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(Gastritis and Peptic Ulcer Disease)
8,193 results
  • An overview of nanotechnology-based treatment approaches against Helicobacter Pylori. [Journal Article]
    Expert Rev Anti Infect Ther 2019Safarov T, Kiran B, … Abamor ES
  • Introduction: Helicobacter Pylori (H.Pylori) is a pathogen that infects about 50% of the world's population and is known to be responsible for gastroduodenal diseases such as atrophic gastritis, peptic ulcer and stomach cancer. Nowadays, there is no treatment that ensures complete eradication. In addition, resistance to antibiotics used in the current treatment adversely affects the success rates…
  • Low-Value Proton Pump Inhibitor Prescriptions Among Older Adults at a Large Academic Health System. [Journal Article]
    J Am Geriatr Soc 2019Mafi JN, May FP, … Sarkisian C
  • CONCLUSIONS: One in eight older adults were prescribed a PPI, and over one-third of prescriptions were potentially low-value. Most often, appropriate short-term prescriptions became potentially low value because they lacked long-term indications. With most potentially low-value prescribing concentrated among a small subset of PCPs, interventions targeting them and/or applying EHR-based automatic stopping rules may protect older adults from harm.
  • Review: Helicobacter pylori and non-malignant upper gastrointestinal diseases. [Journal Article]
    Helicobacter 2019; 24 Suppl 1:e12637Boltin D, Niv Y, … Schulz C
  • This review covers recent publications investigating the relationship between Helicobacter pylori infection and gastroesophageal reflux disease, Barrett's esophagus, eosinophilic esophagitis, peptic ulcer disease (PUD), H pylori gastritis, and functional dyspepsia. In the area of gastroesophageal reflux disease, new data suggest that reflux may have a role in the transmission of H pylori infectio…
  • Loss of a Cardiolipin Synthase in Helicobacter pylori G27 Blocks Flagellum Assembly. [Journal Article]
    J Bacteriol 2019; 201(21)Chu JK, Zhu S, … Hoover TR
  • Helicobacter pylori uses a cluster of polar, sheathed flagella for motility, which it requires for colonization of the gastric epithelium in humans. As part of a study to identify factors that contribute to localization of the flagella to the cell pole, we disrupted a gene encoding a cardiolipin synthase (clsC) in H. pylori strains G27 and B128. Flagellum biosynthesis was abolished in the H. pylo…
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