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(Esophageal motility disorders)
32,757 results
  • Endoscopic Myotomy for Foregut Motility Disorders. [Journal Article]
  • GGastroenterology 2018 Feb 15
  • Khashab MA, Benias PC, Swanstrom LL
  • Peroral endoscopic myotomy (POEM) is an advanced endoscopic procedure classically performed for the treatment of achalasia. The procedure is based on principles of submucosal endoscopy and is compris...
  • Esophageal motor disorders are frequent during pre and post lung transplantation. Can they influence lung rejection? [Journal Article]
  • RERev Esp Enferm Dig 2018 Feb 09
  • Ciriza de Los Ríos C, Canga Rodríguez-Valcárcel F, … Castellano Tortajada G
  • CONCLUSIONS: significant changes in esophageal motility were observed pre-LTx and particularly post-LTx; hypercontractile esophagus was a frequent EMD found post-LTx. EMD were more frequent in the group of patients that experienced organ rejection compared to the non-rejection group. EMD leading to an impaired esophageal clearance should be considered as an additional factor that contributes to LTx failure.
  • Mechanism of Action of STW 5 in Functional Dyspepsia and IBS: The Origin of Multi-Target. [Journal Article]
  • DDDig Dis 2018 Feb 08; 35 Suppl 1:18-24
  • Allescher HD, Abdel-Aziz H
  • CONCLUSIONS: Each herbal constituent of STW 5 has distinct effects on the gastrointestinal tract, and each shows activity through different mechanisms of action: among others, the single extracts have effects on nerves, smooth muscles, epithelial, and inflammatory cells. For example, they have relaxing or tonicizing effects on gastrointestinal muscles, and they counteract inflammation through different physiological systems, contributing to the clinical efficacy through modulation of multiple therapeutic targets. Key Messages: STW 5 is a role model for the concept of multi-targeting in therapy. Especially in complex syndromes such as FD and IBS, simultaneous multi-targeting of different functional causes seems to be a more promising approach than the classical paradigm of one disease - one receptor - one effect.
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