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Unbound Medicine.
(Eisenmenger syndrome)
1,408 results
  • Role of kallistatin in pediatric patients with pulmonary arterial hypertension. [Journal Article]
    Turk J Pediatr. 2020; 62(3):405-410.Pamukçu Ö, Ay D, … Narin N
  • CONCLUSIONS: Kallistatin may have a protective effect in pulmonary arterial hypertension by repairing vascular damage, inhibition of angiogenesis, strong vasodilator effect, inhibiting VEGF, and anti-inflammatory mechanism of action. To our knowledge, our study is the first one that shows the role of kallistatin in pulmonary hypertension. Kallistatin may represent a promising novel therapeutic approach for pulmonary hypertension in the near future.
  • Caudal vena cava aneurysm in a cat with Eisenmenger Syndrome. [Journal Article]
    J Vet Med Sci. 2020 May 15 [Online ahead of print]Yoo J, Ko J, … Kim J
  • A seven-month-old cat was referred for evaluation of exercise intolerance and open-mouth breathing. Based on ultrasonographic examination, caudal vena cava (CVC) aneurysm associated with right congestive heart failure resulting from congenital heart disease was diagnosed. Conservative treatment for alleviating pulmonary hypertension mildly improved the clinical signs and decreased the heart size …
  • "Treat and repair" strategy for shunt lesions: a critical review. [Review]
    Pulm Circ. 2020 Apr-Jun; 10(2):2045894020917885.Arvind B, Relan J, Kothari SS
  • The issue of operability in patients with shunt lesions and raised pulmonary vascular resistance is contentious. Several reports suggest that patients traditionally considered inoperable may be operated after treatment with targeted drug therapy for pulmonary arterial hypertension. We reviewed all the published literature of "treat and repair" approach to gain more insights into the utility of th…
  • Atrial Septal Defect with Eisenmenger Syndrome: A Rare Presentation. [Case Reports]
    Case Rep Cardiol. 2020; 2020:8681761.Forlemu AN, Ajmal M, Saririan M
  • Atrial septal defects (ASDs) are common congenital heart defects (CHD). The clinical course in patients without closure of the ASD is associated with significant morbidity and mortality in advanced age. A small percentage of patients may develop pulmonary arterial hypertension (PAH) due to left to right shunting that impacts morbidity and mortality. Advances in prenatal screening and fetal echoca…
  • Recommendations for exercise in adolescents and adults with congenital heart disease. [Review]
    Prog Cardiovasc Dis. 2020 Mar 19 [Online ahead of print]Tran D, Maiorana A, … Cordina R
  • The population of adults living with congenital heart disease (CHD) has grown rapidly in recent decades due to major advances in surgical and medical care. Although the benefits of physical activity (PA) and exercise are well recognised in the management of chronic diseases, the therapeutic role of exercise for the CHD population has been under-studied and under-recognised. In fact, people living…
  • Determinants of Sudden Cardiac Death in Adult Patients With Eisenmenger Syndrome. [Journal Article]
    J Am Heart Assoc. 2020 Mar 17; 9(6):e014554.Chiriac A, Riley DC, … McLeod CJ
  • Background Patients with Eisenmenger syndrome are known to have a high incidence of sudden cardiac death (SCD), yet the underlying causes are not well understood. We sought to define the predictors of SCD in this population. Methods and Results A retrospective analysis of all patients with Eisenmenger syndrome from 2 large tertiary referral centers was performed. ECGs, prolonged ambulatory record…
  • A Doppler ghost in the pulmonary artery. [Journal Article]
    Echocardiography. 2020 Mar; 37(3):472-473.Cagli K, Ozbulbul NI, … Golbasi Z
  • Long-standing left-to-right shunting across a patent ductus arteriosus (PDA) can result in Eisenmenger syndrome. In this report, we present echocardiographic findings of a 27-year-old female patient with pulmonary hypertension. In diagnostic work-up especially Doppler findings of the pulmonary artery suggested the presence of a reversed PDA as a cause of pulmonary hypertension. The diagnosis was …
  • Pediatric heart-lung transplantation: A contemporary analysis of outcomes. [Journal Article]
    Pediatr Transplant. 2020 May; 24(3):e13682.Riggs KW, Chapman JL, … Morales DLS
  • CONCLUSIONS: Nearly 600 pediatric patients have been listed for HLT in UNOS, although numbers are decreasing in the current era. HLT for a patient on ECMO appears to be an ineffective strategy; however, in well-selected cohorts, HLT can provide considerable post-transplant survival.
  • Emergency caesarean section of a patient with eisenmenger's syndrome: A tight-rope walk. [Case Reports]
    Ann Card Anaesth. 2020 Jan-Mar; 23(1):95-97.Gangakhedkar GR, Chhabria RD, … Palani Y
  • Successful management of a pregnant patient with complex congenital heart disease is a challenge for anesthesiologists, requiring thorough knowledge of the impact of pregnancy on the cardiac lesion. Hearing and speech impaired patients pose a barrier to effective communication between the patient and the doctors, thus increasing the anxiety and risk of complications. Here, we present a case of a …
  • Eisenmenger Syndrome: A Multisystem Disorder-Do Not Destabilize the Balanced but Fragile Physiology. [Review]
    Can J Cardiol. 2019 Dec; 35(12):1664-1674.Chaix MA, Gatzoulis MA, … Oechslin EN
  • Eisenmenger syndrome is the most severe and extreme phenotype of pulmonary arterial hypertension associated with congenital heart disease. A large nonrestrictive systemic left-to-right shunt triggers the development of pulmonary vascular disease, progressive pulmonary arterial hypertension, and increasing pulmonary vascular resistance at the systemic level, which ultimately results in shunt rever…
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