- Monkeypox: a review of the 2022 outbreak. [Journal Article]Br Med Bull. 2023 Feb 06 [Online ahead of print]BM
- CONCLUSIONS: The higher numbers of HIV-positive patients in the current outbreak has allowed better description of the disease in patients co-infected with HIV and monkeypox. The absence of more severe symptoms in HIV-positive patients in the current outbreak could possibly be due to the fact that most of these patients had well-controlled HIV, although further characterization of this cohort of patients would be useful.Current treatment and vaccination options have been extrapolated from studies of other Orthopox viruses. There remains a need for more data on the safety and efficacy of these options in the context of monkeypox infections.
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- Molecular epidemiology of Japanese encephalitis in pigs and risk factors associated with causing Japanese encephalitis in pigs of Lakhimpur, the first case reported in the district of North East India. [Journal Article]J Vector Borne Dis. 2022 Oct-Dec; 59(4):356-362.JV
- CONCLUSIONS: Molecular epidemiology of JE in pigs, and humans; positive at Lakhimpur recommend the need for uninterrupted surveillance of this virus in pigs specially those areas where pig population is more and all risk factors are present.
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- Outbreak of cholera in a remote village in western India. [Journal Article]Indian J Med Res. 2022 Sep; 156(3):442-448.IJ
- CONCLUSIONS: A cholera outbreak caused by a non-haemolytic polymixin B sensitive AET strain, occurred from July 8 to 13, 2018, in a remote settlement in western India. The molecular characterization of the outbreak strains highlighted an assortment of genetic determinants, stressing the need to monitor the genetic attributes of V. cholerae O1 in outbreaks for better understanding and mapping of clinical and epidemiological changes.
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- Characteristics and Containment of 74 Imported COVID-19 Outbreaks: Experiences, Lessons, and Implications - China, 2020-2021. [Journal Article]China CDC Wkly. 2022 Dec 16; 4(50):1131-1135.CC
- After the initial coronavirus disease 2019 (COVID-19) outbreak in Wuhan, China, the outbreaks during the dynamic-zero policy period in the mainland of China have not been systematically documented.
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- COVID-19-related hospital admission in spouses of partners in at-risk occupations. [Journal Article]Scand J Work Environ Health. 2023 Feb 07 [Online ahead of print]SJ
- CONCLUSIONS: SARS-CoV-2 transmission at the workplace may pose an increased risk of severe COVID-19 among spouses in low-risk jobs living with partners in high-risk jobs, which emphasizes the need for preventive measures at the workplace in future outbreaks of epidemic contagious disease. When available, effective vaccines seem essential.
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- Coping with COVID in corrections: a qualitative study among the recently incarcerated on infection control and the acceptability of wastewater-based surveillance. [Journal Article]Health Justice. 2023 Feb 07; 11(1):5.HJ
- CONCLUSIONS: Participants supported routine WBS to monitor for SARS-CoV-2. Integrating WBS into existing surveillance strategies at correctional facilities may minimize the impact of future COVID-19 outbreaks while conserving already constrained resources. To enhance the perception and reality that correctional systems are maximizing mitigation, future measures might include focusing on closer adherence to CDC recommendations and clarity about disease pathogenesis with residents.
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- Emergence of deadly viral hemorrhagic fever disease outbreaks in West Africa. [Editorial]Virulence. 2023 Feb 07 [Online ahead of print]V
- Recent viral hemorrhagic fever (VHF) disease outbreaks caused by Ebola virus (EBOV) and Marburg virus (MARV) in West Africa are unique and alarming. The intents of this editorial are to highlight what is known about these viruses and the disease outbreaks that they cause in the African continent and elsewhere and to raise awareness of a related virus called Lassa virus (LASV) that causes endemic …
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- Correlation of important prognostic factors and CT scores in invasive and non-invasive ventilation of COVID-19 patients. [Journal Article]Ulus Travma Acil Cerrahi Derg. 2023 Feb; 29(2):163-168.UT
- CONCLUSIONS: Patients who started treatment with NIMV had relatively low poor prognostic factors, their mortality was lower. However, the total CT score at diagnosis was expected to be higher in those who were performed IMV, no significant difference was found in our study. We concluded that the severity classification of the patients cannot be made according to CT scores. CT results should be evaluated as a whole according to the patient's clinic, predisposing factors, and response to treatment.
