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756 results
  • Solitary Extramedullary Plasmacytoma Presenting as Asymptomatic Palatal Erythroplakia: Report of a Case. [Case Reports]
    Int J Environ Res Public Health. 2021 Apr 04; 18(7)Lalla F, Vinciguerra A, … Abati S
  • Solitary plasmacytoma (SP) is a rare malignant tumor of plasma cells with no systemic spread; however, when it disseminates and affects multiple skeletal sites, it is called multiple myeloma (MM). The etiology of solitary plasmacytoma is unknown, with two possible subtypes: solitary extramedullary plasmacytoma (EMP) and solitary bone plasmacytoma (SBP). We present a case of EMP arising as asympto…
  • From Simple Mouth Cavities to Complex Oral Mucosal Disorders-Curcuminoids as a Promising Therapeutic Approach. [Review]
    ACS Pharmacol Transl Sci. 2021 Apr 09; 4(2):647-665.Girisa S, Kumar A, … Kunnumakkara AB
  • Oral diseases are among the most common encountered health issues worldwide, which are usually associated with anomalies of the oral cavity, jaws, and salivary glands. Despite the availability of numerous treatment modalities for oral disorders, a limited clinical response has been observed because of the inefficacy of the drugs and countless adverse side effects. Therefore, the development of sa…
  • Successful GaAlAs low-level laser therapy of self-inflicted thermal burns of the palate. [Case Reports]
    SAGE Open Med Case Rep. 2021; 9:2050313X21997205.Goldemberg DC, de Melo Pino LC, … Antunes HS
  • Thermal burns of the oral cavity usually arise from ingestion of hot foods or beverages. A 38-year-old female patient presented with two painful ulcerative erythematous patches of the palate. The patient was consulted on the same day lesions appeared. Medical history was unremarkable. Clinically significant self-inflicted injuries may result in wide ulcers in the mouth and usually do not take les…
  • Oral lichen planus - case report. [Journal Article]
    Rom J Morphol Embryol. 2020 Apr-Jun; 61(2):563-567.Vlad CS, Vlad DC, … Baderca F
  • This paper presents the case of a 58-year-old heavy smoker female who came to our clinic with acute pain, as well as mastication and feeding difficulties. The macroscopic examination revealed oral erosive lesions and ulcerations. The polymorphic aspect of the lesions required the differential diagnosis of oral erythroplakia or carcinoma, which were excluded by biopsy. At the same time, we assesse…
  • Evaluation of quality of life in patients surgically treated for potentially malignant oral lesions. [Journal Article]
    Indian J Cancer. 2020 Dec 10 [Online ahead of print]Kapur N, Singla N, … John ER
  • CONCLUSIONS: OPMDs affected the physical, functional, and psychological well-being of study patients, caused discomfort, and affected their daily activities. However, the social well-being of patients was unaltered and a large number of patients were reportedly satisfied with their treatments. The timely diagnosis and management can improve the quality of life and prevent its progression to malignancy.
  • Oral leukoplakia and erythroplakia in young patients: a systematic review. [Review]
    Oral Surg Oral Med Oral Pathol Oral Radiol. 2021 Jan; 131(1):73-84.Roza ALOC, Kowalski LP, … Latin American Cooperative Oncology Group–Brazilian Group of Head and Neck Cancer
  • CONCLUSIONS: The frequency of oral leukoplakia is low in young patients. Observational studies are necessary for understanding oral leukoplakia and other oral potentially malignant disorders in younger patients.
