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177,176 results
  • Multireceptor fingerprints in progressive supranuclear palsy. [Journal Article]
  • ARAlzheimers Res Ther 2017 Apr 17; 9(1):28
  • Chiu WZ, Donker Kaat L, … Palomero-Gallagher N
  • CONCLUSIONS: We demonstrate, for the first time to our knowledge, that kainate and A1 receptors are altered in PSP and that clinically identifiable PSP subgroups differ at the neurochemical level. Numerous receptors were altered in the midcingulate cortex, further suggesting that it may prove to be a key region in PSP. Finally, we add to the evidence that nondopaminergic systems play a role in the pathophysiology of PSP, thus highlighting potential novel treatment strategies.
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