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- Learning strategies of dental students in Buenos Aires, Argentina prior to and during the COVID-19 pandemic. [Journal Article]Acta Odontol Latinoam. 2022 Dec 31; 35(3):214-222.AO
- CONCLUSIONS: The study identified trends towards an increase in the score and consequently greater use of techniques included in the domains related to metacognition, especially among women. There is potential neutralization of the impact created by the methodological shift between the two periods (face-to-face and e-learning) probably as a result of the implicit adaptability, latent in students, regarding digital methodology, which enables them to adapt to learning in challenging situations.
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- Development of Animal Models for Emerging Infectious Diseases by Breaking the Barrier of Species Susceptibility to Human Pathogens. [Journal Article]Emerg Microbes Infect. 2023 Feb 07 [Online ahead of print]EM
- Outbreaks of emerging infectious diseases pose a serious threat to public health security, human health and economic development. After an outbreak, an animal model for an emerging infectious disease is urgently needed for studying the etiology, host immune mechanisms and pathology of the disease, evaluating the efficiency of vaccines or drugs against infection, and minimizing the time available …
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- Phylogenomic diversity of Vibrio species and other Gammaproteobacteria isolated from Pacific oysters (Crassostrea gigas) during a summer mortality outbreak. [Journal Article]Microb Genom. 2022 Dec; 8(12)MG
- The Pacific oyster (PO), Crassostrea gigas, is an important commercial marine species but periodically experiences large stock losses due to disease events known as summer mortality. Summer mortality has been linked to environmental perturbations and numerous viral and bacterial agents, indicating this disease is multifactorial in nature. In 2013 and 2014, several summer mortality events occurred…
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- Split k-mer analysis compared to cgMLST and SNP-based core genome analysis for detecting transmission of vancomycin-resistant enterococci: results from routine outbreak analyses across different hospitals and hospitals networks in Berlin, Germany. [Journal Article]Microb Genom. 2023 Jan; 9(1)MG
- The increase of Vancomycin-resistant Enterococcus faecium (VREfm) in recent years has been partially attributed to the rise of specific clonal lineages, which have been identified throughout Germany. To date, there is no gold standard for the interpretation of genomic data for outbreak analyses. New genomic approaches such as split k-mer analysis (SKA) could support cluster attribution for routin…
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- Perception of blood donation among employees of healthcare organizations during COVID-19 pandemic: A national multicenter cross-sectional study. [Journal Article]Transfusion. 2023 Feb; 63 Suppl 1:S10-S19.T
- CONCLUSIONS: Recruitment of more blood donors among health care employees is a feasible solution to improve the blood supply during a crisis. This should be based on efforts throughout the year including regular awareness campaigns and effective communication.
