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(EKG: ST depression or T wave inversion)
4,580 results
  • Zumba-induced Takotsubo cardiomyopathy: a case report. [Journal Article]
  • JMJ Med Case Rep 2018 Jun 10; 12(1):160
  • Chams S, El Sayegh S, … Kulairi Z
  • CONCLUSIONS: Our patient did not have one clear trigger for her overt Takotsubo cardiomyopathy other than the Zumba activity. Zumba is considered an activity with excessive sympathetic stimulation leading to catecholamine-induced microvascular spasm or through to direct myocardial toxicity, which is postulated to be behind the pathophysiology of Takotsubo cardiomyopathy. Another interesting finding in our patient was her use of spironolactone, as treatment for hirsutism, which is an aldosterone antagonist. Aldosterone actually potentiates the effects of catecholamine and thus activates the sympathetic system. Spironolactone can thus be considered as cardioprotective against the effects of catecholamine on the heart and that is why it is considered to be beneficial and subsequently improves mortality in chronic heart failure as described in several studies.
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