  • Recognition of oral potentially malignant disorders and transformation to oral cancer. [Review]
    JAAPA. 2020 Nov; 33(11):14-18.Vail M, Robinson S, Condon H
  • Oral potentially malignant disorders refer to oral mucosal disorders with increased risk for malignant transformation, primarily to oral squamous cell carcinoma (SCC). Leukoplakia and erythroplakia are the most common of these disorders, but others have been identified. Transformation rates to oral cancer vary based on multiple factors. Healthcare providers should be aware of risk factors and cli…
  • Oral Potentially Malignant Disorders and Oral Cavity Cancer. [Review]
    Dermatol Clin. 2020 Oct; 38(4):507-521.Ojeda D, Huber MA, Kerr AR
  • The Surveillance, Epidemiology, and End Results program from the National Cancer Institute reports that the aggregate number of oral cavity and pharyngeal cancer cases has been increasing over the past decade and, despite an overall decline in oral cavity cancers, this increase is largely related to a dramatic increase in cancers involving oropharyngeal subsites. Early detection of oral cavity ca…
  • Oral potentially malignant disorders: A scoping review of prognostic biomarkers. [Review]
    Crit Rev Oncol Hematol. 2020 Sep; 153:102986.Mello FW, Melo G, … Rivero ERC
  • This scoping review aimed to map evidence regarding biomarkers for malignant transformation of oral potentially malignant disorders (OPMD). Seventy-three longitudinal studies investigating prognostic biomarkers for OPMD malignant transformation were included, encompassing 5612 disorders and 108 biomarkers, of which 72 were investigated by immunohistochemistry. Most biomarkers were assessed in one…
  • Efficacy of topical photodynamic therapy in the treatment of Erythroplasia of Queyrat. [Journal Article]
    Dermatol Reports. 2020 Jun 25; 12(1):8566.Iafrate M, Mancini M, … Piaserico S
  • Erythroplasia of Queyrat (EQ) is an intraepidermal carcinoma in situ presenting clinically as a sharply demarcated, slightly raised erythematosus plaque on the glans penis or the inner side of the foreskin. Various treatment modalities for EQ have been proposed, including electrocautery and curettage, topical 5-floururacil cream, imiquimod cream, isotretinoin, cryotherapy, laser therapy, radiothe…
  • [Modern perspectives of oral squamous cell carcinoma]. [Journal Article]
    Arkh Patol. 2020; 82(3):55-60.Ivina AA
  • The article is devoted to the modern perspectives of the etiology, pathogenesis, diagnosis and prognostic factors in theoral squamous cell carcinoma. In the new edition of the WHO Classification of Head and Neck Tumors of 2017, the concept of potentially malignant diseases is introduced, which include erythroplakia, leukoplakia, oral submucous fibrosis, dyskeratosiscongenita, smokeless tobacco ke…
  • [Research progress of oral erythroplakia]. [Journal Article]
    Zhonghua Kou Qiang Yi Xue Za Zhi. 2020 Jun 09; 55(6):421-424.Duan SM, Liu TN, Zeng X
  • Oral erythroplakia is an rare oral disorder with relatively high potential of becoming malignant. It has a lower prevalence but a higher malignant transformation rate than oral leukoplakia. The etiology and pathogenesis of the disease is so far not clear, but several studies have pointed to tobacco chewing, tobacco smoking, and betel quid chewing with or without tobacco and alcohol usage as etiol…
  • [Potentially malignant disorders of the oral mucosa]. [Journal Article]
    Rev Prat. 2019 Oct; 69(8):856-860.Ben Slama L
  • Potentially malignant disorders of the oral mucosa. The term "precancerous" is now abandoned in favor to « potentially malignant disorder » which provide a better view of the evolution a far from systematic. Of these disorders, leukoplakia is the most common while erythroplakia is rare. Their diagnoses are still defined by exclusion of other known white or red lesions. Despite progress in molecul…
  • Diabetes mellitus and oral cancer/oral potentially malignant disorders: A systematic review and meta-analysis. [Review]
    Oral Dis. 2021 Apr; 27(3):404-421.Ramos-Garcia P, Roca-Rodriguez MDM, … Gonzalez-Moles MA
  • The objective was to evaluate current evidence on the prevalence and risk of oral cancer and potentially malignant oral disorders among patients with diabetes mellitus. We searched PubMed, Embase, Web of Science, and Scopus for observational studies published before November 2019. We evaluated the study quality using GRADE, QUIPS, and a specific method for systematic reviews addressing prevalence…
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