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125,881 results
  • The Potential for Pharmacokinetic Interactions Between Cannabis Products and Conventional Medications. [Journal Article]
    J Clin Psychopharmacol 2019Qian Y, Gurley BJ, Markowitz JS
  • CONCLUSIONS: Medications that are prominent substrates for CYP2C19, CYP2C9, and CYP1A2 may be particularly at risk of altered disposition by concomitant use of cannabis or 1 or more of its constituents. Caution should also be given when coadministered drugs are metabolized by UGT or CES1, on which subject the information remains limited and further investigation is warranted. Conversely, conventional drugs with strong inhibitory or inductive effects on CYP3A4 are expected to affect CBD disposition.
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