- HIV and Malaria Infections and Associated Risk Factors Among Febrile Illness Patients in Northwest Ethiopia. [Journal Article]
- TPTurkiye Parazitol Derg 2018 Aug 15
- CONCLUSIONS: Malaria and HIV are still common challenges independently occurring in the study area. The coexistence of the two diseases cannot be underestimated. Hence, health professionals should strengthen the provider initiative counseling and testing (PICT) program as a means of HIV/AIDS prevention and control strategy. Furthermore, approaching the febrile illness patients for both malaria and HIV diagnoses may help in having a joint HIV and malaria prevention and control strategy.
- StatPearls [BOOK]
- BOOKStatPearls Publishing: Treasure Island (FL)
- Chancroid is an exceedingly rare sexually transmitted disease, both in the United States and globally. Understanding its true prevalence is made difficult by the lack of a readily available diagnosti...
Chancroid is an exceedingly rare sexually transmitted disease, both in the United States and globally. Understanding its true prevalence is made difficult by the lack of a readily available diagnostic testing and by its similar presentation to other more common causes of genital ulcer diseases.
- The epidemiology of herpes simplex virus type 1 in Asia: systematic review, meta-analyses, and meta-regressions. [Journal Article]
- CIClin Infect Dis 2018 Jul 18
- CONCLUSIONS: HSV-1 epidemiology appears to be in transition in Asia. HSV-1 is probably playing an influential role as a sexually transmitted infection explaining one-fifth of genital herpes cases. There is a need for expanded seroprevalence monitoring and GUD and genital herpes etiological surveillance.
- Paediatric Behçet's disease in Iran: report of 204 cases. [Journal Article]
- CEClin Exp Rheumatol 2018 Jun 19
- CONCLUSIONS: The clinical spectrum of PED-BD in Iran in this study was similar to that of other reports; however, genital ulcers, skin lesions (notably erythema nodosum), and gastrointestinal involvement were noticed to occur less frequently, while ocular lesions were more frequent and more severe compared to other reports.
- Foscarnet-induced genital lesions: An overview with a case report. [Journal Article]
- DRDermatol Reports 2018 Apr 23; 10(1):7749
- Foscarnet is an important antiviral medication used mainly in the treatment of complicated Herpes-simplex virus and cytomegalovirus (CMV) infections. Reported first in the 1990's, genital ulcers are ...
Foscarnet is an important antiviral medication used mainly in the treatment of complicated Herpes-simplex virus and cytomegalovirus (CMV) infections. Reported first in the 1990's, genital ulcers are a potential side effect in about 10% of cases. We report the case of a 29 year old man with acute myelogenous leukemia who was on ganciclovir for CMV prophylaxis. Three weeks after being switched to foscarnet because of neutropenia, he developed two, painful symmetric ulcers on the inferior aspect of glans penis. Viral and bacterial cultures were negative. Two weeks after stopping the infusion of foscarnet, the ulcers subsided without any additional treatment. It is important that physicians be aware of this potentially disfiguring side effect of foscarnet so that methods of prevention can be implemented early in the treatment of these patients.
- Vulvar Hemangioma: Case Report. [Journal Article]
- RBRev Bras Ginecol Obstet 2018; 40(6):369-371
- Hemangioma is a benign neoplasm that may affect the vulva, and it can cause functional or emotional disability. This article reports the case of a 52-year-old female patient with a history of a genit...
Hemangioma is a benign neoplasm that may affect the vulva, and it can cause functional or emotional disability. This article reports the case of a 52-year-old female patient with a history of a genital ulcer for the past 3 years and who had undergone various treatments with creams and ointments. The patient was biopsied and diagnosed with vulvar hemangioma and was subsequently submitted to surgical excision of the lesion. We emphasize the importance of following the steps of the differential diagnosis and proceeding with a surgical approach only if necessary.
- Behçet disease associated with gastrointestinal amyloidosis manifested as hematochezia: A case report. [Case Reports]
- MMedicine (Baltimore) 2018; 97(26):e11153
- CONCLUSIONS: Our case shows that patients with BD may have GI manifestations due not only to entero-BD but also due to GI amyloidosis.
- Bio-behavioral survey of syphilis in homeless men in Central Brazil: a cross-sectional study. [Journal Article]
- CSCad Saude Publica 2018 Jun 25; 34(6):e00033317
- The objective of this study was to investigate the prevalence and factors associated with syphilis in homeless men in Central Brazil. It is a cross-sectional study conducted with 481 individuals atte...
The objective of this study was to investigate the prevalence and factors associated with syphilis in homeless men in Central Brazil. It is a cross-sectional study conducted with 481 individuals attending four therapeutic communities between October and December 2015. A structured interview was conducted to collect sociodemographic data and risk factors for syphilis. Rapid/point-of-care and VDRL tests were performed to determine exposure to syphilis and the presence of active syphilis, respectively. Poisson regression analysis was used to verify the risk factors associated with the outcomes investigated. Of the study participants, 10.2% were reactive to the rapid test, and 5.4% had active syphilis. At the multiple regression analysis, schooling (adjusted prevalence ratio - APR: 0.89; p = 0.005), history of genital ulcer (APR: 2.59; p = 0.002), STI history (APR: 1.97; p = 0.042), and sexual intercourse under drug effects (APR: 1.60; p = 0.022) were independent factors associated with lifetime syphilis. Also, history of genital ulcer (APR: 2.19; p = 0.019), STI history (APR: 1.74; p = 0.033) and number of sexual partners in the last year (APR: 1.02; p = 0.044) were associated with active syphilis. The prevalence of syphilis among homeless men was rather high, confirming the vulnerability of this group to this infection. These results emphasize the need for educational intervention, improvement of risk reduction programs, availability of diagnostic tests, especially the rapid test, and treatment.
- HIV infection in patients with sexually transmitted infections in Zimbabwe - Results from the Zimbabwe STI etiology study. [Journal Article]
- PlosPLoS One 2018; 13(6):e0198683
- CONCLUSIONS: The high prevalence of HIV infection in STI clinic patients in Zimbabwe underscores the importance of providing HIV testing and referral for indicated prevention and treatment services for this population. The discrepancy between positive self-reported and negative study HIV test results highlights the need for operator training, strict attention to laboratory quality assurance, and clear communication with patients about their HIV infection status.
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- Lipschütz ulcer and group A streptococcal tonsillitis. [Journal Article]
- BCBMJ Case Rep 2018 Jun 06; 2018
- Lipschütz ulcers (LU) are non-sexually related genital ulcers, rarely reported. We describe a healthy 11-year-old girl, who presented with fever and a painful vulvar ulcer associated with erythematou...
Lipschütz ulcers (LU) are non-sexually related genital ulcers, rarely reported. We describe a healthy 11-year-old girl, who presented with fever and a painful vulvar ulcer associated with erythematous tonsillitis. Throat swab test for Group A Streptococcus (GAS) was positive. She was treated with amoxicillin. Further investigation was negative, including Herpes Simplex virus DNA from ulcer swab and serology for Epstein-Barr virus, cytomegalovirus and Mycoplasma pneumoniae Antistreptolysin O titre was high. The ulcer healed in 2 weeks, with no recurrence in a 1 year follow-up period. The association of LU with GAS tonsillitis is very rare.