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Did you mean: (Friedlnders Carl)?
(Friedländer Carl)
14 results
  • Oral Contraceptive Use and Breast Cancer Risk: Retrospective and Prospective Analyses From a BRCA1 and BRCA2 Mutation Carrier Cohort Study. [Journal Article]
    JNCI Cancer Spectr 2018; 2(2):pky023Schrijver LH, Olsson H, … EMBRACE, GENEPSO, BCFR, HEBON, kConFab, and IBCCS
  • CONCLUSIONS: Prospective analyses did not show that past use of OCP is associated with an increased BC risk for BRCA1 mutation carriers in young middle-aged women (40-50 years). For BRCA2 mutation carriers, a causal association is also not likely at those ages. Findings between retrospective and prospective analyses were inconsistent and could be due to survival bias or a true association for younger women who were underrepresented in the prospective cohort. Given the uncertain safety of long-term OCP use for BRCA1/2 mutation carriers, indications other than contraception should be avoided and nonhormonal contraceptive methods should be discussed.
  • StatPearls: Klebsiella Pneumonia [BOOK]
    StatPearls Publishing: Treasure Island (FL) Ashurst John V. JV Kingman Regional Medical Center Dawson Adam A Kingman Regional Medical Center BOOK
  • In 1882, Carl Friedlander first described Klebsiella pneumoniae as an encapsulated bacillus after isolating the bacterium from the lungs of those who had died from pneumonia. Originally named Friedlander's bacillus, it was not until 1886 when the bacterium garnered the name Klebsiella. Klebsiella pneumoniae is a gram-negative, encapsulated, non-motile bacterium that is found in the environment an…
  • Genetic studies of body mass index yield new insights for obesity biology. [Meta-Analysis]
    Nature 2015; 518(7538):197-206Locke AE, Kahali B, … Speliotes EK
  • Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals. This analysis identifies 97 BMI-associated loci (P < 5 × 10(-8)), 56 of which are novel. Five lo…
  • Incorporation of pazopanib in maintenance therapy of ovarian cancer. [Randomized Controlled Trial]
    J Clin Oncol 2014; 32(30):3374-82du Bois A, Floquet A, … Harter P
  • CONCLUSIONS: Pazopanib maintenance therapy provided a median improvement of 5.6 months (HR, 0.77) in progression-free survival in patients with advanced ovarian cancer who have not progressed after first-line chemotherapy. Overall survival data to this point did not suggest any benefit. Additional analysis should help to identify subgroups of patients in whom improved efficacy may balance toxicity (NCT00866697).
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