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4,726 results
  • The metabolic and endocrine characteristics in spinal and bulbar muscular atrophy. [Journal Article]
  • JNJ Neurol 2018 Feb 20
  • Rosenbohm A, Hirsch S, … Ludolph AC
  • CONCLUSIONS: Metabolic alterations in glucose homeostasis (diabetes) and fat metabolism (combined hyperlipidemia), and sex hormone abnormalities (androgen insensitivity) could be observed among SBMA patients without association with the neuromuscular phenotype. Dehydroepiandrosterone sulfate was the only biomarker that correlated strongly with both weakness duration and the CAG repeat length after adjusting for age and BMI, indicating its potential as a biomarker for both disease severity and duration and, therefore, its possible use as a reliable outcome measure in future therapeutic studies.
  • Changing practices: The addition of a novel surgical approach to gynecomastia. [Journal Article]
  • AJAm J Surg 2018 Jan 29
  • Wyrick DL, Roberts M, … Mancino AT
  • CONCLUSIONS: The "double donut" technique is particularly useful for males with grades II or III gynecomastia. It provides good wound results, with acceptable patient satisfaction and cosmetic outcomes. Although initially developed for patients with higher grade gynecomastia, the improved visibility and increased patient satisfaction allowed this to become the preferred technique at our institution.
  • [Gynaecomastia]. [Journal Article]
  • ULUgeskr Laeger 2018 Jan 22; 180(4)
  • Paulsen JF, Berg JO, … Jørgensen N
  • Gynaecomastia (GM) is a benign proliferation of the glandular tissue of the male breast and results from an imbalance between androgen and oestrogen. Pubertal GM is found in 50% and often resolves sp...
  • Klinefelter syndrome: more than hypogonadism. [Review]
  • MMetabolism 2018 Jan 27
  • Kanakis GA, Nieschlag E
  • Klinefelter syndrome (KS) is the most frequent chromosome disorder in males (1:650 newborn males), defined by 47,XXY karyotype. The classical phenotype is that of a tall male with relatively long leg...
  • Evidence-Based Practice in Liposuction. [Journal Article]
  • APAnn Plast Surg 2018 Jan 24
  • Collins PS, Moyer KE
  • CONCLUSIONS: The benefits of UAL and LAL over SAL include the following: (1) UAL over SAL in the treatment of gynecomastia, (2) LAL and UAL over SAL with decreased hemoglobin/hematocrit in high-volume lipoaspirates, and (3) LAL over SAL with skin tightening in select areas specifically the submental area. Otherwise, the literature demonstrates equivocal results among the described techniques with no clear benefit to set one apart from the other. There appears to be no demonstrable added benefit to the addition of either UAL or LAL that would urge a change in practice patterns outside the exceptions listed.
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