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- The DataHarmonizer: a tool for faster data harmonization, validation, aggregation and analysis of pathogen genomics contextual information. [Journal Article]Microb Genom. 2023 Jan; 9(1)MG
- Pathogen genomics is a critical tool for public health surveillance, infection control, outbreak investigations as well as research. In order to make use of pathogen genomics data, they must be interpreted using contextual data (metadata). Contextual data include sample metadata, laboratory methods, patient demographics, clinical outcomes and epidemiological information. However, the variability …
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- The genomic characterization of Salmonella Paratyphi A from an outbreak of enteric fever in Vadodara, India. [Journal Article]Microb Genom. 2023 Jan; 9(1)MG
- Salmonella enterica Typhi (S. Typhi) and Paratyphi A (S. Paratyphi A) are the causative agents of enteric fever, a systemic human disease with a burden of 300 000 cases per year in India. The majority of enteric fever cases are associated with S. Typhi, resulting in a paucity of data regarding S. Paratyphi A, specifically with respect to genomic surveillance and antimicrobial resistance (AMR). He…
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- Multiplex MinION sequencing suggests enteric adenovirus F41 genetic diversity comparable to pre-COVID-19 era. [Journal Article]Microb Genom. 2023 Jan; 9(1)MG
- Human adenovirus F41 causes acute gastroenteritis in children, and has recently been associated with an apparent increase in paediatric hepatitis of unknown aetiology in the UK, with further cases reported in multiple countries. Relatively little is known about the genetic diversity of adenovirus F41 in UK children; and it is unclear what, if any, impact the COVID-19 pandemic has had on viral div…
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- A step forward for Shiga toxin-producing Escherichia coli identification and characterization in raw milk using long-read metagenomics. [Journal Article]Microb Genom. 2022 Nov; 8(11)MG
- Shiga toxin-producing Escherichia coli (STEC) are a cause of severe human illness and are frequently associated with haemolytic uraemic syndrome (HUS) in children. It remains difficult to identify virulence factors for STEC that absolutely predict the potential to cause human disease. In addition to the Shiga-toxin (stx genes), many additional factors have been reported, such as intimin (eae gene…
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- A survey on the public's discrimination rate of typical rumors during the coronavirus disease 2019 epidemic. [Journal Article]Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2022 Dec 28; 47(12):1704-1710.ZN
- CONCLUSIONS: A few publics are still unable to identify typical rumors during the COVID-19 epidemic. There are associations among genders, age, and the education levels with the discrimination of some rumors. The government authorities should strengthen the true information regarding COVID-19, and therefore enhance the public's ability to identify rumors.
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- Yersinia Type III-Secreted Effectors Subvert Caspase-4-dependent Inflammasome Activation in Human Cells. [Preprint]bioRxiv. 2023 Jan 25B
- Yersinia are gram-negative zoonotic bacteria that use a type three secretion system (T3SS) to inject Yersinia outer proteins (Yops) into the host cytosol in order to subvert essential components of innate immune signaling. However, Yersinia virulence can elicit activation of immune complexes known as inflammasomes, which lead to inflammatory cell death and cytokine release aimed at containing inf…
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- Socioecological Challenges of Polio Supplementary Immunization Activities (SIAs) in the Asia-Pacific Region: A Systematic Review. [Review]J Environ Public Health. 2023; 2023:4801424.JE
- CONCLUSIONS: An effective SIAs program provides the opportunity to increase the national capacity of the polio immunization program, reducing inequities in service delivery and offering additional public health benefits in controlling polio outbreaks in both endemic and nonendemic countries. Strengthening routine immunization (RI) programmes is also important for the sustainability of SIA's programs. Despite the challenges and hurdles, many Asian countries exhibited great political willingness to boost polio immunization coverage through SIA efforts.
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- Hospitalization Rates and In-Hospital Mortality Before and During the COVID-19 Pandemic. [Journal Article]Dtsch Arztebl Int. 2022 Nov 25; 119(47):816-817.DA
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- Impact of COVID-19 Pandemic on Tuberculosis Preventive Services and Their Post-Pandemic Recovery Strategies: A Rapid Review of Literature. [Journal Article]J Korean Med Sci. 2023 Feb 06; 38(5):e43.JK
- CONCLUSIONS: Our findings and lessons learnt from the pandemic can aid in the development of future national TB control program.
