spreading secondarily from the ciliary nerves into the choroid. Our patient demonstrates that NL, though rare, should be included in the differential diagnosis of ocular cranial nerve palsies and ophthalmoplegia.
- Acute Glaucoma Attack Following Microvascular Decompression Surgery for Trigeminal Neuralgia. [Journal Article]
- NMNeurol Med Chir (Tokyo) 2018 May 17
- Microvascular decompression (MVD) is widely accepted as an effective surgical method to treat trigeminal neuralgia (TN), but the risks of morbidity and mortality must be considered. We experienced a ...
Microvascular decompression (MVD) is widely accepted as an effective surgical method to treat trigeminal neuralgia (TN), but the risks of morbidity and mortality must be considered. We experienced a case of acute angle-closure glaucoma attack following MVD for TN in an elderly patient, considered to be caused by lateral positioning during and after the surgery. A 79-year-old female underwent MVD for right TN in the left lateral decubitus position, and TN disappeared after the surgery. Postoperatively, the patient tended to maintain the left lateral decubitus position to prevent wound contact with the pillow, even after ambulation. Two days after the surgery, she complained of persistent left ocular pain with visual disturbance. The left pupil was dilated with only light perception, and the intraocular pressure (IOP) was 44 mmHg. Acute angle-closure glaucoma attack was diagnosed. After drip infusion of mannitol, emergent laser iridotomy was performed. The corrected visual acuity recovered with normalization of IOP (14 mmHg). The subsequent clinical course was uneventful and she was discharged from our hospital. The left lateral positioning during and after the surgery was considered to have contributed to increase IOP of the eye on the dependent side, which resulted in acute angle-closure glaucoma attack. The potential pathology is difficult to assess preoperatively, but patient management should always consider the increased possibility of this condition with age.
- [Hypertensive crisis and anticholinergic toxidrome secondary to accidental consumption of datura stramonium in two children]. [Journal Article]
- ACAnn Cardiol Angeiol (Paris) 2018 May 11
- CONCLUSIONS: Hypertension crisis and other anticholinergic clinical signs of Datura stramonium intoxication achieve favorable outcomes in children.
New Search Next
- Dynamic Assessment of Light-Induced Vaulting Changes of Implantable Collamer Lens With Central Port by Swept-Source OCT: Pilot Study. [Journal Article]
- TVTransl Vis Sci Technol 2018; 7(3):4
- CONCLUSIONS: Vault is continuously affected during movements of the pupil induced by external luminance.