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(Edwards syndrome)
2,244 results
  • HO-1 overexpression and underexpression: Clinical implications. [Review]
    Arch Biochem Biophys 2019; :108073Drummond GS, Baum J, … Abraham NG
  • In this review we examine the effects of both over- and under-production of heme oxygenase-1 (HO-1) and HO activity on a broad spectrum of biological systems and on vascular disease. In a few instances e.g., neonatal jaundice, overproduction of HO-1 and increased HO activity results in elevated levels of bilirubin requiring clinical intervention with inhibitors of HO activity. In contrast HO-1 le…
  • Acute myocardial infarction in the setting of left bundle branch block: Chapman's sign. [Journal Article]
    Am J Emerg Med 2019; :158378Idris A, Hatahet M, Edris B
  • Acute myocardial infarction (AMI) diagnosis in patients with pre-existing left bundle branch block (LBBB) can be difficult. Undiagnosed or delayed diagnosis of AMI in these patients can put them at risk of having shock, mechanical complications, and death. We present a case of 77-year-old Caucasian male with a known LBBB and coronary artery bypass surgery for coronary artery disease who presented…
  • Arterial spin labeling perfusion changes of the frontal lobes in children with posterior fossa syndrome. [Journal Article]
    J Neurosurg Pediatr 2019; :1-7Yecies D, Shpanskaya K, … Yeom KW
  • CONCLUSIONS: ASL perfusion imaging identifies decreased frontal lobe blood flow as a strong physiological correlate of PFS that is consistent with the symptomatology of PFS. This is the first study to demonstrate that decreases in frontal lobe perfusion are present in the immediate postoperative period and resolve with the resolution of symptoms, suggesting a physiological explanation for the transient symptoms of PFS.
  • Fetal Echocardiographic Parameters and Surgical Outcomes in Congenital Left-Sided Cardiac Lesions. [Journal Article]
    Pediatr Cardiol 2019; 40(6):1304-1313Edwards LA, Arunamata A, … Punn R
  • This study aimed to evaluate fetal echocardiographic parameters associated with neonatal intervention and single-ventricle palliation (SVP) in fetuses with suspected left-sided cardiac lesions. Initial fetal echocardiograms (1/2002-1/2017) were interpreted by the contemporary fetal cardiologist as coarctation of the aorta (COA), left heart hypoplasia (LHH), hypoplastic left heart syndrome (HLHS),…
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