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- A molecular epidemiological study on Escherichia coli in young chicks with colibacillosis identified two possible outbreaks across farms. [Journal Article]Vet Res. 2023 Feb 06; 54(1):10.VR
- Avian pathogenic Escherichia coli (APEC) is the cause of colibacillosis outbreaks in young poultry chicks, resulting in acute to peracute death. The high morbidity and mortality caused by colibacillosis results in poor animal welfare, reduced sustainability and economical loss worldwide. To advance the understanding of the molecular epidemiology, genomic relatedness and virulence traits of APEC, …
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- Growth in chikungunya virus-related research in ASEAN and South Asian countries from 1967 to 2022 following disease emergence: a bibliometric and graphical analysis. [Journal Article]Global Health. 2023 Feb 06; 19(1):9.GH
- CONCLUSIONS: Our study is the first to present the growth of chikungunya virus-related research in ASEAN and South Asian countries from 1967 to 2022. In this study, the evaluation of the comprehensive profile of research on chikungunya can serve as a guide for future studies. In addition, a bibliometric analysis may serve as a resource for healthcare policymakers.
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- The COMFORT trial: a randomised control trial comparing group-based COMpassion-FOcussed therapy and breathing pattern ReTraining with treatment as usual on the psychological functioning of patients diagnosed with cancer recurrence during COVID. [Journal Article]Trials. 2023 Feb 06; 24(1):89.T
- CONCLUSIONS: To our knowledge, this protocol describes the first RCT which directly examines the effect of a group-based psychological intervention on Irish patients experiencing cancer recurrence in the context of COVID-19. The outcome of this trial is likely to be twofold: It will determine if the psychological intervention achieves its primary objective of distress amelioration 3 months post-intervention and to establish the feasibility of delivering this intervention in a virtual format.
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- Conradi-Hünerman-Happle Syndrome and Obsessive-Compulsive Disorder: a clinical case report. [Journal Article]BMC Psychiatry. 2023 Feb 06; 23(1):87.BP
- CONCLUSIONS: The authors aim to describe a clinical case in which the patient presents with Conradi-Hünerman-Happle Syndrome and Obsessive-Compulsive Disorder. Clinical descriptions of CHHS and OCD are not available in the literature. Through this case description the authors aim to present a rare case as well as discuss an eventual association between etiology and/or pathophysiology of the two disorders.
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- The COVID-19 e-lective: using innovation to manage disrupted medical student clinical placements. [Journal Article]BMC Med Educ. 2023 Feb 06; 23(1):92.BM
- The COVID-19 pandemic changed the way we work, spend, live, and learn. The impact was felt in the health sector where hospitals cancelled elective surgery, put on hold outpatient services, and implemented new social distancing procedures and telehealth systems, to enable hospitals to increase bed capacity. For medical students, these factors meant significant disruption to their clinical placemen…
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- Action status and willingness to change health-promoting behaviors during the COVID-19 pandemic among elementary school children: a study based on Prochaska's stages of behavior change theory (TTM). [Journal Article]BMC Public Health. 2023 Feb 06; 23(1):248.BP
- CONCLUSIONS: The health of students is under serious threat due to the poor state of health-promoting behaviors and the weak desire to change behavior. By planning in educating the students, significant changes can be made in changing their behavior and improving their health.
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- Trajectory of suicidal ideation among medical students during the COVID-19 pandemic: the role of childhood trauma. [Journal Article]BMC Psychiatry. 2023 Feb 06; 23(1):90.BP
- CONCLUSIONS: The trajectory of SI among medical students can be divided into a low risk, slowly rising group and a high risk, continuous group; the more EN, PN, EA and PA experienced during childhood, the more likely medical students are to develop a high risk, continuous state of SI.
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- Disparities in COVID-19 testing and outcomes among Asian American and Pacific Islanders: an observational study in a large health care system. [Journal Article]BMC Public Health. 2023 Feb 06; 23(1):251.BP
- CONCLUSIONS: Variation of COVID-19 testing and hospitalization by Asian subgroups was striking in our study. A focus on the Asian Americans and NH/PIs population with disaggregation of subgroups is crucial to understand nuances of health access, utilization, and outcomes among subgroups to create health equity for these underrepresented populations.
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