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(Ebola Virus Disease & Marburg Virus Disease)
483 results
  • Viral Hemorrhagic Fevers Other than Ebola and Lassa. [Review]
    Infect Dis Clin North Am 2019; 33(4):977-1002Iannetta M, Di Caro A, … Ippolito G
  • Viral hemorrhagic fevers represent a group of diseases caused by enveloped RNA viruses. The epidemiology is broadly variable, ranging from geographically localized to more diffuse infections. Viral hemorrhagic fevers are classified as category A bioweapon agents by the Centers for Disease Control and Prevention. Viral hemorrhagic fevers are severe febrile illnesses with hemorrhagic phenomena. Lab…
  • Chikungunya and O'nyong-nyong Viruses in Uganda: Implications for Diagnostics. [Journal Article]
    Open Forum Infect Dis 2019; 6(3):ofz001Clements TL, Rossi CA, … Schoepp RJ
  • CONCLUSIONS: As the use of highly specific and sensitive polymerase chain reaction-based assays becomes the diagnostic standard without the corresponding use of the less sensitive but more broadly reactive immunological-based assays, emerging and re-emerging outbreaks will be initially missed, illustrating the need for an orthogonal system for the detection and identification of viruses causing disease.
  • Serological evidence of exposure to ebolaviruses in domestic pigs from Guinea. [Journal Article]
    Transbound Emerg Dis 2019Fischer K, Camara A, … Diederich S
  • The genus Ebolavirus comprises several virus species with zoonotic potential and varying pathogenicity for humans. Ebolaviruses are considered to circulate in wildlife with occasional spillover events into the human population which then often leads to severe disease outbreaks. Several studies indicate a significant role of bats as reservoir hosts in the ebolavirus ecology. However, pigs from the…
  • Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV. [Journal Article]
    Nat Med 2019; 25(10):1589-1600Ehrhardt SA, Zehner M, … Klein F
  • Recombinant vesicular stomatitis virus-Zaire Ebola virus (rVSV-ZEBOV) is the most advanced Ebola virus vaccine candidate and is currently being used to combat the outbreak of Ebola virus disease (EVD) in the Democratic Republic of the Congo (DRC). Here we examine the humoral immune response in a subset of human volunteers enrolled in a phase 1 rVSV-ZEBOV vaccination trial by performing comprehens…
  • Cholesterol-conjugated stapled peptides inhibit Ebola and Marburg viruses in vitro and in vivo. [Journal Article]
    Antiviral Res 2019; 171:104592Pessi A, Bixler SL, … Bavari S
  • Filoviridae currently includes five official and one proposed genera. Genus Ebolavirus includes five established and one proposed ebolavirus species for Bombali virus (BOMV), Bundibugyo virus (BDBV), Ebola virus (EBOV), Reston virus (RESTV), Sudan virus (SUDV) and Taï Forest virus (TAFV), and genus Marburgvirus includes a single species for Marburg virus (MARV) and Ravn virus (RAVV). Ebola virus …
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